■---■■•■•• b v^. \3 ^£>^ ^ ^ DR. JOB T. DICKINS. S Pleasant street, - Aewburyport. SPECIFIC MEDICATION AND SPECIFIC MEDICINES. BY JOHN M. SCUDDER, M. D. PROFESSOR OP THE PRINCIPLES AND PRACTICE OF MEDICINE IN THE ECLECTIC MEDICAL INSTITUTE J AUTHOR OF " THE PRINCIPLES OF MEDICINE," " THE ECLECTIC PRACTICE OF MEDICINE," " THE ECLECTIC MATERIA MEDICA AND THERAPEUTICS," "A PRACTICAL TREATISE ON THE DISEASES OF -WOMEN," ETC. CINCINNATI: WILSTACH, BALDWIN & CO., PEINTEKS. 1870. Entered according to Act of Congress, in the year 1870, by JOHN M. SCUDDEE, In the Office of the Librarian of Congress. PREFACE. For some hundred years or more, there has been a pretty uniform agreement in the statement, so frequently repeated — " there are no specifics in medicine." To have a good reputa- tion for professional acquirements and standing, this was a fun- damental article of belief. Whatever might be the certainty in Anatomy, Physiology, Chemistry, and the arts of the Ob- stetrician and Surgeon, it was essential to believe that the practice of medicine was a great uncertainty. That it was a great uncertainty, as commonly followed, we are well assured. The records of disease, the mortality tables, and the resultant lesions from the mal-administration of medicines, abundantly testify to this. This stands confessed in the writings of the most prominent men in the medical profession to-day, who unite in deprecating the use of the older treatment of disease, and the greater safety of the expectant plan — which is really diet and rest. Must we give up medicine entirely? Are there no agencies opposed to processes of disease, that we can employ with cer- tainty ? These are the questions of the day, and in answering them, we will decide either for no medicine, or for specific medication. To determine which of these shall be chosen, the reader will have to refer to his own experience of the action of medi- vi PREFACE. cines, and be guided by it. All will admit the uncertainty of medicine, as now used, but no one will be willing to confess that lie really knows nothing in therapeutics. I think it will be safe to assert that every practitioner will have the knowl- edge of some antagonism of medicine to disease, that is clear, definite and uniform. If he has but one such, it is positive proof there are others, and the evidence that direct or specific i medication is a possibility. Specific medication requires specific diagnosis. We do not propose to teach that single remedies are opposed to diseases according to our present nosology. These consist of an asso- ciation of functional and structural lesions, varying in degree and combination at different times, very rarely the same in any two cases. To prescribe remedies rationally, we are required to analyze the disease and separate it into its component ele- ments, and for these we select the appropriate remedy. The writer has had a sufficiently extended experience in the treatment of disease, to say that he knows absolutely that remedies have this direct antagonistic action to disease, and in many instances he is able to define it so that the reader can readily determine its truth. Still the field of investigation is a broad one, it has been but little cultivated, and there are few careful observers, so that much of the work remains for future investigation. The tendency of medicine in all schools, however, is in the one direction. The giving up of the old uncertainty is the first step, then follows the careful study of individual reme- dies, and their use to accomplish certain well defined objects. One need not be a prophet to forecast the future in this respect. The medicine of the future will very certainly be direct, or as we have chosen to term it, " Specific Medication." PREFACE. Vli The object of the author has been to make the subject as plain as possible, and not to obscure it with useless verbiage. The first intention was to tell only what he knew — then this small volume would have been but a pamphlet. But on fur- ther consideration it was deemed best, to point out the lines of investigation with the larger number of our indigenous medi- cines, that they might be thoroughly tested. No apology is offered for its shortcomings. It has been compiled in considerable part, from monthly articles in the Eclectic Medical Journal, and is presented to the profession as a guide in part, but especially as an incentive to the re- study of the Materia Medica. SPECIFIC MEDICATION AND SPECIFIC MEDICINES. THE THEOKY OF SPECIFIC MEDICATION. I take it for granted that the reader will concede that all agents employed as medicines act either upon function or structure, and that this action to be curative must be opposed to the processes of disease. This proposition seems so plain that it re- quires no presentation of facts in proof, yet it is well to give it careful consideration, and arrange such facts as may have come under the reader's ob- servation in its support. If the action of a remedy is to oppose a process of disease, evidently its selection will depend — first, upon a correct knowledge of the disease, and second, upon a correct knowledge of this opposition of remedies to it. It is a law of the universe, "that like causes always produce like effects," or to reverse it, " that like effects always flow from like causes." There- fore, if we cau determine the opposition of a remedy V 10 SPECIFIC MEDICATION. to a process of disease in any given case, we have determined it in all like cases. And, to make use of this knowledge subsequently it is only necessary that we be able to determine the exact condition of disease, when we very certainly expect to obtain the same curative (opposing) action from the remedy. In describing this action to another, it is neces- sary— first, that we so observe and group the signs and symptoms of disease, that he may get the exact idea of the pathological condition to ba opposed. The skill required is in diagnosis, and necessitates a very thorough re-study of pathology, ignoring to a great extent, our present nosology. To facilitate this study, the author has published a work — " The Principles of Medicine " — which embodies his views, and will serve as a basis for specific or direct medi- cation. Much that might be deemed necessary in this monograph, will there be found in its proper connection, and we have not deemed it desirable to separate it and reproduce it here. Many persons are in error in regard to our use of the term specific. They think of a specific medicine, as one that will cure all cases of a certain disease, according to our present nosology, as pneumonitis, dysentery, diarrhoea, albuminuria, phthisis, etc. ; and a person looking at the subject in this light, and guided by his experience in the use of remedies, would at once say there are no specifics. We use the term specific with relation to definite pathological conditions, and propose to say, that SPECIFIC MEDICATION. 11 certain well determined deviations from the healthy state, will always be corrected by certain specific medicines. A disease, according to our present nosology, may be formed of one, or of a half-dozen or more distinct pathological changes, bearing a determinate relation to one another. We do not propose to reach all of these by one remedy, except in those cases in which one lesion is primary, and the others result from it. But on the contrary, we propose a remedy for each pathological feature, using the remedy for that first which is first in the chain of morbid action, and that second which stands second, and so on. As an example, we analyze a case of fever, and find it to consist of a lesion of the circulation, a lesion of innervation, a lesion of secretion, a lesion of the blood, and a lesion of nutrition ; each of these is regarded as a distinct element of the dis- ease, but in the order named, — the one depending upon the other to a certain extent. A remedy that will rectify the lesion of circulation, will sometimes be sufficient to arrest the entire chain of morbid phenomena — as we notice in the simple fevers. Or a remedy that will correct the lesiou of the blood — this being primary and the cause of the various morbid processes, — will be a specific for all, as when quinine arrests an intermittent or remittent fever. But in the severer types of disease, we find it necessary to use a remedy or remedies for each path- ological feature. Thus, we employ one to correct the lesion of circulation, one to correct the lesion 12 SPECIFIC MEDICATION. of innervation, special remedies to increase secre- tion, to correct the lesion of the blood, etc. Instead of one remedy to arrest the disease, according to the ordinary use of the term specific, we employ a number of different agents, which are none the less specific, for they meet distinct features of the dis- eased action. To employ remedies in this way, it is requisite that we analyze the disease according to what we know of pathology, determining definitely the ele- ments that go to form it, and their relation to one another. And secondly, that we know the direct influence of remedies upon the human body, both in health and disease ; that we use them singly or in simple combinations ; that we do one thing at a time : that first which is first, that second which holds the second place, and so on. If one expects to obtain the advantages of specific medication, he must not associate it with indirect medication. The direct sedatives, with free podo- phyllin catharsis — veratrum in pneumonia, with nauseants, blisters, etc., are incompatible. Success comes from one or the other alone. If I use direct medication I use it alone, and if I use indirect medi- cation I use it alone. If we propose to treat a case of croup with Aconite, we do not use nauseants ; if we propose to cure a case of cholera infantum with Ipecac and Nux Vomica, we do not want as- tringents. — But we go further into the analysis of diseased SPECIFIC MEDICATION. 13 action as expressed by symptoms, than many sup- pose. The success of direct medication comes from the defmiteness of diagnosis — determining the exact condition of a function or part. To illustrate, it is not sufficient in selecting a sedative to know that the pulse is frequent, using alike Veratrum, Aconite, Digitalis, G-elseminum, or Lobelia. Frequency is but one element of the lesion : and we have to determine in addition the strength or weakness of the circulation, the degree of obstruction of the capillary circulation, and the condition of the nervous system that controls this function. Thus, where there is strength with fre- quency we employ Yeratrum ; feebleness with fre- quency, Aconite ; excitation of the nervous system with strength and frequency, Gelseminum ; atony of the nervous system and tendency to stasis of blood, Aconite and Belladonna ; feeble impulse from trie heart, without capillary obstruction, Digitalis, etc. It is not sufficient to know that the tongue is coated, indicating an impairment or arrest of diges- tion. We make this secretion give us the history of blood lesions, as well as of gastric and intestinal derangements. We learn that pallid mucous mem- branes with white coat demand alkalies ; that deep red mucous membranes and brown coat call for acids ; that a dirty-white, pasty coat requires the alkaline sulphites, etc. It is not necessary to con- tinue this illustration further, for the reader will see by the above that the specific medication requires spe- 14 SPECIFIC MEDICATION. cijic diagnosis, and that it will be successful just in proportion as we become skilled in this. It is true that almost any one can use Yeratrum and Aconite successfully, for the conditions are so prominent that they can not be mistaken ; or any one may successfully prescribe Aconite in sporadic dysentery from cold ; Ipecac in the diarrhoea of chil- dren ; Collinsonia or Hamamelis for hemorrhoids ; Collinsonia for ministers' sore throat; Cactus for heart disease ; Pulsatilla for nervousness ; Staphy- sagria for prostatorrhoea ; Eryngium Aquaticum for cystic or urethral irritation ; Apocynum Canabinum for dropsy, etc., etc. These remedies have an extra value attached to them, because the conditions in- dicating them are so easily determined. Yet the reader will learn with surprise that ten years since, with but one exception, not one of these agents were used for the purpose named. In 1860, 10 lbs. of the crude root of Collinsonia supplied the market for a year ; now one house gets in 10,000 lbs. for the year's supply. SPECIFIC DIAGNOSIS. We have already insisted upon the necessity of specific diagnosis if we are to expect definite cura- tive action from medicines. This is a very impor- tant element of specific or direct medication that many physicians do not seem to understand. When we speak of specific medication they get the idea of an absolute cure for disease according to our SPECIFIC DIAGNOSIS. 15 present nosology, and say there is no such thing as a specific medicine. They expect to guess at the name of a disease, and find a remedy that will fit their guess-work. To suit such, a medicine must be like a blunderbuss, scattering its shot all over the field, giving a probability that some will reach the mark. Direct medication, on the contrary, requires spe- cific diagnosis. We must know exactly what the de- parture from health is, and knowing this we may select a remedy which will correct it. As was re- marked before, the physician must have first a thor- ough knowledge of healthy life, and be able to re- cognize it, or any departure from it. Thus Anat- omy and Physiology are the true basis of direct medication, for if we do not know the healthy structure and function, it is not possible that we can know the diseased structure and function. We have a very simple rule for measuring the departure from health, and it is easily applied. It is in one of three directions — excess, defect, or perver- sion— above, below, or from. If we can measure disease in this way, the desired remedial action is at once suggested — if in excess it is to be diminished, if defective it is to be increased, if perverted it is to be brought back to the normal standard. In a majority of acute diseases, we will find these de- partures so clearly marked that the diagnosis and treatment are very easy. But as there are many elements that go to make healthy life in man, so there are many that go to 16 SPECIFIC MEDICATION. make the sum of disease. These will be found in varying combination, yet in most cases there are certain prominent lesions which may be regarded as standing first in the chain of morbid phenomena and upon which the others rest. If we can find remedies which will reach and correct these, the disease is at an end, and the natural restorative power of the body soon gives health. The most simple form of specific medication is where a single remedy is sufficient to arrest the pro- cess of disease. As when we prescribe Collinsonia for ministers' sore throat, Drosera for the cough of measles, Belladonna for congestive headache, Ma- crotys for muscular pains, Hamamelis for hemor- rhoids, Phytolacca for mammary irritation, Cactus for functional heart disease, Staphysagria for pros- tatorrhoea, etc. This use of remedies gives great satisfaction in the treatment of many diseases, and we are led to wish that the practice of medicine could be resolved into the giving of such specifics. Not quite so simple, but yet very plain is the second form of direct medication, illustrated by the following examples. A heavily loaded tongue at base, with a bad taste in the mouth and fullness in the epigastric region, demanding an emetic. A uniformly yellowish coated tongue from base to tip, relieved by Podophyllin or Leptandrin. A pallid tongue, coated white, calling for a salt of soda. A pallid large tongue, with a moist pasty coat, de- manding the alkaline sulphites, say sulphite of soda. The deep red tongue and mucous membranes with SPECIFIC DIAGNOSIS. 17 brownish coatings, demanding the use of acids, say muriatic acid. Quite as plain, but not so easily and directly reached by medicine, is the need of a good condi- tion of the intestinal canal for digestion and blood making, and associated with it the recognition of the need of certain restoratives that may be neces- sary to normal nutrition and functional activity. These are essentials in the treatment of every form of disease. In acute cases, it is required first to rid our patient of functional disease before we can fully establish digestion and nutrition, but in chronic dis- ease it will many times stand first, and must always be associated with treatment for local lesions. The complement of this is, treatment to increase the removal of old and word-out tissues, and thus relieve the solids and fluids of material that must necessarily depress functional activity. Probably we have as little positive knowledge of remedies that increase retrograde metamorphosis, as of any other class, still they are being studied, and in time we will be enabled to use them directly. Remedies that increase excretion are in common use, and form a very important part of our practice. From the earliest periods of medicine, the fact that dis- ease is destructive has been recognized. Destruc- tion of the material of our bodies, necessarily leaves the debris either in solids or fluids, and experience has shown that it can not remain in the body with safety. Hence the common use of those agents 18 SPECIFIC MEDICATION. that stimulate excretion from skin, kidneys and bowels. But there has been a failure to appreciate the true nature of these processes, and from this has flowed a very great deal of bad practice. These processes are strictly vital processes, carried on by delicate organisms under the control of the nervous system. As they are the basis of life, we may well suppose that nature has guarded them on all sides, and that they are the true centre of life. The doc- tor of the olden time has looked upon them as mechanisms to be powerfully influenced by reme- dies. He powerfully excites the stomach and intes- tinal canal as a means of derivation, and works upon the skin and kidneys as if secretion from them were a purely physical process. Thousands of lives have been and are being destroyed in this way. Any one who will take up Huxley's Physiology, and read the clear and simple description of this apparatus for digestion and waste, upon which our lives rest, can not but be satisfied that the common practice of medicine is a very great wrong. A man lives, because he has the power of renewing his life day by day. Take away this power and he will die in a brief time ; take it away in part, and you have lesseued his power to that extent ; take it away for an hour, for a day, or for a week, and his power to live is weakened to that extent. When we regard these processes as strictly vital processes, in highly developed organs, under tile control of a most delicately adjusted nervous system, SPECIFIC DIAGNOSIS. 19 we will be in a position to nse remedies to aid vital action. Studying the condition of the stomach and intestinal canal in this light, we will see how a direct stimulant, or tonic, an alkali, an acid, a rem- edy that will relieve nervous irritation, or one that will give increased innervation, will in different cases be an aid to digestion. Looking farther, we will see the necessity, in one case of histogenetic food, in another of calorifacient, in one of iron, in another of phosphorus, etc. It is just as much specific medication to be able to select the proper food for the sick as it is the proper medicine. One or two examples of this may not be out of place. The past winter I was called in consultation, in a case of continued fever in the third week. The treatment, so far as medicine was concerned, had been very judicious, but the food had been starchy, and for a week the patient had been able to take very little. He was failing fast, and stimu- lants and tonics were used without advantage. The most striking features of the disease to me were : the feebleness of the heart's action, the want of respiratory power, and the evidences of a general failure of muscular power — in all other respects the patient was in good condition. I advised enemata of beef-essence, and its internal administration in small quantities frequently repeated, and a suspen- sion of all medicine. The effect was marked in twenty -four hours, and the patient speedily recov- ered. In the early part of my practice I had occa- sion to call Dr. William Judkins in consultation, in 20 SPECIFIC MEDICATION. the case of a lady who had incipient phthisis de- veloped from menstrual irregularity. She was very feeble, and 1 had been giving ^her freely of the bit- ter tonics, stimulants and animal food. The old Quaker remarked, if thee will stop the medicine and stimulants, and give her fatty matter she will recover — and the result justified the old doctor's skill in diagnosis. I have had to take this advice twice in the past eighteen months, from other par- ties, when I should have recognized it myself ; in both it was the one thing necessary to success. With regard to excretion, we must be thoroughly impressed with the fact that it is wholly a vital pro- cess, and not a process of straining. When we come to understand that a secreting organ is con- tinually growing secreting cells, and that these withdraw from the blood the worn-out materials of our bodies, we will be in a position to use remedies with better success. Evidently it is possible to so over-stimulate or over-work an excretory organ, that this function of cell-production will be very much diminished or altogether arrested. Just in this proportion must secretion be impaired or wholly arrested. The best remedies to increase secretion are those that act mildly and stimulate vital function. Thus far direct medication is very plain sailing. All can succeed with it, yet successes will be in pro- portion to the physician's acuteness of observation, and to some extent upon his knowledge of remedies. But beyond this we have a field that requires a very thorough knowledge of vital processes, accurate ob- DIFFERENCE FROM HOMEOPATHY. 21 servation, and an extended knowledge of remedies. We study not so much the grosser manifestations of disease, but the more delicate shadings and com- binations, and our therapeutics requires that we have a most intimate knowledge of the influence of remedies upon the human body. In this field of study the physician will find a beauty and certainty in the practice of medicine that will give zest to in- vestigation, and as it is pursued he will find greater and greater success. DIFFERENCE FROM HOMCEOPATHY. The question has been asked, "In what does your theory of specific medication differ from Homoeop- athy ? " The question is a pertinent one, and I will endeavor to answer it briefly. The law, similia sim.Uibus, upon which the Ho- moeopathic practice is based, is defined in two ways. One contends that the drug, used for cure, " pro- duces the essential morbid condition " when proven in health. The other, " that it produces similar symptoms," but not the exact pathological condi- tion. The truth in this law of similia similibus, is, that certain agents, called medicines, act on particular organs, parts, and functions of the human body in a uniform manner. They act equally on the organ, part, or function, in health and disease ; and thus acting in health, they produce such change in the phenomena of life as to render the action sensible 22 SPECIFIC MEDICATION. to the person — symptoms. If an agent directly and uniformly produces an influence upon a particular part, it is more likely to be used as a remedy in dis- ease of that part than another which does not influ- ence the part at all. Remedies are, therefore, those agents which directly and uniformly influence an organ, part, or function. The question then comes up, are they remedies because " they will produce a similar state of disease," or because they are opposed to diseased action ? The Homoeopaths will not admit any explanation of their law of similia. The remedy is a remedy because it will produce the exact diseased condition, or at least the exact symptoms of such condition. I contend that a drug is a specific remedy : first, because it influences uuiformly and directly the part or function diseased ; and second, because it opposes such diseased action. I would, therefore, write the law of cure opponens opponenda, instead of similia similibus. I find a late authority in Homoeopathy agrees with me in this. Dr. v. Grauvogl, in his " Lehr- buch Der Homoeopathy," says : — " The conception of a specific remedy expresses the mutual relation existing between it and parts of the organism, which has to be ascertained empirically by physio- logical provhigs of drugs. For some part of the organism is in a relation of immunity, for other parts of attraction, for others again one of repulsion, and always vice versa. For instance, there is a spe- DIFFERENCE FROM HOMEOPATHY. 23 cific form of fever and ague which, for these very reasons, is cured by Quinine, a dose or quantity of Quinine being given which corresponds to the in- tensity of the attack." Again with reference to the dose of medicines : " All we have to do is to determine, independently of all subjective persuasions and incomprehensibili- ties, what quantity of a substance is necessary in order to produce in any morbidly affected part of the organism a chemical or physical counter-move- ment of equal intensity, and in an opposite direction to the movement originated by the -morbific cause, with a view of arresting, or at least, retarding this latter, and finally- discontinuing it altogether by re- peating the dose. * . * .# The problem is simply to determine what remedial movement quantities will antagonize as their equivalent the movements that had been excited by the morbific agent; for the measure of the force is the effect, nothing else. To solve this problem we have the natural law according to which quantity contains the measure of the movement and counter-move- ment; consequently for therapeutic purposes, the correct dose consists in a quantity of force of the indicated quality which is equal to the quantity of force of the morbific agent, and in its movements runs in a contrary direction to the quality of the latter." In ordinary practice, whether it be Old School or Eclectic, there is no principle or law of cure. Rem- edies are not given because they are opposed to or 24 SPECIFIC MEDICATION. agree with diseased action, but simply because they have been previously used with reputed good suc- cess. It is, in fact, pure empiricism. The old dog- ma of phlogosis and antiphlogistics, and the new doctrine of impaired vitality and restorative medi- cation, guides the empirical use of remedies in the one or other direction. THE ADMINISTKATION OF MEDICINES. We may lay it down as an axiom, from which it is never safe to depart, that — No medicine should be given, unless the pathological condition and the indica- tions for its use are clearly defined. It is much better to employ a placebo, than run the risk of doing harm by medication. Good nursing is an essential element in the suc- cessful practice of medicine, and always requires direction by the physician ; keeping the stomach in good condition for the reception of food and medi- cine, is of first importance, and requires attention. Following this is the selection of proper food, its preparation, and the time for its administration. These alone very well repay the careful attention and thought of the physician, even if he can not see an indication for the employment of remedies. "When we recollect that the cause of disease is always depressing, and a source of constant renewal, we will see that the removal of the cause from the patient or the patient from the cause, or the antag- onism of remedies to remove the cause, is a proper ADMINISTRATION OF MEDICINES. 25 field for our efforts. If we cau see clearly that the condition of disease is one of depression — that in proportion as a man is sick, his vitality is lessened, such means as will increase the power to live, or the resistance of the body to death, will be sug- gested. As we have stated before, we make an analysis of the disease and divide it into its component parts, before making a prescription of medicine. There are certain basic functions or conditions upon which all otters rest, and which are essential to life. These demand our first consideration. Thus the circulation of the blood, the temperature, the condition of the nervous system, waste, excretion, the condition of the blood, blood-making and nutrition, are examined separately. Determining the lesion of these, we prescribe such remedy as antagonizes it, and brings the function toward the healthy standard. Some one of them will stand first in the series of patho- logical changes, and will serve as a basis for others, and this will receive first attention. Thus we pre- scribe at the other lesions, in the order in which they seem to be arranged. As a rule, it is best to do one thing at a time. We prescribe first for that lesion which is first in the chain of morbid action. Then maintaining the in- fiuence obtained by a continuation of the remedy, we do that second which is second, and that third which is third, and so on. In the cure of disease time is an important ele- ment, and it is never best to be in a hurry. Here, 3 26 SPECIFIC MEDICATION. the old proverb " haste makes waste," is a very true one. As a rule, the severer the disease, the slower its development ; the slower the departure from' health the greater the impairment of function and structure, and necessarily the slower its restora- tion. The manifestations of life in man are from a highly developed organism, the perfection of which is a work of time. Every manifestation of life ne- cessitates a continued renewal of structure, requir- ing an expenditure of that force we k%ow as vital. Therefore, when the manifestations of life are ab- normal (disease), we must necessarily allow time for the development of the organism, increased because the vital force is impaired. As a rule, it is best to change the manifestations of diseased life slowly, giving sufficient time for the or- ganism to adapt itself to the change, and gain in- creased strength as it returns to the condition of health. It will never do to suppress a process of disease at the risk of suppressing the organism upon which natural function depends. As a rule, it is best to effect these changes insensibly, or without shock to an organ or to the entire body. In this, as in all other things, it is the slow but con- tinued application of an opposing force, that ac- complishes the greatest results. Many thousands of sick have been hurried to their graves by the sudden and forcible 'efforts of the physician to re- move disease. This is one of the most prominent THE FORM OF MEDICINE. 27 errors of the old practice, and will require consid- erable effort to avoid. ' As a rule, it is best to employ remedies singly, or in simple combination of remedies acting in the same way. The reasons for this rule are obvious. It prevents random or scattering prescriptions. We either know a single remedy that will accomplish the ob- ject, or we know nothing and have no right to make a prescription. There can not be anything in a combination that is not in the individual articles composing it, and in some one of them par excellence: this is the remedy to use. In direct medication we want no modifying influences ; we want the plain and constant action of a simple remedy. THE FORM OF MEDICINE. The common action of many medicines obtained in the old practice is the poisonous action. The agent is given in such large doses and is so nauseous, that the human body in self-preservation is forced to act upon and expel it. Thus, an emetic forces the stomach to an act of expulsion, and we have emesis ; a cathartic influences the intestinal canal in like manner and we have catharsis ; and so with diaphoretics and diuretics. A different class, which may be represented by mercnry, antimony, and arsenic, obtain entrance to the blood, and depressing this, they depress every manifestation of life until they are finally slowly removed. If we desire to obtain these grave influences of 28 SPECIFIC MEDICATION. medicine, the form is not particular, neither is the size of the dose — if the patient can stand it. But if we desire that slow, insensible, but direct action that I have spoken of, we want our remedies in such form that they will be kindly received and have a kindly action upon the organism. We have also to take into consideration the pre- servation of the article, uniformity of action, pleas- antness to the sick, portability, and ease of pre- scription. These hold a secondary place, yet are very important. A class of remedies may be regarded as chemicals, and these we desire in greatest purity, and only purchase such as bear the names of the best manu- facturers. Such are Quinia, Morphia, Sulphite of Soda, Phosphate of Soda, the Bromides, etc. The largest class is obtained from the vegetable world, and are products of nature's laboratory. These we wish unchanged b\^ art, as nature ha3 prepared them, simply reducing the bulk, and using a vehicle to preserve them. Very certainly the best menstruum for all vege- table remedies is alcohol and water in varying pro- portion. There is no vegetable product that does not yield its medicinal properties to these, in a very concentrated form, the alcohol being in sufficient propprtion for preservation. .Not only so, but with modern apparatus for percolation, the fluid may easily represent the strength of ounce for ounce, giving sufficient concentration to make it portable. The tincture thus prepared is miscible with water, the form: of medicine. 29 which is undoubtedly the best vehicle for the intro- duction of a remedy into the blood. In using a hypodermic injection, we employ water as a vehicle for the medicine, and not simple syrup, syrup of lemon or ginger, an extract of quassia or other nasty substance, and so in introducing remedies into the circulation we will find water decidedly the best vehicle. Remedies in pura naturalibus are not offensive, it is the covering them up, and mixing them that makes them unpleasant. Doctors' potions are pro- verbially nasty, and the public mind has been culti- vated to believe that a mixture in a bottle must be an offence to smell, taste and stomach. The thoughts of such medicines are enough to make some sick. My prescriptions are uniformly made with water as a vehicle, the tincture being added to it in such proportion that the dose will be a teaspoonful. If the tinctures are carried in the pocket case, we add them to ft glass of water in proper proportion, and renew the medicine at each visit that it may be fresh. In the treatment of diseases of children this ex- temporaneous dispensing is especially desirable. Children are naturally adverse to anything un- pleasant, and one ordinary drugging is sufficient to " put them against medicine." It is very unpleasant to be required to force medicine upon a child against its wishes, still more to throw it down, hold it for- cibly, and grasping its nose make it swallow the 30 SPECIFIC MEDICATION. mixture. No wonder parents turn from such prac- tice to Homoeopathy. It has been my practice to have the little patient see all the operations of preparing the medicine. It sees the pocket case, inspects the bottles, and is convinced that everything is clean and there is nothing objectionable. The glass of water is placed before it, and the few drops of medicine added, and to the request, " My dear, taste this and see if the medicine is not good," it offers no objection, is sat- isfied, and you have obtained the little patient's confidence, and will never lose it until you abuse it. THE DOSE OF MEDICINE. As a rule, the dose of medicine should be the smallest quantity that will produce the desired result. The proper dose, or that which gives the best result, is very much smaller than one who has been used to the large doses of indirect medicine would suppose possible. Yet it is not infinitesimal, as our Homoeo- pathic friends would have us believe. It is difficult to state what the dose should be as yet, but I be- lieve those named in connection with the remedies are the maximum. A few examples may serve to illustrate this. In the olden time we thought the dose of a strong tincture of Macrotys was from half to one teaspoon- ful, repeated every two or three hours, until " the head felt like bursting." I now find the remedy much more certain in the proportion of 5j. of the PREPARATION OF REMEDIES. 31 tincture to water giv. a teaspoonful every two hours. The common directions for using Veratrum (Nor- wood's Tincture) were to commence with a dose of three drops every three hours, increasing one drop each hour, until its full effect was produced. Now the dose is always less than one drop. Aconite was formerly given in doses of drops, now in fractions of drops. The dose will vary in different cases, and with different practitioners. If it falls below the grass or poisonous action of the drug, it will have specific influence, and the diagnosis being right, will accom- plish the object of the prescriber. I am satisfied that the size of the dose does not make such differ- ence as has been thought, and that the essential element of success is to get the right remedy. THE PREPAKATION OF KEMEDIES. The majority of physicians will prepare but few remedies themselves, yet it is just as essential that they know how they should be prepared, as if they made them all. With an intelligent understanding of the simpler processes of pharmacy, he will have a much better knowledge of the physical properties of medicines, and be enabled to judge somewhat of their purity and efficiency when purchasing. The general drug trade has been a miserable fraud upon the profession. Whether selling crude or manufactured articles, the chances were ten to one that they were adulterated, and not what they 32 SPECIFIC MEDICATION. were represented, (Morphia, Quinia, and some of the common chemicals, have been exceptions.) So far has this sophistication been carried that all certainty in medicine, even in gross drugging for indirect effect, has been lost. Solid or fluid ex- tracts are found of all degrees of strength, from the highest named in the pharmacopoeia to nothing. In many cases they are prepared from old and worthless crude material, that has partly or wholly lost its medicinal properties, yet it is sold in the same packages and at the same prices, as if good. There is but one safe plan for the physician in procuring remedies, and that is by personal experi- ment to satisfy himself that a good remedy can be readily prepared, and learn to know it when he sees it. Deal with houses that claim to prepare remedies from recent crude material, of full strength, without heat, and return every package that does not come up to the full standard of strength and excellence. It is well to adopt a simple nomenclature for fluid medicines. Let them be called tinctures, as they are prepared with alcohol, and specify the strength ounce for ounce, of crude material to fluid preparation. I insist that all vegetable remedies should be pre- pared from the recent crude material obtained at its proper season. In some cases the remedy does not materially deteriorate within the year, and may be kept in stock until the next season for gathering. But in all cases it is better if prepared at once after gathering, and in many the preparation should be PREPARATION OF REMEDIES. 33 from the fresh article before any dessication. The reasons are obvious — the medicinal properties are found in the juices of the plant, or stored in its cells, principally of the bark. In both cases drying removes the medicinal principle, to a greater or less extent. The medicinal principles of plants are to a considerable extent complex and unstable organic bodies, and time, with its constant processes of change and decay, changes, deteriorates, and finally destroys them. Strength of Fluid Remedies. — As before re- marked, a remedy is desirable in proportion as it is easily carried and dispensed, (leaving out of the question its medicinal action), hence concentration becomes an important element of pharmacy. A skilled manufacturer who has the proper appliances, has no difficulty in removing all the medicinal prop- erties from vegetable products, so that one Troy ounce of crude material will be contained in one fluid-ounce of the tincture. This may be accomplished by the simple process of percolation, in most cases. In some pharmacies this is supplemented by powerful, pressure; in other cases, the hydraulic press being employed with ad- vantage. In other establishments, the new process of percolation under atmospheric pressure, has been adopted with great advantage. Either of these methods if carefully and honestly conduced will give reliable and uniform remedies. If we can make up our minds that it is quality, rather than quantity, that we should look after, slight variations 34 SPECIFIC MEDICATION. of strength will make but little difference. I do not wish to be understood, however, as admit- ting that there can be any great variation of medicinal strength, if recent crude material is used, and the product represents ounce for ounce, and the pharmaceutical processes have been skillfully conducted. Physical Properties of Fluid Remedies. — The fluid preparations should possess the exact physical properties (intensified), as regards odor and taste, of the fresh crude material. It will have the color of the chlorophyll of the article, but should be clear and transparent, and give no sediment, or muddiness when shaken. These may seem like minor matters, yet we will find it profitable to give them attention. Skilled pharmacy gives fine look- ing remedies, and they are likely to be good. Un- skilled pharmacy gives dirty-looking preparations, and they are likely to be inferior. We may judge to a considerable extent of the goodness of chemicals in the same way. If we find our Sulphate of Quinia and Morphia presenting the clear white silky or feathered crystals, we are satis- fied that we have good remedies. But if it is dull, discolored, crystals faint, broken, or amorphous, we want none of it. So in the purchase of the Bro- mides, Iodides, Salts of Potash and Soda, Iron, etc., we expect to find the highest physical qualities, associated with purity and efficiency. If a salt is discolored, or in any wise deficient in its appear- ance, we want none of it. OFFICE PHARMACY. 85 OFFICE PHAKMACY. There are good reasons why every physician should have such knowledge of pharmacy, that he can perform or direct all the simpler operations for preparing medicines. Without this knowledge, Jiis education is deficient, in that he has not that know- ledge of his tools which is so essential to good work. He is in a condition to be imposed upon by imper- fect and worthless remedies, and must surely lose confidence in medicine, except given in large doses, for its gross effects. In country practice, a knowledge and practice of office pharmacy is an important element of success. The preparation of a remedy gives an interest in it that leads to thorough study and careful use. We learn what a good preparation is, and its advantages over the common stock in the drug trade, and we will afterward use moru care in making our pur- chases. It economizes time, saves money, and cul- tivates habits of thrift, all of which are deficient in the medical profession. It is not only an excellent school for the physi- cian himself, but is also an admirable school for the student. It is a study of the Materia Medica, that gives a practical knowledge of remedies, and im- presses the mind through the organs of sense, leav- ing lasting impressions. I do not wish to be understood as advising the preparation of all medicines ; or keeping the office 36 SPECIFIC MEDICATION. dirty ana unsightly with the refuse of roots, barks, and herbs. This is the opposite of what we desire ; skill is associated with neatness and cleanliness. I know some pharmacists that are so slovenly and dirty in person and surroundings, that I should not like to take their medicines. (The only one who ever offered an objection to office pharmacy, had these faults in excess.) A half dozen neat tin percolators of the capacity of two to ten pounds, hung in a closet or cupboard, with a large mortar, comprises the apparatus. The alcohol is kept in stock, and the crude material is procured at proper seasons and used fresh, or in some cases is ordered of the wholesale druggist when obtaining other medicines. The process of percolation is a very simple one. The crude material requires to be as finely commi- nuted and as closely packed in the percolator as possible. It is then covered with alcohol, and allowed to stand for forty-eight hours, when the tincture is drawn oft*. Filter it through paper, and you have a fine looking remedy, that will give sat- isfaction whenever used. In office pharmacy I have advised the strength to be oviij. of the crude material to the pint of alcohol, because it is more easily manipulated by one who is not expert. All the formula in this work are of this strength, for every remedy named may be prepared in the office. The physician in the country will probably pre- pare only those remedies that are indigenous, and CLASSIFICATION OF REMEDIES. 37 at the proper season the year's supply. It is not very difficult to find some one to gather the crude material, and the preparation comes at that season when there is least to do. CLASSIFICATION OF KEMEDIES. I have been in doubt in regard to the best plan of arranging the remedies in this study. Evidently the old classification will not serve our purpose, for it deals with indirect action ; and the influence of remedies in poisonous doses. We have not ad- vanced far enough to make a new classification ; at least, to make one that would facilitate our study. I have, therefore, concluded to take up the different articles in alphabetical order, and so far as possible make a brief review of our entire Materia Medica. When a remedy has no especial value, it will be named so ; and when it seems to have a specific ac- tion, not fully determined, this will be pointed out for future experiment. Self-deception is a very un- profitable pursuit, and great care will therefore be employed to insure accuracy, and no statement made unless pretty thoroughly proven. The best preparations, and the best process tor office manufacture will be given, also the form in which we deem it desirable to use them. When we have thus given the Materia Medica a review, we will be better able to make a classifica- tion. Some suggestions, however, as to the general in- 38 SPECIFIC MEDICATION. dications for treatment, and use of remedies, may not be out of place, and will serve as a further illus- tration of our idea of specific medication. In all acute, and most chronic diseases, our exam- ination of the patient and our therapeutics will take this order : 1. With reference to the condition of the stomach and intestinal canal — bringing them to as nearly a normal condition as possible, that reme- dies may be kindly received and appropriated, and that sufficient food may be taken and digested. 2. With reference to the circulation of the blood, and the temperature — obtaining a normal circulation as regards frequency and freedom, and a temperature as near 98° as possible. 3. With reference to the presence of a zymotic poison, or other cause of dis- ease— which may be neutralized, antagonized or re- moved. 4. With reference to the condition of the nervous system — giving good innervation. 5. With reference to the processes of waste and excre- tion— that the worn-out or enfeebled material may be broken down and speedily removed from the body. 6. With reference to blood-making and repair — that proper material be furnished for the building of tissue, and that the processes of nutri- tion are normally conducted. These are general outlines for the study of dis- ease,* and the action of remedies in antagonizing it, and may aid in giving direction to our study, and enable each one to make a classification of remedies for himself. A brief consideration of each one, with examples of the application of remedies, CLASSIFICATION OF REMEDIES. 39 though it will be a repetition, may be of advantage to the student. 1. The condition of the stomach is of first im- portance in the treatment of disease. It must be in such condition that it will receive remedies kindly, and permit their speedy absorption, in order that they give us the desired results. Surely, it is not difficult to see the necessity of this, if we take no further view than to obtain the curative ac- tion of remedies. If the stomach does not receive a remedy kindly, is irritated by it, we can not ex- pect ready absorption, or the complete curative action. If the stomach throws out its juices, which digest or decompose a remedy, we can not expect its curative action. If the stomach is secreting mucus in large quantity, if it is in that condition in which it is but a receptacle or retainer, then we can not expect the ready absorption of remedies, and will not get their curative action. We are accustomed to specify two conditions of the stomach, which may be tolerably easily deter- mined by constant symptoms, and which should always be corrected. These are : — Irritation of the stomach, marked by a reddened (bright) tongue, elongated and pointed, with some- times reddened and erect papillse. It is accom- panied with unpleasant sensations of constriction, and tenderness on pressure over the epigastrium. There may be nausea, retching, or vomiting ; and in the severer cases, when prolonged, an irritation 40 SPECIFIC MEDICATION. of the sympathetic, and finally of the spinal and cerebral nervous systems. Its treatment takes precedence of everything else, for until removed we can not expect the kindly or definite action of remedies. The remedies employed for its removal are : minute doses of Aconite ; small doses of Ipecac or Lobelia ; Hydrocyanic Acid, or better, a prepara- tion of the bark of the Peach tree; Rhubarb; Bismuth. These may be aided by the external use of the cold pack, hot fomentations, or rubefacient application, and sometimes an enema to remove the torpor of the lower bowel. From twelve to forty- eight hours, is usually the time required to effect it. But, the reader may ask, why if remedies are specific, name so many for the relief of so simple a pathological condition as gastric irritation ? The question is pertinent, and we will endeavor to answer it. Each of these remedies has a direct ac- tion in this condition, and each may be relied upon as a remedy. We choose the remedy, however, with reference to the association of diseased action, and in some cases one will be found best, in others another. b. The atonic stomach, with increased secretion of mucus, and sometimes with considerable accu- mulations. It is marked by the broad tongue, heavily coated at its base, bad taste in the mouth, and feeling of weight and heaviness in the epigas- trium. The symptoms are distinct, and can not be mistaken. CLASSIFICATION OF REMEDIES. 41 When the condition is pronounced, in severer forms of disease, there is no means which will reach it so directly and speedily as an emetic. It needs to he prompt and thorough in action, not producing debility or leaving the organ irritable. If not re- quiring this, we may accomplish the same object by the use of the Alkaline Sulphites, followed by Nax Vomica. We have many minor lesions that can not be classified under these, to which we will find single remedies specific. Thus in simple nausea and vom- iting, without irritation, we prescribe Kux Vomica. In typhoid disease, with tumid mucous tissues, the Baptisia. Increased mucous secretion with irrita- bility, Oxide of Zinc. Imperfect gastric secretion, Hydrastis. Increased mucous secretion with im- paired functional activity, minute doses of Podo- phyllum, etc.* 2. We recognize the fact, that just in proportion to the variation of the circulation and temperature from the normal standard is the severity and activity of disease. The more frequent the pulse, and the higher the temperature, the more active a zymotic poison, the more rapid the progress of local or general disease, and the less able the body to protect itself, or expel the cause of disease. The rule here is absolute, and there is no variation from it. In therapeutics we find — that just in proportion as the circulation and temperature can be brought to, and *See Practice of Medicine, page 27. 4 42 SPECIFIC MEDICATION. maintained at the normal standard, just in that propor- tion are the processes of disease arrested, and vital pro- cesses re-established. These facts must surely have been noticed by ob- servers, and we can only wonder that they have never been clearly stated, and practiced upon. If we take as an example a case of fever, we will find that remedies that will reduce the pulse to a normal frequency, giving freedom to the circula- tion, will reduce the temperature, and that just in proportion as this is accomplished, the febrile symp- toms disappear, and the various vital functions are re-established. If we maintain the circulation and temperature at this point, the fever must certainly cease. In acute inflammation, the rapidity of the local disease and destruction of tissue, is in the ratio of frequency of pulse and increase of temperature. Just in proportion as we get a normal circulation with reference to frequency and freedom, and diminished temperature, just in that proportion the inflammatory process is arrested. In asthenic inflammation we find another element in the pathology of the disease — a want of vital power, either in the whole or in the part. This must be antagonized by appropriate remedies. In others there is a zymotic or animal poison, which must be antagonized, destroyed, or removed. In chronic disease the law is just as absolute as in the acute. Given, any disease of function or structure, with a pulse maintained constantly above CLASSIFICATION OF REMEDIES. 43 100 beats per minute, and a temperature above 100°, and the patient must die. The disease, as a general rule, will run its course rapidly to a fatal termina- tion just in proportion to the extent of this devia- tion. Recovery from chronic disease . never takes place until the circulation and temperature approximate a normal standard. In any given case, the proba- bilities of cure are as the possibility of bringing and maintaining the circulation and temperature at the standard of health. The first evidences of amend- ment are announced by a diminution of frequency of pulse and a better circulation of blood, and by an equal temperature of the body, approximating 98°. These seem like dogmatic statements, and many will be inclined to dispute them, because op- posed or not named by the common authorities on medicine, but it only requires observation without prejudice to prove each position. We may claim then, that remedies influencing the circulation and temperature, toward the normal standard, are the most important of the Materia Medica. In very many cases the lesion of the circulation is a basic lesion, upon which others arise and are continued. When this is the case, the remedy that gives us normal circulation removes all the diseased processes which rest upon it. Thus we will find that arrest of secretion and excretion, lesions of in- nervation, of waste and nutrition, as well as the in- tensity of zymotic causes, are in proportion to the 44 SPECIFIC MEDICATION. rapidity of the circulation. Conversely, as the pulse comes down to the normal standard, and the blood circulates freely, just in that proportion we have a restoration of the secretions and excretions, better innervation, better digestion and blood-mak- ing, and a more active waste and repair. Have we remedies that influence the circulation directly, giving a free and equal circulation, with diminution of frequency ? Many of our readers will have asked this question before this, and an- swered it in the negative. Certain remedies will have been recommended to them as special sedatives, which they have used without the good results named and expected. How is this ? It is a com- mon failing with physicians to expect a desired re- sult too soon, and endeavor to force it by large doses of medicine. This has been a common cause of failure in the use of Veratrum and Aconite. Others have purchased worthless medicines, which will readily account for the failure. Taking the article of Veratrum alone, and excepting Norwood's Tinc- ture, nine-tenths that has been sold was wholly worthless as a medicine. The theory with regard to the action of the class of special sedatives was erroneous. They were re- garded as depressants, and diminished frequency of pulse was supposed to depend upon their depressing influence upon the heart. It was the common error of large doses and poisonous action. All of these remedies are active poisons in large doses, and death occurs in all by cardiac syncope. In the cases CLASSIFICATION OF REMEDIES. 45 of Veratrum, Digitalis, Lobelia and Gelseminum, slowness of pulse is a prominent symptom of the poisonous action. In the case of Aconite, extreme frequency of pulse is produced by the poisonous action. In medicinal doses (small), the influence of these remedies is that of a cardiac stimulant, and is un- doubtedly through the sympathetic system of nerves, which controls the entire circulation of the blood — not only the action of the heart, but of all the blood-vessels to the most minute capillary. I contend that this influence removes obstruction to the free circulation of the blood, as well as gives power to heart and muscular fibre of arteries. As obstruction to free circulation is removed, it requires less effort to move the blood ; as the power of mov- ing the blood is increased there is less necessity of frequency of contraction upon the part of the heart. As a rule, the time required to effect sedation will bear a distinct relation to the time required for the development of disease, and its average dura- tion. Thus in an acute fever or inflammation from cold, the influence of the sedative maybe promptly obtained, and the disease speedily arrested. In continued fever, the accession of the disease (in most cases), is slow in proportion to its duration and severity. Here there are grave lesions of function, possibly of structure, and we expect to obtain the influence of the sedative slowly.* *See Principles of Medicine, pp. 219, 264. The Eclectic P^e tice of Medicine, page 94. 46 SPECIFIC MEDICATION. Whilst each of the remedies named as arterial sedatives, Aconite, Veratrum, Digitalis, Gelsemi- num, Lobelia, exert a direct influence in this direc- tion, they are not equally valuable in all cases. The two first are pre-eminently the sedatives, their action being more definite and stronger, and adapted to a larger number of cases. The special adapta- tion of each to special forms of diseased action is named in the description of the remedy. The temperature bears such a constant relation to the frequency of pulse, and general condition of the circulation, that a remedy which will correct the one will also correct the other. Thus we find in practice that just as we bring the pulse to the normal standard by the use of an arterial sedative, in the same degree we reduce the temperature. This is the case in chronic as well as in acute dis- ease. For instance, in a case of phthisis we find a temperature of 101° associated with a pulse above 100 beats per minute ; if it is possible to bring the pulse down to 80 the temperature comes down to 98° and a fraction. If this can be maintained we find a cessation of tubercular deposit, and a repara- tive process set up in the lungs. "We have some special means to influence the temperature, outside of the remedies acting upon the circulation. A full description of them would be out of place here, but may be found iu my Prin- ciples of Medicine, p. 40. 3. The field of therapeutics embraced in our third proposition is very large, and will well repay careful CLASSIFICATION OF REMEDIES. 47 study. Whilst zymotic causes have been recog- nized in many of the severe acute diseases, but little has been done to determine their character, or the means to antidote them. Possibly the observations of Prof. Polli, with regard to the influence of the Alkaline Sulphites, was the first important step in this direction. The presence of such blood poison is readily de- tected, and we have advanced so far in our knowl- edge of remedies, that in many cases we can select the antidote with much certainty. I do not wish to -be understood as claiming that we have any remedies that will immediately unite with all of a zymotic poison in the blood, destroy it, and at once restore health. Such an influence could not reason- ably be expected. But we have remedies which, introduced into the blood, will antagonize the zy- motic poison, as it comes in contact with it, arrest- ing its septic influence, or wholly destroying it. In some cases they act rapidly, in others slowly, but in all, if properly selected, with great certainty. The principal remedies of this class are the Alka- line Sulphites, (Sulphite of Soda being in most common use) and the mineral acids. The rules for the selection of the one or the other of these are quite simple, and very definite : In any given case presenting a pallid tongue, with white, or dirty-white, pasty coating, use the Alkaline Sulphites. In any given case presenting a deep-red tongue with brownish coatings, or deep-red glossy tongue, 48 SPECIFIC MEDICATION. and dark sordes, use mineral acids. In some cases we employ Sulphurous Acid, but in the majority, Muriatic Acid. Of our indigenous Materia Medica we have but one remedy that markedly possesses these proper- ties, and it possesses it in high degree. This rem- edy is the Baptisia Tinctoria, which may be used in either of the cases named, but is especially valued in the last. The reader will bear in mind that the activity of a zymotic poison is in exact proportion to the de- parture from normal function. With a rapid pulse, high temperature, and arrest of secretion, its devel- opment is rapid and its devitalizing influence marked. Or in the rare opposite case of congestive intermittent and cholera, as the circulation is en- feebled, and the temperature lowered, its progress is rapid. Hence, in order to antagonize a zymotic process, it is necessary, so far as possible, to obtain a normal circulation and temperature. This proposition can not be too strongly insisted upon. In a given case, the circulation and temperature being favorably in- fluenced by Aconite and Veratrum, Sulphite of Soda exerts an immediate and marked controlling influence over the fever poison. Whilst if it had been given without such preparation it would have had no influence at all, or but slight influence. Some causes of disease are destroyed and removed by remedies that increase waste and excretion. Pre- parations of Potash and Soda, especially the alka- CLASSIFICATION OF REMEDIES. 49 line diuretics act in this way. There are some organic remedies that exert a direct influence upon causes of disease, modifying or destroying them, as may he instanced in the action of Phytolacca in diphtheria. This action, however, in the majority of cases, is feehle. Causes of disease acting in and from the blood, are frequently removed by stimulating the excretory organs. Some are removed principally by the skin, others by the bowels, others by the kidneys. The cause of periodic disease, whatever it may be, plays a very important part in the diseases of some localities. Antagonize this cause, and the disease ceases, or at least is very much modified. Hence in the treatment of the diseases of the West, antiperiodics become the most important remedies. Quinia is a true specific, and may be taken as the type of these remedies. It fails frequently, possibly it is administered nine times where its specific action is obtained once. But it is not the fault of the remedy, but of the doctor. If the diagnosis is cor- rectly made, and the system is prepared for its ad- ministration, it will rarely fail, even when given in a single sufficient dose. I am satisfied that the study of the direct antag- onism of remedies to causes of disease, must ad- vance the progress of rational medicine. It is pos- sible, and I deem it probable, that such research will give us remedies controlling all zymotic disease in its early stage. 4. The human body is a complex structure, united 5 50 SPECIFIC MEDICATION. in functional activity by a nervous system. As this exerts a controlling influence, we should expect that its lesions would form a very important element of the study of pathology. This has not been the case, however, and we find pathologists and therapeutists giving it but very little attention. It is a wide field for study, and its cultivation will greatly advance medical science. A few suggestions may not be out of place here : Those functions which we have been accustomed to speak of as vegetative, are associated together, and to some extent governed by the ganglionic or sym- pathetic nervous system. It comprises digestion, blood-making, the circulation of the blood, nutri- tion, and secretion and excretion — these are the es- sentially vital functions, in the performance of which man has life. If they are properly performed, he has healthy life, if there is an aberration in either of them, one or more, he has diseased life. Is it possible to have disease, without a lesion of one of these ? I think the reader will say it is not. If this be so, then this ganglionic system of nerves must play an important part in every disease.* Control and association of these vital processes being in the ganglionic system of nerves, we would naturally expect it to furnish the readiest means of reaching them aud correcting their lesions. If there are remedies then that influence the gangli- onic nerves directly, and through them the vital *See Principles of Medicine, page 306. CLASSIFICATION OF REMEDIES. 51 processes of the body, they must become oar most direct and important therapeutic means. It is in this way that a large number of specific remedies act, as I believe. The sedatives, Aconite, Veratrum, Gelseminum, Lobelia and others, as Cactus, Bella- donna, Eryngium, Phytolacca, Hamamelis, Pulsa- tilla, etc., very certainly produce their effects through it. The association of the spinal-cord with the sym- pathetic brings vital functions in relation with our conscious life, and through its superior expansion the brain, adds suffering from disease. Conversely, mal-conditions of conscious life are reflected through this association and influence vital processes. Whilst, therefore, it is very important to reach lesions of vegetative life directly through the gan- glionic system of nerves, it is no less important to control any disease producing influence that might be extended from the cerebro-spinal centres. 5. Lesions of waste and excretion are elements of every disease. In some they form a principal part, in others in less degree, but in all they require to be estimated in diagnosis and therapeutics. They range themselves under the common classification of excess, defect, and perversion, and usually it is not difficult to determine their character, and select means that exert a direct influence. Constant waste is a necessity of life, as is constant removal of this waste. If the materials of the body are not broken down and removed as they have served their purpose, the body is old, imperfect, and 52 SPECIFIC MEDICATION. has lost functional power to this extent. If the material is broken down and removed to the blood, hut not carried out by the excretions, we will have an impairment of life from its presence in the blood. I have given this subject full consideration in my Principles of Medicine, pp. 116 to 185, to which the reader is referred. Too rapid waste of tissue is sometimes an impor- tant element of disease, requiring care in diagnosis and the application of remedies. A perversion in waste and excretion is a common element of disease. In the breaking down of a protean body, it passes through many phases, and in its metamorphosis, it assumes forms that are noxious to life, if they have any degree of perma- nency, or are in any considerable quantity. Lesions in retrograde metamorphosis are therefore to be esti- mated, and remedies which influence it become im- portant. We have already noticed that many causes of disease act in and from the blood. They are zy- motic poisons, or animal matter undergoing change, and influence the blood and life in different degree, in proportion to their quantity, and especially in proportion to their activity in setting up the septic process. These may be antagonized or destroyed in many cases ; in others the natural process of re- trograde metamorphosis is stimulated, and they are transformed into urea and other innocuous bodies fitted for excretion by kidneys, skin and bowels. Means that increase the activity of these excretions CLASSIFICATION OF REMEDIES. '53 are frequently sufficient for the removal of such causes of disease. 6. The necessity of regarding the nutritive pro- cesses during the progress of disease, is now admit- ted by all advanced physicians, and insisted upon by such writers as Chambers, Anstie, Bennett and others. Experience has conclusively proven that proper food with good condition of the digestive apparatus, without medicine, give a success in the treatment of the graver acute diseases, that was never obtained by any other method of treatment. As we have already seen, the condition of the stomach and digestive apparatus is of first impor- tance in all forms of disease, and its lesions demand first attention in our therapeutics. We have shown that this was essential to the successful administra- tion of remedies, it is no less necessary that the patient may take and appropriate proper food. The administration of remedies that increase functional activity of the digestive apparatus, or aid in the digestive process, are sometimes important means. The selection of appropriate food, and the use of restoratives is supplemental to this. The object is to place the digestive organs in good con- dition to receive and prepare food for admission to the blood ; to furnish such material to the blood as may be necessary for its perfect organization, and for the renewal of tissue. 54 SPECIFIC MEDICATION. ABIES CANADENSIS. (Hemlock.) This agent has been employed in medicine for a long time — the bark in decoction as an astringent, the foliage in hot infusion as a diuretic and diapho- retic, and the oil as a stimulant local application. It undoubtedly possessess valuable properties. The following properties and uses are suggested to those who live where it may readily be obtained : 1st. A tincture of the recent mnerbarkin diluted alcohol ; use in general asthenia with pallid mucous membranes, and feeble digestion : also, in diseases of the respiratory mucous membranes. 2nd. A tincture of the foliage in dilute alcohol ; use in irritation of the urinary organs, and in dis- ease of the skin. iESCULUS GLABRA, (Buckeye.) Preparation. — Whilst the bark possesses medicinal properties in considerable degree, and maybe used, a tincture of the nuts will probably be the best preparation. Take of the recent nuts, fully ripened, four ounces ; bruise them thoroughly, and cover with alcohol 76° one pint ; let it stand for two weeks ; strain and filter. Of this tincture add from one to two drachms to four ounces of water — the dose being one teaspoon- ful. .ESCULUS GLABRA. 55 The buckeye has been used to but a limited ex- tent in medicine, yet its activity is such (as a poison), that it will probably prove very valuable when thoroughly studied. In my boyhoodr I well remember persons carrying " buckeyes " in their pockets as a sovereign cure for " piles," and at a later period as a remedy for rheumatism. Doubt- less this suggested the first use of the ^Esculus in medicine. It has been used in the treatment of hemorrhoids with*much success, and I am satisfied that in some forms of the disease it is the most certain remedy we possess. I have also given it in a few cases of diseased uterus with good results — cases in which the entire organ was enlarged, the cervix tumid, with too frequent recurrence of the menstrual flow. The marked influence of the ^Esculus on the ner- vous system would suggest a line of experiment likely to lead to the development of valuable prop- erties. It has already been employed as a stimu- lant to the nervous system in some cases of paraly- sis. We may reason in this way : a remedy that cures hemorrhoids must exert a powerful influence upon the circulation ; whilst its poisonous action, often witnessed — vertigo, diminished sight, wry neck, fixed eyes, paralysis, convulsions, etc., show its in- fluence upon the nervous system. 56 SPECIFIC , MEDICATION. ^ESCULTJS HIPPOCASTANUM. (Horse Chestnut.) Preparation. — Take of the recent nut, fully ripe, four ounces, bruise it thoroughly, and cover with alcohol 76° one pint ; let it stand fourteen days and filter. Dose, two to four drops, in water. The bark of this variety has been employed to a limited extent as a tonic, and possesses feeble anti- periodic powers. Quinine being employed to break the chill, this agent was sufficient to prevent its re- currence. The pulverized kernel has been used as a sternutatory for the relief of headache and facial neuralgia. The nuts were also thought to possess some special influence over hemorrhoids and rheu- matism. The influence upon the nervous system is similar in kind to the buckeye, though not so active. This probably will be its best field of action, standing midway between Belladonna on the one hand and Nux Vomica on the other. It exerts the same influence upon the circulation as the ^Esculus Glabra, and has been successfully employed in the treatment of hemorrhoids. It will doubtless be found to improve the circulation gen- erally, and may be employed whenever there is want of power in the heart, capillary stasis, or ten- dency to congestion. ACIDS. 57 ACIDS. There is a specific use for acids in the treatment of disease, which we wish to study carefully. In any form of disease we may have an excess of the alkaline salts of the blood. This may be the basis of diseased action, or but a complication rendering it more intense, but whether the one or the other, it needs to be recognized and have direct treat- ment. The indications of excessive alkalinity are very plain, and need not be mistaken by the youngest practitioner. The color of the mucous membranes is deep red, especially of mouth and tongue ; the coating of tongue, sordes, or any exudative mate- rial, has a dark color, usually brownish. It makes no difference what the diseased action is, in its to- tality, or what it is called, the deep red, somewhat dusky color always demands the administration of acids. There is but one exception to this, and that is a rare one, in which the excess is of Soda, but with a defect of Potash. In this case the administration of a Salt of Potash will answer a better purpose than the Acid, or may be combined with it. The Muriatic Acid is preferable in most acute cases, and' should be used so diluted, and in such quantity, as to be pleasant to the patient, and until the indication for its use is removed. Lactic Acid is sometimes preferable with children, and in some 58 SPECIFIC MEDICATION. cases of chronic disease, especially when associated with indigestion. The vegetable Acids may be used in acute disease, but are not so good as those named. ALKALIES. It is well to consider the specific use of alkalies in this relation ; as they are the opposite of acids. We may say of these, as of acids, that their defi- ciency is found as a constituent element in all forms of disease — in some cases being the basis of a mor- bid action, in others but a complication ; but, when- ever found, an important element and demanding direct treatment. The symptoms of deficiency of these salts of the blood are very plain, and, using the language of the Prophet, " He who runs may read." The tongue is pallid and broad, its coating pasty and white, or yellowish white. The mucous membranes are uni- formly pallid. As these evidences are absolute and readily determined, it is not necessary to name others not so constant. Whenever we find this deficiency of the alkaline salts we will observe, as the result : loss of power in the stomach, enfeebled digestion and slow ab- sorption, impairment of the circulation, arrest of nutrition and waste, and enfeebled innervation. These will correspond in degree to the deficiency. So marked are these results, that I have long re- garded the diagnosis, with regard to excess or defi- ciency of the alkaline salts, as of the highest im- ALKALIES. 59 portance. Indeed in some forms of disease, espe- cially of a typhoid character, it is the principal ele- ment upon which a successful treatment is based. Soda is the natural salt of the blood, and exists in the body in the largest proportion. Whenever, therefore, we have the evidence of deficiency of the alkaline salts, and uo special symptoms indicating others we will give a Salt of Soda. In many cases I order Bicarbonate of Soda in water, in such quan- tity that it will make a pleasant drink, and let the patient have it freely. If, at the same time, we wish an antiseptic influ- ence, we may give the Sulphite or Hoposulphite of Soda or the Chloride of Sodium. I am satisfied that I have seen patients die from deprivation of common salt during a protracted illness. It is a common impression that the food for the sick should not be seasoned, and whatever slop may be given, it is almost innocent of this es- sential of life. In the milk diet that I recommend in sickness, common salt is used freely, the milk being boiled and given hot. And if the patient can not take the usual quantity in his food, I have it given in his drink. This matter is so important that it can not be repeated too often, or dwelt upon too long. The most marked example of this want of com- mon salt I have ever noticed has been in surgical disease, especially in open wounds. Without a supply of salt the tongue would become broad, pallid, puffy, with a tenacious pasty coat, the effusion CO SPECIFIC MEDICATION. at tJae point of injury serous, with an unpleasant watery pus, which at last becomes a mere sanies or ichor. A few days of a free allowance of salt would change all this, and the patient would get along well. A Salt of Potash is indicated where there is fee- bleness of the muscles to greater extent than can be accounted for by the disease. Occasionally such want is expressed in a marked manner by feebleness of the heart. Ammonia will, occasionally, prove the best salt for temporary use, especially where there is great debility. But when so used, it should be followed by the free use of common salt, or some salt of soda. ACHILLEA MILLEFOLIUM. (Yarrow.) Preparation. — Prepare a tincture of the recent herb, §viij. to Alcohol 50° Oj. Dose, gtts. v. to 5ss. This agent, though feeble in its action, is much better than many in common use. It acts directly on the urinary apparatus, and the reproductive organs of the female. I have used it to allay irri- tation of the kidneys and vesical and urethral irri- tation. In these cases its influence is somewhat similar to Buchu and Uva Ursi. It is employed with advantage in atonic amenorrhea, menorrhagia, and vaginal leucorrhcea. ACONITUM NAPELLUS. 61 ACONTTUM JSTAPELLTJS. (Aconite.) Preparation. — A tincture of the root (imported from Germany) is the strongest and most uniform preparation. It should be prepared by percolation, the strength being ounce for ounce ; though, if constantly made in the office, it will be easier to make it Sviij. to the pint, the dose being propor- tionately increased. The medium dose two-thirds of one drop, and the form of administration : 1^ Tincture of Aconite Root, gtts. xx ; Water, §iv. ; a teaspoonful every hour in acute disease, every two or three hours in chronic disease. To a child two years old the pro- portion is gtts. v. to Water giv. Aconite is a stimulant to the sympathetic system of nerves, and increases the power of the heart to move the blood, at the same time that it places the blood-vessels in better condition for its passage. It will be recollected that the same system of nerves governs the movements of the heart and of the en- tire system of blood-vessels. What will influence one, therefore, will influence the other in the same manner. But Aconite is said to be a sedative ; and by a sedative we are to understand a remedy that dimin- ishes the frequency of the pulse. How can Aconite, therefore, be a stimulant and a sedative ? There is no doubt but that Aconite is one of the most certain remedies we have to reduce the fre- 62 SPECIFIC MEDICATION. quency of the pulse in certain conditions of disease. And the condition is that in which there is a want of power on the part of the heart, and a like want of innervation to the capillary system of blood- vessels. Aconite in small doses lessens the fre- quency of the pulse, because it removes obstruction to the free flow of blood in the vessels, and gives greater cardiac power. We employ it in all forms of fever, to control the circulation, and diminish the temperature. Used in the doses named, it gives greater freedom to the circulation, at the same time that it diminishes the frequency of the pulse. It seems to remove ob- struction to the free circulation of the blood, at the same time that it removes irritation of the cardiac nerves, and gives increased power to the heart. Its action in inflammation is as pronounced as in fever. It directly antagonizes inflammatory action, and in the early stage will arrest it speedily — if this is the sedative indicated. There are some diseases of an inflammatory char- acter to which Aconite is specific, that deserve men- tion. The first of these is Tonsillitis, in which we employ it by internal administration, or better by the use of the steam atomizing apparatus. In some forms of mucous croup, with enfeebled circulation, in muco-enteritis, and in simple colitis or dy sentery from cold, I never think of making any other pre- scription. To point out the special indications for the use of Aconite I can not do better than reproduce the ACONITUAl NAPELLUS. 63 editorial iu September Journal of 1868 on the " Differential Therapeutics of Veratrum and Aconite :" To determine which of a class of remedies is applicable in a given case, is the most difficult task of the physician, and any information in this respect is of much value. I doubt whether any one using the two remedies named, would be willing to risk giving this estimate. Many may have an em- pirical intuition in regard to it, but most could ven- ture nothing but a guess. In general terms, Veratrum is the remedy in sthenia, Aconite in asthenia; but there are too many exceptions to this to make it a safe rule for our guidance. Veratrum is the remedy where there is a frequent but free circulation. It is also the remedy where there is an active capillary circulation, both in fever and inflammation. A full and bounding pulse, a full and hard pulse, and a corded or wiry pulse, if associated with inflammation of serous tissues, call for this remedy. Aconite is the remedy when there is difficulty in the capillary circulation, a dilatation and want of tonicity of these vessels, both in fever and inflam- mation. It is the remedy for the frequent, small pulse, the hard and wiry pulse (except in the cases above named), the frequent, open and easily compressed pulse, the rebounding pulse, the irregular pulse, and 64 SPECIFIC MEDICATION. indeed wherever there is the evidence of marked enfeeblement of the circulation. It is the sedative I associate with Belladonna in congestion, especially of the nerve centers, and to relieve coma. Whilst I would use Yeratrum with Gelseminum in determination of blood to the brain, and in active delirium. Veratrum act's more efficiently upon the excre- tory organs ; indeed I believe it to be one of the most certain remedies we have to increase excre- tion. Hence it is employed with great advantage for those purposes usually called alterative. Aconite controls excessive activity of the excre- tory organs, whether of the bowels, kidneys or skin. Thus it is our most certain remedy in the summer complaint of children, associated with Bel- ladonna in diabetes insipidus, with the bitter tonics and Strychnia in Phosphuria and Oxaluria, and with the mineral acids in night sweats. ACT^EA ALBA. (White Cohosh.) Preparation. — Two preparations may be used : first, a tincture of the recent root, Sviij . to Alcohol 76° Oj. ; second, a tincture of the dried root in the same proportion, but using Alcohol of 98°. Let the dose range from one to twenty drops. The White Cohosh has had but a limited use in medicine, yet it possesses such properties that it will undoubtedly prove useful when studied. The direction of experiment will be to determine its in- AGAVE AMERICANA. 65 fluence on the functions of waste and nutrition, and its special action on the reproductive organs of the female. Bloomington, III., Sept. 30. Dr. Scudder : I intended to have written to you, in regard to one specific property of the Actcea Alba. As you have reached it in your order, you can do as you wish in regard to inserting this. It is spe- cific in controlling after-pains. There is probably no remedy known that equals it. Make a tea of it, and drink freely. This power in controlling after- pains, suggests that it will prove invaluable in con- gestion and neuralgia of the womb. W. Fulton, M. D, AGATE AMEBIC AN A. (CentuPwY Plant.) The only report we have of this agent is from Dr. Penn, U. S. A., in the treatment of scurvy: " Every case has improved rapidly ; the countenance, so universally dejected and despairing in the patient affected with scurvy, is brightened up by content- ment and hope in two days from the time of its in- troduction. The most marked evidences of im- provement were observable at every successive visit. From observing the effects of the Maguey in the cases which have occurred in this command, I am compelled to place it far above that remedy which, till now, has stood above every other — lime juice. The manner in which I use it is as follows1 : The leaves are cut off close to the root. They are placed 6 66 SPECIFIC MEDICATION. in hot ashes until thoroughly cooked, when they are removed, and the juice expressed. The expressed juice is then strained, and given in doses of oij- to Siij. daily." I should be glad if some of our southern readers would try a tin^ure of the recent leaves, made by cutting them in small pieces aud covering with alcohol. We want to determine its influence on the circulation and on the nervous system. The dose would be about ten drops. AGRIMONIA EUPATORIA. Preparation. — Prepare a tincture from the fresh herb Sviij. to Alcohol 50° Oj. Dose from gtts. j. to 5ss. Agrimonia exerts a slight stimulant influence upon all the vegetative processes, and under its use we find an improvement of appetite, digestion and nutrition. It exerts a specific influence upon mucous mem- branes, checking profuse secretion, and giving tone. Thus it has been employed with advantage in cases of chronic bronchitis, phthisis with increased secre- tion, and humoral asthma. But it is especially useful in chronic catarrhal disease of the kidneys and bladder, aud will fre- quently prove curative. It gives tone and strength to these organs, and may well replace the more common tonic diuretics in nianv cases. ALNUS RUBRA. 67 ALETRIS FARINOSA. The Aletris is a gastric stimulant and improves digestion. It has also proven a valuable tonic in uterine diseases. It is deserving a thorough exam- ination, which I hope some of our readers will give it and report. Prepare a tincture from Sviij. of the root to Alcohol 76° Oj. The dose would be from two to ten drops. ALNUS RUBRA. (Tag Alder.) Preparation.— Prepare a tincture from the recent bark Sviij. to Alcohol 76° Oj. Dose gtts. j. to xx. We may employ the Alnus in infusion, or in the form of tincture with dilute alcohol ; the first being preferable if we wish its greatest influence. It exerts a specific influence upon the processes of waste and nutrition, increasing the one and stim- ulating the other. It is thus a fair example of the ideal alterative, and is one of the most valuable of our indigenous remedies. Its special use seems to be in those cases in which there is superficial disease of the skin or mucous membranes, taking the form of eczema or pustular eruption. In these cases I have employed it as a general remedy, and as a local application with the best results. It does not seem to make much dif- ference whether it is a phlyctenular conjunctivitis, an ulcerated sore mouth or throat, chronic eczema, 68 SPECIFIC MEDICATION. or secondary syphilis presenting these characteris- tics, it is equally beneficial. ALOES. The use of Aloes in medicine should be quite limited, but still it has a place. I believe that in small quantity and in combination with other agents that act upon the upper intestinal canal, it proves a good cathartic, as in the following: R Podophyllin, grs. x. ; Leptandrin, grs. xxx. ; Aloes, grs. xx. ; Extract of Hyoscyamus, 5ss. Make thirty pills. One of them at night will prove an excellent laxa- tive, and those who employ cathartics freely will like the formula. # But it is not for this purpose that I would recom- mend Aloes, but for one that may seem very sin- gular. In small doses it exerts a direct influence upon the waste and nutrition of the nervous system. In cases of feeble innervation, especially in persons of gross habit, it will be one of our best agents. I have usually prescribed it with Tincture of Nux Vomica or with Tincture of Belladonna. The dose of a strong tincture being from two to ten drops. In some cases it will prove serviceable when as- sociated with the bitter tonics, as in this : ^ Ex- tract of Nux Vomica, grs. vj.; Aloes, grs. xv. ; Hydrastine, 5ss. Make thirty pills. One may be given three or four times a day. AMMONIUM. AMMONIUM, BKOMIDE OF. The Bromide of Ammonium is a stimulant to the nerve centers ; increasing waste and improving nutrition. I have employed it principally in epilepsy, in some cases of which it is undoubtedly a specific. I do not think I can point out the exact cases in which it is likely to prove curative, as the evidences of pathological states in this disease are very obscure. Its use, therefore, will have to be empirical. I have used it now for some ten years, and it has given excellent satisfaction. But whilst it has effected permanent cures in a large number of cases, it has only proven of temporary benefit in some, and has wholly failed in others. We not unfrequently meet with disease, in which there is disordered innervation, manifesting itself as epileptiform, partially spasmodic, or in other ways, but in which there is undoubtedly the same enfeeblement of the cerebro-spinal centers. In these cases Bromide of Ammonium is the remedy. In diseases of children, I have been accustomed to employ this remedy in convulsions, following the first influence obtained by Lobelia or Gelseminum, and with marked success. When a child is subject to repeated attacks of convulsions from slight causes, the Bromide of Ammonium may be used to remove the predisposition. In some cases of whooping cough it exerts a 70 SPECIFIC MEDICATION. direct action, as it does in many cases of nervous cough in both child and adult. I have used it in this proportion : ~fy Bromide of Ammonium, 5ss. ; Water, Siv. A teaspoonful four times a day. AMMONIUM, IODIDE OF. Iodide of Ammonium increases retrograde me- tamorphosis at the same time that it exerts a stim- ulant influence upon the nervous system, especially the sympathetic system. Thus it can be employed with less risk than Iodide of Potassium, when the nutritive powers are feeble, as is the case occasion- ally in secondary syphilis. It has been employed in certain cases of persistent headache with excellent results. They are those in which the eye is dull, the face expressionless, the circulation feeble, the patient being of a full habit. The dose will be : ty, Iodide of Ammonium, 5ij- ; "Water, giv. A teaspoonful every four hours. AMPELOPSIS. The Ampelopsis comes under the general classifi- cation of alteratives. It is a feeble agent in this direction and will have but a limited use. It would be well to have it thoroughly tested, and for this purpose I would suggest a tincture of the fresh bark, in doses of from one-fourth to one teaspoonful. ANAGALLIS ARVENSIS. 71 AMYGDALUS PERSICA. (Peach Tree.) Preparation. — Thus far we have employed an in- fusion of the bark of the young limbs of the Peach Tree ; and, to a limited extent, a tincture of the re- cent bark with dilute Alcohol. The first will be found preferable in cases of acute gastric irritation ; but for ordinary office use, I would suggest the fol- lowing : Take of the green bark of the young limbs (suckers), a sufficient quantity, and cover with Alcohol 50°, one pint to each eight ounces : let it stand for fourteen days, and express — a -press of some kind will be an aid. The dose will be from five to thirty drops. The infusion or tincture, as above prepared, has a direct influence in quieting irritation of the stomach and upper intestinal canal. It is also a mild tonic, improving the functions of digestion. For these purposes it is one of the most valuable articles in the Materia Medica. It also exerts an influence upon the circulation, and upon the nervous system, which deserves inves- tigation. ANAGALLIS AKVENSIS. (Red Chickweed.) This agent possesses active properties, but has not been studied. It has been extolled in hydrophobia, 72 SPECIFIC MEDICATION. delirium, mania, epilepsy, etc., which will suggest the line of experiment. The best preparation, probably, will be a tincture of the recent Chickweed in dilute Alcohol (50°), Sviij. to the pint; dose quite small — coming within one or two drops. ANEMONE NEMOROSA. (Wood Anemone— Wind Flower.) This is also an active agent, and will probably re- pay careful study. It influences the functions of waste and repair, but acts directly upon the nervous system. Belonging to the same family as the Pul- satilla, its action will be somewhat analogous. The preparations best adapted for study will be a tincture of the recent plant, made in the proportion of §viij. to Alcohol 76° Oj.; using pressure to re- move the fluid. It will be well to commence with the fraction of a drop as a dose, say — ~fy Tincture of Anemone, gtts. x. ; Water, Siv. ; a teaspoonful every two to four hours, gradually increasing as we feel our way. APOCYNUM cannabinum. (Indian Hemp.) Preparation. — The preparation I prefer is, an alco- holic fluid extract, representing the crude article ounce for ounce. Of such fluid extract, the dose APOCYNUM CANNABINUM. 73 will vary from the fraction of one drop to ten drops, as the maximum. If the physician prepares his tincture, it should be from the recently dried root, in the proportion of oviij. to Alcohol 76° Oj. It is probable that the Apocynum Androssemifo- lium possesses identical properties, and as the dis- tinction is recognized with difficulty, even by those most conversant with botanic medicines, they have been used indiscriminately. The Apocynum is a true specific for that atonic condition of the blood-vessels, that permits exuda- tion, causing dropsy. I have employed it in my practice for some eight years, and it has not failed me in a single case, where the diagnosis was well made. It is a positive remedy for dropsy, whether it takes the form of oedema, anasarca, or dropsy of the serous cavities, where there is no obstruction to the circulation, and no febrile action. We would not expect it to effect a cure in dropsy from heart disease, or ascites from structural disease of the liver, neither would we where there was a frequent, hard pulse, and other evidences of febrile action. Still in these cases, if we can partially remove the obstruction in the first case, and after an arrest of febrile action in the second, the Apocynum will re- move the deposit. It is not worth while to inquire how it removes dropsical accumulations. It seems to strengthen the circulation, and as absorption takes place there is an increased flow of urine. • 7 74 SPECIFIC MEDICATION. I have also employed the Apocyrmm in cases of passive menorrhagia with advantage. It may be especially recommended in those cases in which the flow is constantly too profuse, too long, and too frequently repeated. I use it with water, in the following proportion : Ify Fluid Extract of Apocy- nnm, 5j- to 5ij. ; Water, giv. ; a teaspoonful every three hours. ARALIA HISPIDA. (Dwarf Elder.) The Dwarf Elder has been extensively and suc- cessfully employed in dropsy. The infusion has usually been employed, and given freely. I wonld suggest a tincture of the recent bark, in dilute Alcohol, in the proportion of gviij. to the Oj. ; dose gtts. x. to 5j- I have employed it to but a limited extent, yet with good results. It has a very positive influence on the circulation, and upon secretion. Does it not act on them through the sympathetic nervous system ? and may we not influence all the vegetative func- tions with it, as we do with some others ? It is de- serving thorough investigation. ARNICA MONTANA. (Arnica.) Preparation. — Prepare a tincture from the recent flowers, Sviij. to Alcohol 76° Oj. Dose, the fraction ©f a drop. ARNICA MONTANA. 75 It is not necessary to refer to the common local use of this agent, or discuss the question whether a tincture of Arnica is preferable to Alcohol alone as a local application. Every one has employed it in this way, and each has formed his own opinion. I think its local use valuable, but greatly over-esti- mated. Can it be employed as an internal remedy with advantage ? I am satisfied that it can. It is a val- uable stimulant in many grave diseases where a stimulant is most required. But if used as a gen- eral stimulant, like Alcohol, it would be as apt to do harm as good. It is a specific stimulant to the spinal nervous sys- tem, and will be found useful where there is want of innervation from this. I have seen most marked benefit from it in advanced stages of disease, where there was feeble respiratory power ; difficulty of sleeping from impeded respiration ; want of control over the excretion of urine and feces, etc. ; evidences of impairment of spinal innervation. In such cases its beneficial influence may be noticed in a few hours. I have frequently prescribed it for lame back, back-ache, and feelings of debility, soreness, etc., in the small of the back. It is only useful in those cases where there is feebleness, with deficient circu- lation ; but in these the influence is direct and per- manent. 76 SPECIFIC MEDICATION. ARTEMESIA ABSINTHIUM. (Wormwood.) Preparation.-^-F or experiment, I would suggest a tincture with dilute Alcohol, 76°, in the proportion of Sviij. to the pint; vary the dose from one drop to one drachm. This agent has been used principally as a vermi- fuge, but lately it has given place to the«Chenopo- dium, and to Santonine. It possesses very decided medicinal properties, however, and deserves a thor- ough examination. It influences the nervous sys- tem, especially the sympathetic. ARTEMESIA SANTONICA. (Wormwood.) We only wish to consider the cry stalliz able prin- ciple— Santonine — here. Its principal use has been as a vermifuge in cases of ascaris lumbricoides, for which it has been found quite efficient. But in using it for this purpose many have noticed that it exerted a peculiar influence upon the brain, and upon the eyes — rendering objects blue, yellow, or green ; and that it passed off in the urine, giving it a peculiar color. _ It exerts a specific action upon the bladder and urethra, stimulating contraction of the -first, and allaying irritation of the second. It is especially valuable in cases of retention of the urine in chiU dren during protracted disease ; in doses of half to ASCLEPIAS TUBEROSA. 77 * one grain, it is prompt and certain. I have also employed it to relieve irritation of the urethra, es- pecially in women suffering from uterine disease, and with good success. Its influence upon the nervous system needs to be studied. I judge it to be a nerve stimulant, and have employed it for this purpose to a limited extent. ASCLEPIAS. (SlLKWEED.) Preparation. — The best preparation for experi- ment will be a tincture of the recent root, in the proportion of Sviij. to Alcohol 76° Oj. ; note its effect in small as well as large doses. The A. Incarnata, A. Syriaca, etc., deserve a care- ful investigation. In weak infusion they all prove diaphoretic, and to some extent diuretic. It is claimed by those who have made considerable use of them, that they stimulate all the secretions. ASCLEPIAS TUBEROSA. (Milkweed.) Preparation. — Whilst I prefer a tincture made as above, I have used the alcoholic fluid extract of the dried root, made to represent ounce for ounce ; the dose beiug from one drop for a child two years old, to ten drops for an adult. It is especially a child's remedy, being feeble in action, though quite certain. When given freely, 78 SPECIFIC MEDICATION. it is one of the most certain diaphoretics we have, providing the pulse is not frequent, and the tempera- ture increased. Even in the small dose of one drop, following the use of the special sedatives, it will markedly increase true secretion from the skin. Recollect that there is a difference between* sweating and secretion. There may be a profuse exudation of water, the surface being bathed in perspiration, and yet but little secretion. Excretion by the skin is a vital process, and takes place by means of secreting cells. It goes on best where the skin is soft and moist, and not when covered with drops of sweat. I employ Asclepias in diseases of children, believ- ing that it allays nervous irritability, is slightly se- dative, and certainly increases secretion from the skin. I use it with Yeratrum and Aconite, in febrile and inflammatory diseases, and in mild cases, very frequently give it alone. Bear in mind that it is a feeble remedy and too much must not be expected. ASPIDIUM FILIX MAS. (Male Fern.) This agent is only used as a vermifuge, especially for the removal of the tapeworm. For this purpose the Ethe*v>al Oil is used in doses of twenty drops to one drachm. ATROPA BELLADONNA. 79 ASAFCETIDA. Whilst I think but little of the foetid gum as an antispasmodic, I regard it as a valuable gastric stim- ulant, and also as a nerve stimulant. In nervous dyspepsia, especially, it will be found valuable. The following is a good form : 1^ Asafcetida, 5ss. ; Hydrastine, 3ss. ; Aloes, grs. x. Make thirty pills, and give one three times a day. As a nerve stimu- lant I have used : Ify Extract of Nux Vomica, grs. x. ; Aloes, grs. xl. Make twenty pills, and give one at night. ATROPA BELLADONNA. (Belladonna.) Preparation. — Whilst for some purposes a solution of the Alkaloid Atropia will prove the best prepara- tion, I prefer for general use an Alcoholic fluid ex- tract of the recent plant, representing the crude article ounce for ounce. Of this the maximum dose will be one drop, but frequently one-fifth to one- half of this will serve a better purpose. For hypodermic use, we employ a solution of Atropia, in the proportion of one grain to the ounce of distilled water. The dose would be fi.ve to ten drops. This is also the best proportion for use to dilate the pupil. As a collyrium, we would add 5j- of this solution to §j. of distilled water. The specific use of Belladonna is as a stimulant to the capillary circulation, especially of the nerve 80 SPECIFIC MEDICATION. centers — a remedy opposed to congestion. My at- tention was first drawn to it by an article from Brown-Sequard, giving the results of his experi- ments with the drug, stating that with the micro- scope he had seen marked contraction of the capil- laries following its use. It at ouce suggested itself to me, that if it would cause capillary contraction, it would be the remedy for congestion ; and I at once commenced experimenting with it in this direction. I well recall my first marked case : a boy about eight years old, suffering from malignant rubeola. The entire surface was swollen and dusky ; the eyes dull ; the pupils dilated ; the face expressionless ; breathing labored, and wholly unconscious forforty- ei°rht hours. The administration of Belladonna alone (in small doses) was sufficient to restore con- sciousness, and a free circulation, with good appear- ance of the eruption, in twenty hours. The evidences in its favor rapidly accumulated, so that in eighteen months I used it with a feeling of almost certainty for this purpose. Whilst it exerts the same influence on all persons, and at all ages, the true pathological condition being determined, it is especially valuable in treating dis- eases of children. In the young, the immature ner- vous centers suffer more severely, and we find the opposite conditions, of irritation with determination of blood, and atony with congestion. The symptoms calling for the use of Belladonna are usually very plain : the patient is dull and gtupid — and the child drowsy, and sleeps with its ATROPA BELLADONNA. 81 eyes partly open ; the countenance expressionless ; the eyes are dull, and the pupils dilated, or immo- bile ; whilst, as it continues, respiration becomes affected, and the blood imperfectly aerated. In these cases I prescribe Belladonua : in the adult, in the proportion of gtts. x. to gtts. xx., to Water giv. ; in the child gtts. v. to 5iv. ; in each a teaspoonful every hour. As these are mostly febrile cases, or at least have a feeble, frequent circulation as au element, I give Aconite in the usual doses. Belladonna is also a specific in incontinence of urine. Kot that it will cure any case, but those in which an enfeeblement of the pelvic circulation is the principal cause. Probably a lesion of the spinal cord has also much to do with it. Of course, it gives no relief where the incontinence arises from vesical irritation. The dose in this case will be the same as above named, but only repeated four times a day. Belladonna is also a specific in diabetes insipidus ; even a Belladonna plaster across the loins being sufficient in many cases for its arrest. Belladonna is undoubtedly a prophylactic against scarlatina, as I have thoroughly proven in my prac- tice. Recollect, however, that it is only prophylac- tic in small doses ; in doses sufficient to produce dilatation of the pupil, it has no such influence. Belladonna has other special uses, but they may be briefly summed up : if in any case there is an enfeebled circulation, with stasis of blood, Bella- donna is the remedy. Of course, acting upon some 82 SPECIFIC MEDICATION. parts more directly than others, its influence will be more decided, but there is no case, with condition as above, in which it will not be beneficial. I may say in conclusion, that we want a good preparation of the recent herb ; and then it must be used in small doses to obtain the influences named. The doses given are the maximum. As we have had occasion to say before, the druggists care little about the quality of medicines sold ; they are simply articles of merchandise, and there is little, if any, professional esprit with them, to aid us in having them good. Therefore every physician must be on his guard when purchasing, and had better buy of first hands, and of those of proven honesty. APIS MELLIFICA. (Honey Bee.) The Honey Bee possesses marked medicinal prop- erties, but from a prejudice against such remedies, has been but little employed. An infusion of twelve to twenty Honey Bees in a pint of boiling water, is .one of the most certain diuretics I have ever employed in cases of suppres- sion of urine from atony. It is also a very efficient remedy in retention of urine, and in some cases of irritation of the urethra. I have used a tincture for the same purpose, and also for inflammation of subcutaneous structures, with tensive and lancinating pains, and in irritation of the skin. I have prepared my own tincture, in AGARIC. 83 the proportion of §j. to Alcohol 98° Oj. Dose one to two drops. AGARIC.* History. — This is obtained from various fungus plants of the mushroom tribe. These plants afford a great diversity of form and structure, being in their simplest character little articulated filaments, composed of chains or cellules, as in the mildew of the rosebush, and in moldiness, mucor ; again, they may present an even and imperforate surface, and another separated into plates or cells, in which the sporules are deposited. They absorb a great amount of oxygen with evolution of hydrogen and carbonic acid gas, and contain considerable propor- tions of nitrogen. They are destructive to nearly all organic matter upon which they grow. Accord- ing to Dr. M. A Curtis, of K". C, the genus boletus, as now constituted, includes only fleshy species, with a hymenium composed of sporable tubes. Those species formerly included in Boletus, and whose hymenium is composed of yores, now form the genus Polyporus." The Polyporus Officinalis {Boletus Laricis), known by the name of White Agaric, Purging Agaric, etc., is procured from Asia, Corinthia, Russia, Central America, and the Rocky Mountains, where it is found growing upon the Larch. It is in masses, *The following is taken from the new edition of King's Ameri- can Dispensatory. 84 SPECIFIC MEDICATION. varying from the size of an ordinary apple to that of a large nutmeg-melon ; its shape somewhat re- sembles a horse's hoof; it is reddish-gray or yellow externally, whitish internally, and of a spongy, fri- able consistence ; hymenium concrete ; substance of the pileus consisting of snbrotund pores, with their sim- ple dissepiments ; pileus corky-fleshy, ungulate, zoned, smooth ; pores yellowish ; it has a feeble odor, and a bitter, acid, somewhat sweetish taste. Braconnot found in it 72 parts resinous matter, 2 bitter extractive, 26 of a nutritious animalized prin- ciple, which he termed fungin. Benzoic acid and several salts have likewise been found in it. It is collected in August and September, deprived of its outer covering, and then dried and placed in the sun. The Polyyorus {Boletus) Ignarius, Agaric of the Oak, is a fungus found on the oak, cherry, wallow, plum, and other trees ; when young it is soft, but gradually becomes hard and woody. In shape it somewhat resembles the preceding ; its upper smooth surface is marked with dark circular ridges, and its under is very porous, and of a yellowish-white color. It is tasteless and inodorous. The Polyporus (Boletus) Fomentarius, growing on similar trees with the P. Ignarius, when cut in slices, beaten, soaked in a so- lution of nitre, and dried, forms an inflammable substance, known as Spunk, Amadou, or German Tinder. The Polyporus Pinicola grows upon the pine, birch, tamarac, fir, and similar trees ; with ab- solute alcohol the fresh fungus forms a dark-red, AGARIC. 85 intensely bitter tincture. A white amorphous pow- der, called laricin, is obtained from some of these plants. It has a bitter taste, is soluble in alcohol and oil of turpentine, forms a paste with boiling water, and has the formula C14H1204. Properties and Uses. — The dust of the Larch Agaric is irritating to mucous surfaces, causing tears when it enters the eyes, and sneezing, cough, and nausea, when the nostrils are exposed to it. It has been used in half-drachm or drachm doses as a purgative ; in larger doses as an emetic. In doses of from three to ten grains, gradually in- creasing to sixty grains in the course of the twenty- four hours, it has been found efficacious in arresting the nocturnal perspiration of consumptives. Ex- ternally, it has been used, together with the Agaric of the Oak, as a styptic, and said to restrain not only venous but arterial hemorrhages, without the use of ligatures. It does not appear, however, to possess any real styptic power, or to act otherwise than dry lint, sponge, or other soft applications. Pre- pared with nitre, as for tinder, it has been used as a species of moxa. The P. Officinalis and the P. Pinicola, in doses of from three or four grains of the powder, repeated every three or four hours, or of the concentrated tincture in doses of five drops, have both been found valuable in the cure of obstinate and long standing intermittents, and other diseases common to mala- rial districts ; as, obstinate bilious remittent fever, chronic diarrhoea, chronic dysentery, periodical neu- 86 SPECIFIC MEDICATION. ralgia, nervous headache, ague cake, and increased flow of urine. They have likewise proved useful in long standing jaundice, and in the chills and fever common among consumptive patients. The tincture of Boletus exerts a marked influ- ence upon the spinal and sympathetic nervous sys- tem, in certain cases of disease. It has been suc- cessfully employed in the treatment of epilepsy and chorea, and to check the rapid pulse with hectic fever and night sweats in phthisis. It has also been recommended in insanity where there is a feeble cerebral circulation and imperfect nutrition. And, also, in neuralgia, with similar symptoms. BAPTISIA TINCTORIA. Preparation. — The Baptisia has been principally employed in infusion, and I am well satisfied that this is the best preparation for general use. Still, as it will be inconvenient in many cases, I would re- commend in addition, a tincture by percolation, using Sviij. of the ground bark to Oj. of Alcohol of 76°. Of an infusion of 5j. to §iv. of boiling water, the dose is one teaspoon ful ; of the tincture as named, 5ij- to Water, giv., dose, a teaspoouful. "With some the Baptisia has been a favorite rem- edy for sore mouth and sore throat, using it locally, and for this purpose it is one of the most valuable remedies we have. I judge, however, tbat if you should ask, in what particular variety of sore mouth BAPT1SIA TINCTORIA. 87 or throat it was found best ? you would have diffi- culty in getting an answer. It is in those cases in which there is enfeebled capillary circulation, and tendency to ulceration, that it is specific. That is, the condition is one of atony, with tendency to molecular death and de- composition. The remedy is, therefore, stimulant and antiseptic. It may be employed with the greatest certainty in any form of sore mouth or throat presenting the characteristics named. Especially in stomatitis ulcerata, or cancrum orris, in cynanche maligna, and in the sore throat of scarlatina maligna ; but it is not only a good local application in these cases, but a most valuable internal remedy. It is specific to the condition upon which such sore mouth and throat is based, whether it is manifested in this way, or in ulceration of Peyer's follicles in typhoid fever. Thus I have employed it with very marked advantage, in all cases showing putrescency, and tendency to softening and breaking down of tissue. It is not a remedy for acute inflammation, whether erythematous or deep seated, and in ordinary stom- atitis or cynanche, it is not a remedy. In diphtheria presenting acute inflammatory symptoms, it is worse than useless. But in diphtheria with swollen and enfeebled mucous membranes, dusky or livid discoloration, or blanched appearance, with ten- dency to ulceration and sloughing, there is no remedy more certain. 88 SPECIFIC MEDICATION. I have successfully employed the Baptisia in typhoid dysentery, as have others. But as will be seen, this is hut the condition named above for its specific action. So long as there is an acute in- flammation, with stools of blood or pure mucus, this is not beneficial, but when the discharges re- semble "prune juice, the washing of meat, or are muco-purulent," with general symptoms of an an- alogous character, then it becomes one of our most certain remedies. BENZOIC ACID. I prefer to use Benzoic Acid in solution in Alco- hol, 5j- to the Oj. to the tincture of Benzoin, though the latter will answer the purpose. The dose will vary from ten to sixty drops, according to the effect lesired. Its first use is in irritable bladder, with deposits of uric acid or triple phosphates ; in either case its use will prove beneficial. Its second use is in irritation of the sympathetic and spinal system of nerves, with uric acid deposits. Its third use is as a stimulant to the brain in cases of exhaustion with Phosphuria. I have used it in this case alternated with a preparation of Phosphorus — either the Phosphuretted, Oil or the Tincture — with advantage. These are usually cases of exhaustion from over-exertion of the mind, as frequently met with among our business men. BEBEERINA SULPHAS. 89 BERBERIS VULGARIS. (Barberry.) A tincture of the recent bark, in the proportion of 5viij. to Alcohol 76° Oj., is suggested. Dose varying from ten drops to one drachm. Will some of our Eastern practitioners give us their experience with this agent ; or if it has not been employed alone, will some one test it thor- oughly. Evidently it has an influence upon the gastro-intestinal mucous membrane, and probably on associate viscera. BEBEERINiE SULPHAS. This is not the so-called Berbeerin from the Ber- beris Vulgaris, but a well-defined salt from the !Nec- tandra Rodisei. As found in commerce, it is in glit- tering scales of a brownish-yellow color, and when triturated forms a yellowish powder. It exerts a specific action upon the uterus, but thus far it has been principally employed in cases of menorrhagia. In this case its influence is very marked, controlling the hemorrhage, and prevent- ing its recurrence. As we have other remedies for the milder cases, its use might be confined to those in which there is profuse discharge at each men- strual period, and where they recur too frequently. The dose will be from two to three grains every three or four hours. 8 90 SPECIFIC MEDICATION. BISMUTH. "We employ Bismuth in two forms. The sub- nitrate in doses of from one to two grains ; the liquor Bismuth (solution of Citrate of Bismuth), in doses of from gtts. x. to 5j- The first use of Bismuth is to allay irritation of the gastro-intestinal mucous membrane ; and for this purpose it has been extensively employed. Usually the sub-nitrate in impalpable powder, is employed in small doses frequently repeated for gastric irritation, and in doses of Hive to ten grains for intestinal irritation, with diarrhoea. The second may be called its specific use, for chronic gastro-intestinal irritation, or dyspepsia with diarrhoea. Here I employ the Liquor Bismuth in doses of from a half to one teaspoonful four times a day. In inveterate cases, not amenable to treatment, and of years duration, I have had the happiest results. I have omitted to name the common use of Bis- muth for water-brash, in some cases of which it is very effectual. The powdered sub-nitrate is also the most effec- tual local application for irritation of the skin — chafing — either in the infant or adult. For this pur- pose the part is thoroughly dusted, and it is re- peated as often as necessary to keep it dry. BROMIDE OF POTASSIUM. 91 BROMINE. Bromine is not employed as an internal remedy, though its salts have been used largely within the last ten years. It may be employed with advantage as an inhalation in croup and diphtheria, and as a stimulant in phthisis. For croup it has been used in the proportion of ten drops to two ounces of water. BROMIDE OF POTASSIUM. Bromide of Potash is a very greatly overestimated remedy. When I commenced practice it was only used in cases of spermatorrhoea to relieve sexual irritation — now it is recommended for everv nervous ill that flesh is heir to. I think it has one specific use, and that is as a remedy for epilepsy when associated with irritation of the reproductive organs, or especially in irritation of the cerebellum. In such cases I have used it with much success. The dose will be about twenty grains three times a day. I only use it in spermatorrhoea, in those cases in which the person is of a plethoric habit, with great venereal excitement — cases approximating satyri- asis, rather than spermatorrhoea. In these I ad- minister it in doses of thirty to sixty grains at bed- time. 92 SPECIFIC MEDICATION. BIDENS BIPINNATA-CONNATA-FBONDOSA. (Spanish Needles.) Prepara Hon.— Prepare the tincture from the recent herb, in the proportion of oviij. to Alcohol 76° Oj., using pressure. Dose from five to thirty drops. The different varieties of Bidens deserve investi- gation. Reference to the Dispensatory or Materia Medica will give the direction it should take. I am especially interested in the action of the B. Fron- dosa on the heart and circulation. BRYONIA. This remedy is extensively employed by the Homoeopaths ; and, as I think, greatly overestimated. They use it in rheumatism, pneumonia, and other diseases of the chest; in typhoid fever, and many other affections. It may be recommended for in- vestigation— Ify Tincture of Bryonia, 3ss. ; Water, §iv. ; a teaspoouful every one or two hours. BRAYEBA ANTHELMINTICS This agent is only employed as a remedy for tape- orm ; and when of good quality it is very efficient. CALENDULA OFFICINALIS. (Marigold.) A tincture of Calendula has been employed by the Homoeopaths as a local application in wounds ; but without any advantage that I have been able to see. worm CAMPHOR. 93 CALX. (Lime.) Lime is used for the ordinary purpose of an antacid, and in some cases is preferable to any other alkali. This is especially the case in indigestion, with the formation of lactic acid from decomposing food. Here there is not unfrequently an excess of the normal salts of the blood, and we can not use the salts of soda and potash to neutralize gastric acidity. It may be stated, as a general rule, that it will be found beneficial in cases of infantile dyspep- sia, and in dyspepsia of the adult, with acid eructa- tions during digestion. Its specific use is in cases of furunculus or boils, and other inflammations of cellular tissue, terminat- ing in suppuration. Why it has this specific influ- ence I do not propose to say, but the fact I have proven in scores of cases. Given a case in which boils are being continually developed, the use of lime water will effect a radical cure. It is given in doses of a wineglassful three or four times a day. CAMPHOR. Camphor in small doses is a stimulant, in large loses a sedative, to the nervous system. I do not regard it as having a very extended use in medicine, though for the purpose named, it may sometimes be employed with advantage. In low forms of dis ease, with insomnia and restlessness, I have used it 94 SPECIFIC MEDICATION. alone, and in combination with stimulant doses of Opium or Morphia, and Quinine. As a topical stimulant, it may be employed with advantage, when the integrity of the part is threat- ened from enfeebled circulation. CANNABIS SATIVA. (Hemp). The tincture of Cannabis should be prepared from the recent wild plant whilst in flower, but as we can not get this, we use a tincture prepared from the churrus, a species of extract from the recent plant, imported from India. The dose will vary from one to Hve drops. In small doses it is stimulant to the cerebro-spinal centers ; in large doses it produces intoxication, and finally arrest of function. It exerts an influence upon the urinary and reproductive apparatus that may be rendered available in practice, and also to some extent upon the skin. I have employed the Cannabis specially to relieve irritation of the kidneys, bladder and urethra. It will be found especially beneficial in vesical and urethral irritation, and is an excellent remedy in the treatment of gonorrhoea. I do not like it as a remedy for intemperance, (chronic alcoholism), so well as a combination of !Nux Vomica and Iodine, with a bitter tonic ; though in some cases it may be used with marked advan- tage, and the habit finally broken up by its use. CACTUS GRANDIFLORUS. 95 CANTHAKIS VESICATORIA. (Spanish Fly.) I object to the use of the blister, as a means of counter-irritation, and going further than this, I ob- ject to counter-irritation as a means of cure, when it can possibly be avoided, and I think it may be avoided in nearly all cases. As an internal remedy, Cantharis will have but one use — as a stimulant to the urinary apparatus, especially the bladder. For this purpose it may be employed in small doses. CACTUS GRANDIFLORUS. (Night-Blooming Cereus.) Preparation. — We prepare a tincture from the recent plant, in the proportion of §iv., to Alcohol 98° Oj. The dose will vary from one to ten drops. The influence of Cactus seems to be wholly ex- erted on the sympathetic nervous system, and espe- cially upon, and through the cardiac plexus. It does not seem to increase or depress innervation, (neither stimulant, nor sedative,) but rather to influ- ence a regular performance of function. I am satis- fied, however, that its continued use improves the nutrition of the heart, thus permanently strengthen- ing the organ. It has a second influence, which is of much importance to the therapeutist. It exerts a direct influence upon the circulation and nutrition of the brain, and may thus be employed with advantage in some diseases of this organ. We can see very 96 SPECIFIC MEDICATION. readily how this may be. The cardiac nerves are derived from the upper part of the sympathetic, and judging from the anatomy of the part, the first cervi- cal ganglion being the principal nervous mass in the cervical region, must furnish innervation through the cardiac nerves, as it certainly controls the circu- lation and nutrition of the brain. The Cactus is a specific in heart disease, in that it gives strength and regularity to the innervation of the organ. Its influence is permanent, in that it in- fluences the waste and nutrition of the organ, in- creasing its strength. It exerts no influence upon the inflammatory process, and hence is not a rem- edy for inflammatory disease. Feelings of weight and pressure at the prsecordia, difficult breathing, fear of impending danger, etc., are at once removed. Such irregularity of action, whether violent, feeble, or irregular, as is dependent upon the innervation, is readily controlled. Thus, in the majority of cases of functional heart disease it gives prompt relief, and, if continued, will effect a cure. In those cases in which there is another lesion acting as a cause, as in some gastric, enteric, or uterine lesions, these must receive attention, and be removed to make the cure radical. *En structural heart disease, the first use of reme- dies is to relieve the distressing sensation in the region of the heart, and the unnatural fear of danger which attends them. As these spring from disordered innervation, in the majority of cases, the Oactns gives prompt relief. As we have seen above, CAPSICUM. 97 its continuance favors normal waste and nutrition, as well as regular action. Hence, its continued use is followed by the removal of adventitious tissue ; and an increase in the strength of its contractile fibre. Hence, it is really curative in many cases of structural heart disease. I have some cases on my case book, of such aggravated form, that no one would believe they could live a twelvemonth ; yet, after a lapse of five years, they are enjoying comfortable health. But it will not relieve or cure cases of valvular deficiency, dilatation of the openings of the heart, or fatty degeneration. It is well, in estimating its action, to bear this in mind. In its influence upon the nervous system, it more nearly resembles Pulsatilla ; giving relief in that condition known as nervousness. But farther than this, it gives regularity of cerebral function, and permanently improves nutrition of the nervous centers. CAPSICUM. (Cayenne Pepper.) Capsicum is a powerful topical stimulant ; but its general influence is feeble. As Capsicum, it never gains admission to the circulation, and, in the pro- cess of digestion, it almost wholly loses its proper- ties as a remedy. Capsicum is used as a topical stimulant to the skin, and with advantage where the circulation is feeble, and there is need of such stimulation. It 9 98 SPECIFIC MEDICATION. also exerts the revulsive influence of other rube- facients. Its influence, when taken into the stomach, is of the same character. It excites the nerves, and calls an increased flow of blood to the part. In torpid states of the gastric mucous membrane, such action may be very desirable, may even be essential to life : as, in congestive intermittent. It is the topical action upon the gastric mucous membrane that is beneficial in some cases of delirium tremens. The solar plexus, the most important of the vege- tative nerve centers, may be thus influenced from the stomach. The stimulant influence of Capsicum may, therefore, be extended through this, and be of marked advantage in states of great and sudden prostration with tendency to congestion. CAKBO-LIGNI. (Wood Charcoal.) Is an absorbent and antiseptic, and has this gen- eral use, both internally and topically. Given in water-brash , or where there is decomposition of the food, it is sometimes quite beneficial. So in topical disease — with free secretion and tendency to sepsis — its local application absorbs the one and checks the other. The specific use of charcoal is to arrest hemor- rhage from the bowels. It is used in enema, 5j. to 5ij. finely powdered, to four ounces of water, thrown CAULOPHYLLUM. 99 up the rectum.' Why it checks it I can not tell ; that it does it, I have the evidence of my own eyes. CASSIA ACUTIFOLIA. (Senna.) Senna is a mild cathartic; but its action is fre- quently attended with much tormina, and to some is very unpleasant. As it does not increase elimi- nation by the bowels, its use as a cathartic is quite limited, and it may well be replaced by other remedies. It exerts, however, a special influence in colic, which renders it an important remedy. We have generally employed it in the form of the Compound Powder of Jalap and Senna, in doses of &ve or ten grains, frequently repeated until relief is obtained. An infusion of Senna — or the tincture will answer the same purpose — for the relief of colic, whether the common wind-colic or that known as bilious, I regard as one of our best remedies. CAULOPHYLLUM. (Blue Cohosh.) We employ this remedy in infusion as a parturi- ent, and in the form of a tincture of the recently dried root, §viij. to Alcohol 76° Oj. The alcoholic fluid extract, representing ounce for ounce, is also a good preparation. Caulophyllum exerts a very decided influence 100 SPECIFIC MEDICATION. upon the parturient uterus, stimulating normal con- traction, both before and after delivery. Its first use, in this case, is to relieve false pains ; its second, to effect co-ordination of the muscular contractions • and third, to increase the power of these. The first and second are the most marked, yet the third is quite certain. Still if any o*ne expects the marked influence of Ergot, in violent and continued con- tractions, he will be disappointed. I judge that it exerts its influence through the hypogastric plexus ; though to some extent it influ- ences every process controlled by the sympathetic. Acting in this way it influences the circulation, nu- trition, and functions of the reproductive organs. I have employed it in chronic uterine diseases with some advantage ; but further study is necessary to point out the particular cases. It may be used with good effect in some cases of nervous disease; especially in that condition known as asthenic plethora. As a remedy for rheumatism it is inferior to the Macrotys, but in some cases it exerts a better influ- ence. My experience has not been sufficient to point out these cases, and in this respect the remedy needs further study. I would suggest, also, the trial of a tincture of the recent root. CHIMAPHILLA UMBELLATA. 101 CEANOTHUS AMERICANUS. (Redroot.) This agent deserves investigation, as it possesses marked medicinal properties. The direction of ex- periment may be judged by reference to the Dis- pensatory. Use a tincture of the recently dried root, in doses of 30 to 60 drops. CELASTRUS SCANDENS. (False Bittersweet.) This belongs to the class alterative. It has no special action that I am aware of, though it might be studied with advantage. CHELONE GLABRA. (Balmony.) The Chelone exerts an influence on waste and nutrition, and deserves study. We would prepare a tincture from the recent leaves, by expression, in the proportion of Sviij. to Alcohol, 76° Oj. Dose, ten to thirty drops. CHIMAPHILLA UMBELLATA. (PlPSISSEWA.) The Chimaphilla has been used mostly in infu- sion or decoction : but for general use it may be prepared in the form of tincture, both of the recent and the dried leaves — though they will differ mate- 102 SPECIFIC MEDICATION. rially in strength and properties — the fresh leaves possessing a volatile principle which is lost in drying. The Chimaphilla has been principally employed as a tonic diuretic, influencing the urinary apparatus in a similar manner to the Buchu and Uva-Ursi, though I think it preferable to either. It relieves irritation of the entire urinary tract, and improves the circulation and nutrition of these organs. It also influences the processes of waste and nutrition, and possesses the properties termed alte- rative. In this respect it has not been thoroughly studied, though highly spoken of by some in the treatment of scrofula and secondary syphilis. CHIONANTHUS VIKGINICA. (Fringe-Tree.) This agent comes to us with the recommendation of Dr. I. J. M. Goss, of Georgia, who says : " It possesses important alterative properties. As a catalytic, it has the most decided influence over the glandular system of any article I have tried. It pervades the whole system, combining with the materies morbi, and conveying it out of the system. I have used it in mercurial cachexy with the most happy success, in quite a number of instances. But the most important therapeutical property that it possesses, is its specific power over morbid condi- tions of the liver. I have tried it in hypertrophy of that organ, and with uniform success ; and also in obstruction of the liver, in malarious districts, CHLOROFORM. 103 with like success. Some years ago I called the at- tention of the profession to its specific effects in jaundice, and gave several cases in proof of the fact. Since then I have used the Chionanthus in a great many cases of jaundice, and have never failed to re- move it in but one single case, and that one I think was a case of obstruction of the gall ducts by cal- culi ; in that case, I tried all the reputed cholagogues, without success. It removes jaundice of years standing, in from eight to ten days. I have treated several persons that had been subject to jaundice, annually, in summer, for several years, and had been dosed with blue pill, calomel, and other articles, without any benefit, and I have not failed in a single instance, to remove the disease entirely. And when it is relieved with the Chionanthus, it does not return ; at least it has not, in any instance to my knowledge. It is as near a specific in jaun- dice, as quinine in periodicity. The mode in which I have used it is to make a tincture of the bark of the root in gin, say §ij. to the quart of gin, and give gss. of this every three hours, or the fluid ex- tract, and give from one to two drachms every three hours." CHLOROFORM. Chloroform by inhalation exerts a specific influence upon the cerebral center, arresting its power to re- ceive impressions — a condition known as ansesthesia. If carried still farther, it influences the spinal center 104 SPECIFIC MEDICATION. in the same manner, and arrests automatic move- ment— respiration. This action is so well known, that it is not worth while occupying our space with it. Administered hy mouth, in small doses, it is a cerebral stimulant; in large doses, it lessens con- sciousness, the effect being more like poisoning by Alcohol, than the anaesthetic influence from its in- halation. In small doses (gtts. x. to 5j«) it is successfully employed to arrest convulsions. The small doses are safe, but it will not do to repeat it often in the larger quantity named. It is also used to relieve gastro-intestinal pains, especially in the form of common colic. In cases of biliary calculus it is used as a prophy- lactic, preventing the deposit of cholesterin, and causing its solution when deposited. For this pur- pose it is used in doses of gtts. xx., three times a day. CHLORAL HYDRATE. The introduction of this new remedy has been attended with the same enthusiasm displayed in the case of Bromide of Potassium. It is evidently good for something, but what, has not yet been satisfac- torily determined. It is a hypnotic, and may be employed for this purpose, where there is an enfeebled condition of the brain, with impaired nutrition. It relieves pain, CHLORAL HYDRATE. 105 when the nervous centers are suffering from im- paired circulation and irritation, and maybe advan- tageously employed in these cases. It has been successfully employed in the treat- ment of delirium tremens, but in some cases it has failed. I have not used it for this purpose, but ap- plying the above principles would conclude that it is a remedy only in those in which the nervous centers are suffering the exhaustion of over stimula- tion, and not in those in which there is irritation and determination of blood. These cases require opposite remedies, and if I am correct in the view I have taken of the action of Chloral, it will doubtless prove a very important remedy. The remedy also suggests itself as one adapted to allay irritation and produce sleep in a majority of cases of puerperal mania. Dr. Playfair reports a case in which it was used with excellent success. I am satisfied from its action that it will prove a boon to the opium eater who desires to break off the destructive habit. Whilst its influence upon the nerve centers is the same as stimulant dose3 of Opium, and will thus give present relief, it gives strength to the cerebral circulation, and will thus favor normal nutrition ; then the dose can be les- sened, and finally the remedy dispensed with. To give the estimate in which the drug is now held, I quote from the London Lancet : " This interesting drug has now been sufficiently tested by a large number of eminent practitioners to enable us to form a tolerably clear idea both of 106 SPECIFIC MEDICATION. its merits and its defects ; and as we perceive that (after the usual fashion in matters medical) there is going to be an epidemic rage for the new remedy, it may he well to call the attention of the public to the principal features of its action which can be said to be fairly made out. " In the first place, the term ' anesthetic " should no longer be applied to chloral, for it has entirely failed to make good its claim to this reputation ; even the largest doses do but produce a heavy and prolonged sleep, which is, however, essentially dif- ferent from true anaesthesia. On the other hand, as a producer of sleep, Chloral is, in many respects, unrivaled ; for though, like every other remedy, it fails in a considerable number of cases, it does suc- ceed in a very large number ; in fact, it is inferior in certainty, as a hypnotic, to Opium alone. More- over, it is very greatly superior to Opium, and almost every other drug, in the character of its sleep-producing action; there are no attendant symptoms of cerebral oppression; the sleep, though often prolonged, is light and refreshing, and no un- pleasant after-symptoms are experienced. It is im- portant to observe, however, that this description only applies to the use of moderate quantities, and that not only unpleasant but highly dangerous symptoms have been produced by doses which we regret to see are very commonly used. Very careful inquiry leads us to assert that it is both unnecessary and dangerous to give larger doses than twenty to thirty grains, repeated once or twice if necessary, CHLORAL HYDRATE. 107 for hypnotic purposes. Doubtless it might happen that 100 consecutive patients might take much larger doses with impunity, but the 101st might present the alarming symptoms described by Dr. Reynolds, in a recent number of the Practitioner, as produced by a dose of fifty grains, and these symp- toms might easily take a fatal turn. " As a remedy for pain, Chloral holds a very varying place in the estimation of medical men, some rating it highly, and others thinking it almost worthless. Perhaps the safest estimate of its power over pain is that it only exerts an indirect influence by inducing a disposition to sleep, in which the pain is forgotten. Certainty it has entirely failed, in the hands of the present writer, to relieve severe pain of a pure neuralgic type. On the other hand, there is a good deal of evidence that it relieves suffering where the parts are very tense, and where mere arte- rial throbbing counts for much in the production of pain ; thus it has been very favorably spoken of for its effects in gout. And this fact, if it be correct, corresponds with certain observations which have been made as to its action on the circulation. Both from sphygmographic experiments on healthy per- sons and on patients, and also from the details of the nearly fatal case reported by Dr. Reynolds, there is reason to think that Chloral exerts a contracting influence upon the arteries, powerful in proportion to the dose ; and it may well be that arterial throb- bing is checked by this kind of influence, " On the whole, however, there can be little doubt 108 SPECIFIC MEDICATION. that the great function of Chloral is that of a hyp- notic and calmer of general nervous irritability. In delirium tremens it is excellent : and it is prob- able that with two such weapons for choice as Bro- mide of Potassium and Chloral we shall be able almost entirely to dispense with the use of Opium, which is so uncertain and dangerous a remedy in that disease. In the state of sleeplessness which threatens the access of puerperal mania, Chloral is probably an unequaled remedy. In melancholia its action as a hypnotic appears to be powerfully and remarkably sure. In mania , also, it acts well enough as a hypnotic, though there seems some division of opinion as to whether it does permanent good. We may also state that in the irritable con- dition of aged persons who find it difficult to sleep for any length of time continuously, the use of a single dose of thirty grains of Chloral appears often to answer excellently well. The minor uses of the drug in relieving more trivial conditions of nervous irritation, and in alleviating painful spasmodic symptoms of various kinds, are probably consider- able." CINCHONA.— (See Quinia.) CISTUS CANADENSIS. (Rock-Rose.) Preparation. — A tincture is prepared from the recent plant, in the proportion of §viij. to Alcohol 76° Oj. The dose is from ten to thirty drops. CINNAMON. 109 The Cistus has a direct and positive influence on the processes of waste and nutrition, and hence possesses the properties known as alterative. It has been used with especial advantage in scrofula, and in chronic diseases dependent upon an enfeebled nutrition, or deposit of imperfectly formed plasma. It is also reported to have a specific influence upon the iutestinal canal, curing chronic diarrhoea and dysentery. It deserves a thorough investiga- tion, which I trust some of our practitioners will give it. CINNAMON. Preparation. — "We prepare a tincture from the oil, in the proportion of 5j. to Alcohol 98° 5viij. Dose five to thirty drops. Cinnamon thus prepared exerts a direct influence upon the uterus, causing contraction of its muscular fibre, and arresting hemorrhage. To a limited ex- tent, it exerts an influence on the entire circulatory system, checking hemorrhage from any part. It is the most certain remedy we have for uterine hemorrhage, either during parturition or at the menstrual period. I have used it since I com- menced practice, and have never failed to arrest post-partum hemorrhage with it, though I have had some very severe cases. 110 SPECIFIC MEDICATION. CLEMATIS VIRGINIANA. (Virgin's Bower.) This agent has not been studied, though it de- serves investigation. Prepare a tincture from the recent leaves, in the proportion of 5viij. to Alcohol 76° Oj., using pressure. Dose, gtts. v. to gtts. x. To determine its influence upon the nervous system and upon the secretions. COFFEE, (Java or Rio.) Take of the berries of Coffee, ground (not roasted) gviij., Alcohol, 76° Oj. Make a tincture by perco- lation. Dose gtts. ij. to gtts. x. Coffee is a stimulant to the cerebral nervous sys- tem, and may be employed in many cases where there is atony, with disordered function. Were it not for the general use of coffee as a beverage, it would prove a valuable remedy ; but when persons are habituated to its use, it exerts but little influ- ence. COLLINSONIA CANADENSIS. (Stone Root.) We employ an alcoholic fluid extract of the Col- linsonia, representing the crude article ounce for ounce. As there are a great many imperfect prepa- rations in the market, I would advise that it be procured from one of our own houses in this city. Collinsonia is a specific in ministers' sore throat ; COLCHICUM. Ill administered in the proportion of: Ify Fluid Extract of Collinsonia, Simple Syrup, aa., half teaspoonful to a teaspoonful four times a day. It proves beneficial in other cases of chronic laryn- gitis, in chronic bronchitis, and phthisis, allaying irritation, and checking cough. It also exerts a favorable influence upon the digestive processes, improving the appetite, facilitat- ing digestion, and acting as a general tonic. It passes oft* through the kidneys, and exerts a tonic influence upon the entire extent of the urinary tract. I have thought that its influence was specially ex- erted upon and through the pneumogastric, relieving irritation of, and giving strength to parts supplied from this source. Collinsonia is a specific in the early stages of he- morrhoids, and will sometimes effect a cure in the advanced stages of the disease. In this case it is employed in small doses : Ify Fluid Extract of Col- linsonia, 3j- ; Water, 51 v. ; a teaspoonful four times a day. I have given the therapeutics of Collinsonia thus briefly, that the points named might make the greater impression upon the reader. I regard it as one of the most direct and valuable agents of the Materia Medica, and one that will give satisfaction to whoever employs it. 112 SPECIFIC MEDICATION. COLCHICUM. It is difficult to procure a reliable preparation of Colchicum, and we have beeu obliged to use the English wine of Colchicum. Our manufacturers in this city now prepare a fluid extract, representing ounce for ounce of the crude article. The medium dose is one drop ; we do not desire a cathartic action. Colchicum has long been used as a remedy for rheumatism and gout; and, though probably the best of the old Materia Medica, it failed of giving its best results, because used in poisonous doses. In acute and chronic rheumatism it should be em- ployed in small doses, following or alternated with the sedatives. We only obtain its anti-rheumatic influence when the pulse and temperature are re- duced to nearly a normal standard. It is also beneficial in some cases of intestinal dis- turbance, especially when there are gaseous accu- mulations. Thus in colic from intestinal irritation, it may be employed in the proportion of gtts. xx. to water, 5iv., a teaspoonful every two hours, with prospect of success. It exerts an influence upon the skin, and may occasionally be employed with advantage in chronic disease of the surface. COLQCYNTH. Colocynth has been employed as a cathartic, but for this purpose it is harsh and uncertain, and may well be dispensed with. CYPRIPEDIUM PUBESCENS. 113 I use it wholly as a remedy for dysentery. And for this purpose employ the alcoholic fluid extract, in small doses, usually 5ss. to /Water §iv. A tea- spoonful every hour will give the best results. It will also prove beneficial in some cases of colic, and in diarrhoea attended with tormina and tenes- mus. I am satisfied that a thorough investigation of the remedy in small doses, will develop other im- portant uses. CYPRIPEDIUM PUBESCENS. (Lady's Slipper.) Preparation. — Prepare a tincture from the recent dried root, in the proportion of Sviij. to Alcohol 76° Oj. The dose will range from gtts. ij. to 5j. The Cypripedium is a nerve stimulant, improving the circulation and nutrition of the nerve centers. Hence it proves useful in sleeplessness, nervous irri- tability from atony, in neuralgia, delirium, and other disturbances from the same cause. It is a feeble agent, and too much- must not be expected from it. It is a stimulant, and will only be applicable in nervous atony. Its best use will doubtless be found in children, to soothe irritation of the nervous system. I make the following prescription which is an admirable " Soothing Syrup." Jfc Tinct. of Cypripedium, Comp. Tinct. of Lavender, aa. 3ij. Tinct. of Lobelia, 5j. Simple Syrup, giiiss. M. 10 114 SPECIFIC MEDICATION. DATURA STRAMONIUM. (Jamestown Weed.) The Stramonium is a very active agent, and yet I have not been able to determine any important medicinal use for its internal administration. I doubt whether it exerts any medicinal effect in its common external application ; the good influence, if any, coming from the fomentation in the one case, or the alcohol when used as a tincture. An ointment, prepared by boiling the fresh leaves in mutton tallow, furnishes an excellent local appli- cation for hemorrhoids, and ulceration of mucous surfaces. DELPHINIUM STAPHISAGRIA. (Stavesacre.) Preparation. — A tincture is prepared from the ground seed, (it having been pressed between bibu- lous paper to remove the iixed oil), in the propor- tion of gviij. to Alcohol 98° Oj. The Tincture of Staphisagria has a specific action upon the reproductive organs of both male and female ; but more marked in the first. It quiets ir- ritation of the testes, and strengthens their func- tion ; it lessens irritation of the prostate and vesi- cuhe ; arrests prostatorrhcea, and cures inflamma- tion of these parts. It also exerts a marked influ- ence upon the urethra, quieting irritation and checking mucous, or mnco -purulent discharges; it DIGITALIS PURPUREA. 115 influences the bladder and kidneys, but in less degree. The action of Staphisagria upon the nervous sys- tem is peculiar. It exerts a favorable influence where there is depression of spirits and despondence, in cases of hypochondriasis and hysteria, especially when attended with moroseness, and violent out- bursts of passion. I employ it in the proportion of: Ify Tincture of Staphisagria, 5j ; Water, giv. A teaspoonful every four hours. The seed of the Delphinum Consolida or Larkspur, possesses similar medical properties, but is not so active ; a tincture may be prepared in the same way, and used in the same dose. DIERVILLA CANADENSIS. (Bush Honeysuckle.) Preparation. — A tincture may be prepared from the recent leaves and twigs, gviij. to Alcohol 76° Oj. Dose gtts. x. to 5j- We have no positive knowledge with regard to this agent, though it is credited with active proper- ties. It would be well to test its influence upon the urinary apparatus, and to increase waste and nutri- tion. DIGITALIS PURPUREA. (Foxglove.) Prepare a tincture from the recent dried leaves in the proportion of Sviij. to Alcohol 76° Oj. Dose, 116 SPECIFIC MEDICATION. from a fraction of one drop to five drops. — Ij* Tinc- ture of Digitalis, gtts. x. to xx. ; Water, §iv. A tea- spoonful every one or two hours. Digitalis may be employed for the general pur- poses of a sedative, to lessen the frequency of the pulse, and the temperature, in cases of fever and inflammation. It is somewhat analogous to Aco- nite, and exerts the best influence in atonic condi- tions. For these purposes, however, it must be used in small doses. It is a powerful cardiac tonic when used in small doses, and may be employed iu any case of heart' disease where the organ is enfeebled. It not only gives the necessary stimulation for the present, but it gives a permanent improvement; doubtless through an improved nutrition. It exerts an influence upon the capillary circula- tion, and may be employed with much certainty to arrest asthenic hemorrhages. It also influences the absorption of dropsical deposits, and increases secre- tion from the kidneys, probably in the same way. There is no cumulative effect when Digitalis is used in small doses. DIOSCOREA VILLOSA. (Wild Yam.) An infusion of the recent Dioscorea will un- doubtedly give the best results. A tincture may be prepared from the recent root in the proportion of 5viij. to Alcohol 76° Oj. Dose gtts. x. to 5j. DROSERA ROTUNDIFOLIA. 117 The article that has been sold for Dioscorea by most of our druggists for the past ten years, and from which the Dioscorein has been prepared, is a species of smilax. A very good joke on Dioscorein ! but unpleasant to those who have expected it to relieve pain iu the bowels. True Dioscorea, when recent, is a specific in bilious colic, when given in infusion, or even in tincture. In any case it allays gastro intestinal irri- tation, and favorably influences the vegetative pro- cesses. It is a feeble but certain diaphoretic, and allays irritation of the nervous system. DROSERA ROTUNDIFOLIA. (Sundew.) We employ a tincture of the fresh plant prepared in Germany, using it in the proportion of : ^ Tinc- ture of Drosera, gtts. x. to 5j- ; Water, Si v. A tea- spoonful every three or four hours. I use the Drosera as a specific in the cough at- tending and following measles, especially where there is dryness of the respiratory mucous mem- branes. An experience of ten years with it, in a large number of cases, has given me great confidence in the remedy. We also use it in cases of whooping cough, espe- cially where there is dryness of the air-passages, and much irritation of the nervous system. Whilst it is not a remedy for all cases of whooping cough, it is a true specific in those to which it is 118 SPECIFIC MEDICATION. adapted. I have often seen a serious case of the disease relieved in twenty-four hours, and an entire arrest of the cough in two weeks. We also employ it in cases of chronic cough, with dryness of the air-passages and nervous irritation, with much advantage. It makes little difference whether it arises from bronchial irritation or inflam- mation or phthisis, if associated with irritation of the basilar portions of the brain, and pueumogastric. EPia^A REPENS. (Trailing Arbutus.) This remedy deserves further and careful investi- gation. We wish to determine its influence upon the urinary apparatus, and the intestinal canal. For this purpose a tincture of the fresh leaves may be prepared with dilute alcohol. EPILOBIUM PALUSTRE. For general use the infusion is the preferable form for administration ; but we have a tincture prepared with dilute alcohol, employing pressure. The Epilobium exerts a specific influence upon the intestinal mucous membrane, relieving irritation, and promoting normal function. Thus, it is em- ployed in acute diarrhoea and dysentery, and in colic, with advantage. I have also prescribed it to quiet the irritation and check the diarrhoea in typhoid fever, with marked benefit. It is especially valuable, however, in chronic ERIGERON CANADENSE. 119 diarrhoea and dysentery; sometimes effecting cures where all other means had failed. Thus, I employed it extensively in the treatment of the chronic diar- rhoea during the recent war, and with a success not to be obtained from other remedies. I do not pre- tend to account for its action, bat its curative influ- ence is well established. ERECHTHITES HIERACIFOLIUS. (FlREWEED.) preparation. — A tincture may be prepared from the recent plant, in the usual proportions, using alcohol of 76°. Dose from gtts. x. to 5j. We have here another remedy that requires study. It influences mucous tissue, especially of the bowels and lungs, and this will be the direction of the investigation. ERIGERON CANADENSE. (Canada Fleabane.) We employ the Oil of Erigeron in practice, for the arrest of hemorrhage. For passive hemorrhage it is one of the most valuable remedies we have, and may be relied upon in hemorrhage from any organ or part. For this purpose the dose will be from five to ten drops on sugar, as often as may seem necessary. The Erigeron influences the kidneys in a manner similar to Buchu. It may be employed in diabetes and albuminuria with advantage ; also, in chronic 120 SPECIFIC MEDICATION. inflammation of the kidneys, bladder and urethra. Latterly it has been recommended for gonorrhoea. ERYNGIUM AQUATICUM. (Water Eryngo.) The Eryngium may be employed in infusion, or in the form of a tincture of the recent dried root, oviij. to proof spirit, Oj. Dose, gtts. x. to gtts. xx. The Eryngium exerts a specific influence upon the bladder and urethra, relieving irritation. It is one of the most certain remedies that can be em- ployed in dysuria from irritation, and in spasmodic stricture; continued, it proves curative in these cases. It has been employed for other purposes, and we find it highly recommended. It undoubtedly de- serves a thorough investigation. EUONYMUS ATROPURPUREUS. (Wahoo.) Preparation. — Prepare a tincture from the bark of the recent root, in the proportion of Sviij. to Alco- hol 76° Oj. Dose, gtts. x. to 5j. The Euonymus stimulates the nutritive processes, and in some cases improves digestion. Usually, however, it will need to be combined with a pure bitter, as the hydrastis, to get its full action in this direction. It exerts a marked influence in malarial diseases, and deserves the name of an antiperiodic, though it EUPATORIUM. 121 is much feebler than Quinine. It may, however, be used in these cases with marked advantage, after the fever has been once broken. EUPATORIUM AROMATICUM. (White Snakeroot.) Preparation. — Prepare a tincture from the recent dried root, in the proportion of Syiij. to Alcohol 76° Oj. Dose, gtts. x. to 5j. This variety of the Eupatorium exerts a marked influence upon the brain, relieving irritation and promoting normal action. It is also diaphoretic, and probably influences, to a slight degree, all of the functions governed by the sympathetic. It will repay careful investigation. EUPATORIUM TEUCRIFOLIUM. (Wild Hoarhouxd.) Preparation. — Prepare a tincture from the recent plant, using dilute alcohol. The dose will vary from one drop to one drachm. In small doses it stimulates all the functions con- trolled by the sympathetic nervous system ; im- proving digestion, blood making, and stimulates waste and excretion. It may be combined with a simple bitter tonic, or preparation of iron, or the hypophosphites, for its restorative influence, or with the vegetable alteratives for its other use. In large doses it is a powerful diaphoretic. 11 122 SPECIFIC MEDICATION. EUPATOMUM PURPUKEUM. (Queen or the Meadow.) Preparation. — Prepare a tincture from the recent root, in the proportion of Sviij. to Alcohol 98° Oj. Dose, gtts. x. to l'5ss. Its principal influence is upon the kidneys, and it may be employed whenever an increased volume of urine is desirable. . It has been mostly employed in the treatment of dropsy, with reported success. Its influence upon the urinary organs may doubt- less be made valuable, but it requires further study. EUPATOEIUM PERFOLIATUM. (Boneset.) Preparation. — Prepare a tincture from the recently dried herb in the proportion of oviij. to proof spirit Oj. Dose from gtts. v. to 5j- The Eupatorium increases functional activity of the skin, and to a less extent, secretion from the kidneys. It also influences the circulation, to a slight extent, and does well combined with the sedatives. In quite small doses it stimulates the sympathetic nervous system, and improves all the vegetative functions. It is not an active remedy, and too much must not be expected from it ; yet, in many cases, it may well supplaut costly foreign drugs. FERRUM. 123 EUPHORBIA COROLLATA.— E. IPECACUANHA. (Bowman's Root— Wild Ipecac.) Preparation. — Prepare a tincture of the first from the bark of the root, of the second, from the root, (dried), Sviij. to Alcohol 76° Oj. Dose, gtts. j. to x. These remedies have not been sufficiently studied; yet, possessing active properties, they are likely to prove valuable. The Euphorbia Corollata exercises a direct influence upon the mucous surfaces, reliev- ing irritation, and promoting functional activity. This is noticed more especially in the digestive tract. In quite small doses it improves digestion, both stomachic and intestinal, tends to overcome constipation and irregularity. It may be employed with advantage in some forms of diarrhoea and dysentery, using it in the place of Ipecac. To arrest inflammatory action in the intestinal canal, seems to be its specific use. FERRUM. (Iron.) "We employ two preparations of Iron — Metallic Iron in powder, and the Tincture of Chloride of Iron. The first is Iron by Hydrogen or Quevenne's ; a good article may be known by its iron-gray color and its effervescing with acids, the spurious is black, and effervesces but slightly. The Tincture of Chlo- ride of Iron should be ordered of a reliable manu- facturer. It will be a clear, deep-colored tincture, 121 SPECIFIC MEDICATION. without a trace of yellowness or deposit at the bottom of the bottle. We employ Iron as a restorative. It is a compo- nent part of the red corpuscles, and experience has shown that its administration stimulates the forma- tion of these bodies. In proportion as the red cor- puscles are increased, blood-making becomes more active and nutrition is improved. It thus becomes a very important remedy in cases of anaemia, with impaired nutrition. As a restorative, it is better to administer the necessary quantity of Iron with the food. Experi- ment has demonstrated that at other times it is ap- propriated slowly or not at all. It does not require a very large amount to accomplish the object, for Iron exists in small quantity in the body. The dose of Metallic Iron need never be more than five grains, often not more than one ; whilst of the Tincture, the dose will be from five to twenty drops. In the selection of the preparation I would be guided by the appearance of the mucous membrane. If it is dark-red, use the Tincture of Chloride, if pallid, Metallic Iron. We also employ Iron as a specific against certain zymotic poisons. The reader has probably employed The Tincture of Chloride in erysipelas, and many regard it as a true specific in the disease, rarely making any other prescription. I think we may say, that in all cases of erysipelas presenting the deep-red discoloration of mucous membranes, with the same deep color of the local disease, the Tine- FRASBKA CAROLINENSIS. 125 ture may be prescribed with great confidence. But my experience with the disease has shown me that where the mucous membranes are pallid, the coat- ing of the tongue white and pasty, the Sulphite of Soda is the best remedy. In the*se cases Quevenne's Iron might be tested. Rademacher claimed that Iron was specific to one of his three epidemic constitutions. This was charac- terized by pallor of the skin, moderate heat, with a small, thin or soft, empty pulse. His description, so far as I have seen it in translation, is so meager that we can hardly determine the coudition in which he valued it so highly, even treating all the ca^s of pneumonia in a season with Iron alone. FRASERA CAROLINENSIS. (American Columbo.) Preparation. — Prepare a tincture from the fresh root, in the proportion of fviij. to Alcohol 98° Oj. Dose, gtts. j. to v. This remedy has been but little used, and that little has been of the dried root as a tonic. The recent root possesses quite active properties, and is likely to repay investigation. It is stimulant to the circulation, and will doubtless exert the same influ- ence upon all the vegetative functions. Will some one give it a thorough study and report ? 126 SPECIFIC MEDICATION. FEAXINUS SAMBUCIFOLIA— F. ACUMINATA. (Ash.) Preparation. — Prepare a tincture from the recent bark, in the proportion of Sviij. to Alcohol 76° Oj. Dose from gtts. ij. to f5ss. Both the black &nome desirable property might be developed. 13 146 SPECIFIC MEDICATION. IRIS VERSICOLOR. (Blue Flag) We find the Iris described in our Dispensatory as " among the most valuable of our medicinal plants," " termed the mercury of Eclectic practice," and yet I am safe in saying that there has not been a good article in the market for a dozen years. The dried root of the drug trade possesses no more medicinal property than sawdust, and preparations from it, whether in the form of fluid extract or Irisin, are an imposition. We would prepare a tincture from the fresh root, using Alcohol of 76°. There are two varieties of it, and that should be selected which presents a bluish mottled color on incision. When prepared as above, the Iris is one of our best remedies. It is directly stimulant to waste and excretion, and also influences the lymphatic system. It may, therefore, be employed in all diseases in which there is bad blood, and imperfect nutrition. I regard it as one of our most certain remedies in the treatment of secondary syphilis. It exerts a specific influence in cases of enlarge- ment of the thyroid gland, and has effected cures in very severe cases. Here, as in other cases, we employ it uncombined, giving it internally, and using it as a local application. The dose of the tincture of Iris will vary from five drops to 5j. JUGLANS CTNEREA. 147 JEFFERSONIA DIPHYLLA. (TwiNLEAF.) Preparation. — Prepare a tincture from the recent root, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. xx. The JefYersonia is a stimulant to mucous mem- branes, increasing their circulation, and checking profuse secretion. It may be employed in any case where these influences are desirable, and will give satisfaction. It exerts a feebly stimulant influence upon the skin, sufficient, however, to make it useful in chronic skin diseases. It is also claimed to be diuretic and anti-rheumatic. The remedy requires study, and may develop valuable properties. JUGLANS CINEEEA. (Butternut.) Preparation. — Prepare a tincture from the fresh inner bark, in the proportion of Sviij. to Alcohol 76° Oj. Dose from a fraction of a drop to five drops. In minute doses, the Juglans exerts a marked in- fluence upon the skin, and may be employed in either acute or chronic skin disease. Its influence in this direction requires study. It also allays irritation of mucous membranes, and promotes their normal function. In some cases of intestinal dyspepsia, it will be found to give much better results than the bitter tonics. 148 SPECIFIC MEDICATION. A valuable laxative may be formed by making a watery extract of the Juglans, adding some aromatic to render it pleasant. I have a distinct recollection of the use of Butternut extract in the olden time to cure ague. It was given in large doses, and the catharsis would last for days, its influence being so constant and powerful that the patient would not have inclination or time to shake. In small doses, it leaves the bowels in a soluble condition, and is one of the few cathartics that may be employed to overcome obstinate constipation. JUNIPERUS SABINA. (Savin.) Preparation. — Prepare a tincture from the Savin, in the proportion of oviij. to Alcohol 76° Oj. Dose from gtt. j . to gtts. v. Thus prepared, the Savin is a stimulant. It may be employed in menorrhagia, and in atonic leucor- rhcea, with advantage. It may also be used as a stimulant in vesical catarrh, and in diseases of the urethra. In some cases of amenorrhoea it may be employed as a stimulant, but never in those cases presenting excitement of the circulation. KALMIA LATIFOLIA. (Sheep Laurel.) Preparation. — Prepare a tincture from the recent leaves, in the proportion of oviij. to Alcohol 76° Oj. Dose from a fraction of a drop to five drops. LAURUS SASSAFRAS. 149 This is a favorite remedy of Prof. King, and he describes its use -as follows: "It is an efficient remedy in primary or secondary syphilis, and will likewise be found invaluable in febrile and inflam- matory diseases, and hypertrophy of the heart, allaying all febrile and inflammatory action, and les- sening the action of the heart. In active hemor- rhages, diarrhoea, and dysentery, it has been em- ployed with excellent effect. I have extensively used this agent, and regard it as one of the most efficient agents in syphilis ; and have, likewise, found it very valuable in inflammatory fevers, jaun- dice, and ophthalmia, neuralgia and inflammation." I have employed it in secondary syphilis and atonic chronic inflammations with marked advan- tage, but have not used it for other purposes. Will some of our readers test it in the treatment of fever and inflammation to determine its analogy to the sedatives ? LAURUS SASSAFRAS. (Sassafras.) A very good preparation of the Sassafras for office use, is a tincture of the bark of the root by percolation, using dilute alcohol or whisky. It forms a pleasant vehicle for many remedies, when we desire the gently stimulant and astringent action of the remedy. Tincture of Podophyllum added to it, in the proportion of 5ij. to §iv., in teaspoonful doses four times a day, forms an admirable altera- tive. 150 SPECIFIC MEDICATION. In the treatment of secondary syphilis, especially when manifesting itself in disease of the skin, the infusion will be found preferable. In this case I would direct an infusion of Sassafras with a small portion of Podophyllum, §ss. of the first, grs. x. of the second, to the pint of water, three times a day. It may be associated with the vapor bath, spirit- vapor bath, or sulphur bath in stubborn cases. LARIX AMERICANA. The American Larch deserves study, not in com- bination, as it has been employed, but singly, to de- termine its real medicinal value. For this purpose a tincture may be prepared from the recent bark, in the proportion of oviij. to Alcohol, 30° Oj. It has been employed in combination for a large number of diseases, but its influence upon mucous mem- branes and upon the skin, is probably most definite. LAVANDULA VERA. (Lavender.) Lavender is the child's stimulant, and nothing, so far as I am aware, exercises so kindly an influence upon the digestive apparatus and the nervous sys- tem. A tincture may be formed of Oil of Lavender, gij.; Dilute Alcohol, Oj. But the Compound Spirit will probably answer the needs of most physicians. I would like to test a tincture of the fresh herb, and if any of our readers are so located as to grow it, LEPTANDRA VIRGINICA. 151 and prepare such tincture, we will be obliged if they will report. LEONURUS CARDIACA. (Motherwort.) Prepare a tincture from the fresh root, with dilute Alcohol in the usual proportions. The line of ex- periment will be to determine its influence upon the reproductive organs, and upon the nervous sys- tem. The dose may vary from five drops to 5j. LEPTANDRA VIRGINICA. (Black Root.) For general use prepare a tincture of the Leptan- dra, oviij. to Oj., using Alcohol of 50°. For some purposes the infusion would be preferable, but is so nauseous that most persons object to it. The dose of the tincture as above will vary from gtts. ij. to gtts. xx. The Leptandra exerts a gentle stimulant influence upon the entire intestinal tract, and its associate viscera, and in medicinal doses strengthens func- tional activity. Its action in this direction is so per- sistent that it might be called a gastro-intestinal tonic. There are some functions not well under- stood, as or the liver and spleen, and it would not much improve our knowledge to say that it acted upon these. But it exerts a marked influence in those diseases in which there is enfeebled portal circulation, and tendency to stasis of blood. Thus 152 SPECIFIC MEDICATION. in'some cases of typhoid fever occurring in mala- rial localities the Leptandra has proven a very valu- able medicine. We do not believe there is any remedy that acts upon the liver, according to the old idea of medicine. It has been conclusively proven that preparations of Mercury do not, and that Podophyllin does not ; and it is probable that we will have to give up the idea of cholagogues entirely. There is no doubt in my mind, however, that Leptandra does influence the function of the liver ; not always to increase secretion of bile, but rather to bring the organ back to normal functional activity, whatever may have been the deviation. Associated with the milder bitter tonics the Lep- tandra improves the digestive function, and stimu- lates normal excretory action from the bowels. This latter influence sometimes makes it a valuable adjunct to those remedies called alterative. It has been employed in the treatment of inter- mittent fever with excellent results. Dr. Rolph writes, that "for many years my father's family employed it exclusively, and though living in a malarial region they were entirely exempt from ague. They used a tincture of the recent root, tak- ing it before each meal." Quite a number of my acquaintances employ it after the chill has been broken with Quinine, and claim that its influence in preventing a recurrence is more decided than any other remedy. LIQUIDAMBAR STYRACIFLUA. 153 LEPTANDRIN. The best Leptandrin of the market is a dried alco- holic extract, the strongest is obtained by adding a portion of Podophyllum before tincturing. The resin is nearly worthless. The dried extract proves a very good remedy in many cases, and may be used for the same purposes as named for the tincture or infusion. LIATRIS SPICATA. (Button Snakeroot.) Preparation. — Prepare a tincture from the recent root, 5viij. to Alcohol 76° Oj. Dose from gtts. v. to 5ss. The Liatris is gently tonic, and stimulates secre- tion from all the emunctories. Hence it has been added to various alterative combinations, and with some practitioners is very highly esteemed. It acts more directly upon the urinary apparatus, and prob- ably upon the reproductive apparatus of both male and female. LIQUIDAMBAR STYRACIFLUA. (Sweet Gum.) Some years since we had sweet gum, the exudation from this tree, recommended for the cure of asthma, and a number of cases from the South were given as proof. But experiments in the Northern States were not favorable. I judge, however, from some reports of Southern physicians, that the recent bark 154 SPECIFIC MEDICATION. contains valuable medicinal properties, as does the fresh exudation. For experiment I would suggest the preparation of a tincture from the fresh bark, using Alcohol of 76°. Its influence is probably most marked on mucous membranes, and probably it influences innervation from the pneumogastric and from the spinal cord. LIKIODENDRON TULIPIFE-KA. (Yellow Poplar.) Preparation. — Prepare a tincture from the fresh root bark of the Yellow Poplar, using dilute Alcohol. Dose from gtts. v. to 5j- The great abundance and wide distribution of these trees, and the ease with which it may be ob- tained and prepared, and the really valuable char- acter of the remedy, should bring it into general use. It is stimulant and tonic to the digestive ap- paratus, improving digestion and blood making. It also exerts an influence upon the nervous system, strengthening innervation and relieving those symp- toms called nervous. LOBELIA INFLATA. (Lobelia.) Preparation. — Prepare a tincture from the ground seed, Sviij. to Alcohol 98° Oj. Dose, from the frac- tion of a drop to ten drops. The common use of Lobelia as an emetic is so well known that little need be said about it. In LOBELIA INFLATA. 155 the form of trie Compound Powder of Lobelia, or the Acetous Emetic Tincture of the Dispensatory, it gives us our most valued emetic when properly used. To obtain the curative effects of a lobelia emetic, the remedy should be given in small quanti- tities frequently repeated, as it can be absorbed from the stomach, so that emesis when it does occur shall be from the general influence of the remedy iu the blood, and not from its local irritant influence upon the stomach. Many physicians fail to obtain the benefit they have reason to expect because of its improper administration ; it is not absorbed, but simply irritates the stomach. Lobelia as prepared above is one of the most powerful vital stimulants in the Materia Medica. It strengthens the circulation, improves innervation,' and by its influence upon the sympathetic nervous system gives increased activity of all the vegetative functions. These influences come from minute doses, one drop or less. I usually prescribe it in this proportion : ly Tincture of Lobelia, gtts. x. to xx. ; Water, §iv. A teaspoonful every one or two hours. In some cases where there is necessity for a speedy action, as in cases of angina pectoris or neu- ralgia of the heart, I give one or two full doses of twenty drops. This preparation of Lobelia is specific in difficult labor from rigid os, vagina, or perineum. It also stimulates the contractile function of the uterus, and thus strengthens the pains. This use of Lobelia 156 SPECIFIC MEDICATION. will be greatly prized when known. In tardy or difficult labor add 5j- of the tincture to §iv. of water, and give a teaspoonful every fifteen minutes until slight nausea is produced, then in smaller quantities. In rigid os or perineum, I frequently employ it in the same way, and with excellent results, but in other cases give it in larger doses until nausea is in- duced. Lobelia is a sedative, occupying a place between Veratrum and Aconite. I would be glad if ea&h reader would put the tincture of the seed in his pocket case and employ it in fevers and inflamma- tions in the same doses in which he uses Veratrum. I think it will prove very valuable, especially where there is necessity for stimulation. LYCOPUS VIRGINICUS. (Bugle Weed.) Preparation. — Prepare a tincture from the fresh plant gathered in July and August at the time of flowering, using Sviij. to Alcohol 76° Oj. The tincture of Lycopus prepared as above, will be found a very valuable remedy, and will take place with Veratrum and Aconite. It is a very cer- tain sedative, where increased frequency of pulse is dependent upon want of power. For this purpose we employ it in all forms of chronic disease with frequent pulse, and in the advanced stages of acute disease where there is great debility. iSro remedy is more certain in its action in these cases ; and we 157 will find that as the pulse is reduced in frequency, it is increased in strength, and there is a more regular and uniform circulation of blood. The remedy evidently acts upon the sympathetic system of nerves, and we not only have an improve- ment in the circulation, but every vegetative func- tion feels its influence. Thus it improves the appe- tite and blood-making, nutrition and secretion. It has been employed more extensively in the treatment of hemoptysis than in any other disease. In these cases its action is slow, but very certain, and its influence seems to come from its sedative action — in this it resembles Digitalis. Employed in phthisis, we find it relieving the cough, checking- night sweats and diarrhoea, lessening the frequency of the pulse, improving the appetite and giving better digestion. We observe the same influence from the protracted use of Veratrum in these cases, evidencing the relationship between the remedies. Those who live where the Bugle weed can be gathered, should not neglect the opportunity of procuring the fresh plant and preparing a tincture for the coming year. I am satisfied that it will well repay the trouble. MAGNESIA, SULPHITE OF. Sulphite of Magnesia was one of the anti-zymotic remedies recommended by Prof. Polli. We find in all that class of acute diseases which develop typhoid 158 SPECIFIC MEDICATION. symptoms as they progress, a need for remedies which control the septic process in the blood. Most physicians will have employed Sulphite of Soda in these cases, and have found marked advan- tage from its use, yet in other cases, presenting somewhat similar general symptoms it has done no good, and in some has done harm. We say that Sulphite of Soda is indicated where the tongue is broad, pallid, and covered with a pasty white coat. In these cases it will rarely disappoint the practitioner. But we have need of the same antiseptic remedies in cases in which the tongue is deep-red or dusky, whether covered with a brown fur, or presenting the smooth glistening appearance noticed in some of the more severe cases of typhoid fever, or typhoid disease. Whenever the tongue is thus dark-red, we can not give the Salt of Soda, for there is present a prominent indication for the use of an acid. We may use Sulphurous Acid as the antiseptic, but fre- quently it is not well borne by the stomach. In these cases the Sulphite of Magnesia will be found an admirable remedy. We may say that it may always be administered when the tongue is dark-red, and shows a dark fur, and there is need for a remedy to antagonize the septic process in the blood. It is given in doses of grs. x. to grs. xxx., repeated every three hours. MARRUBIUM VULGARE. 159 MAGNOLIA. The Magnolia Glauca and Accuminata possess tonic and stomachic properties, which may prove useful in medicine. Will some of our Southern readers prepare a tincture from the recent bark, and test it thoroughly. It may not prove better than a dozen similar articles, and yet supply a very good medicine to those who live where it is abundant. MARRUBIUM VULGARE. (HOARHOTJND.) Preparation. — Prepare a tincture from the fresh plant when in flower, using 5viij. to Alcohol 76° Oj. Dose from gtts. j. to gtts. x. The Hoarhound exerts a marked influence upon the respiratory apparatus. It is stimulant to all mucous surfaces, but especially to the laryngeal and bronchial, and it may be employed for this purpose. But it evidently has an action beyond this, and in- fluences the function of respiration. Any one who has employed it will have seen this very marked in some cases. Let us have it thoroughly tried, and it may be another instance of a very valuable rem- edy, in a common article. 160 SPECIFIC MEDICATION. MARUTA COTULA. (Mayweed.) In testing these indigenous remedies, will some one prepare a tincture from the fresh May weed and give it a thorough trial ? The direction of the in- vestigation will be shown by reference to the Dis- pensatory or Materia Medica. MENISPERMUM CANADENSE. (Yellow Parilla.) The Yellow Parilla has been considerably em- ployed for the indefinite purpose of an alterative. We have the testimony of the Dispensatory that : " In small doses, no obvious effects are produced on the general system." It may be worth while, how- ever, to examine it further, and it will offer a good subject of study to some of our readers. For experiment, prepare a tincture from the fresh root, §viij. to Alcohol 76° Oj. Use it in doses of from gtts. v. to 5j- MENTHA VIRIDIS. (Spearmint.) Preparation. — Prepare a tincture from the fresh herb, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to 5j. Mentha Viridis is not only a stimulant, but is one of the most kindly of the aromatics, and is rarely rejected by the stomach. As a stimulant, it will MITCHELLA REPENS. 161 furnish a cheap and pleasant vehicle for many med- icines. But it is more than this. I regard it as one of the most certain of the vegetable diuretics, and em- ploy it frequently for this purpose. In suppression of urine in children, a teaspoonful of the tincture is added to two ounces of water, sweetened, and given freely. So certain is its action in childhood, that I rarely think of giving anything else, except in cases where there is great irritation of the ner- vous system^ and then Gelseminum is added to it in the usual doses. MITCHELLA REPENS. (Partridgeberry.) Preparation. — Prepare a tincture from the fresh plant, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to 5ss. The Mitchella exerts a direct influence upon the reproductive apparatus of the female, giving tone and improving functional activity. It has been ex- tensively used as a uterine tonic, to promote men- struation, to remove false pains and unpleasant sen- sations in the latter months of pregnancy, and has been thought to be a good preparative to labor, ren- dering the birth of the child easier, and less liable to accidents. Many have failed to obtain these influences from the use of the common preparation " Compound Syrup of Partridgeberry," because it was prepared 14 162 SPECIFIC MEDICATION. from old materials. If made from the green plant, as named above, we think it will give satisfaction. ELATEMUM. The common use of Elaterium, as a hydragogue cathartic is well known. I desire to call attention again to its direct action as described by Prof. King in the Eclectic Medical Journal, January, 1870, page 16. He claims that it is specific for " Chronic In- flammation of the Neck of the Bladder." Since the article was published I have received reports from two physicians as to its efficiency. He pre- pared the tincture by adding one drachm of Elate- rium to one pint of Alcohol. Dose, half a fluid drachm three times a day until it acted upon the bowels, then six or eight drops. MANATROPA UNIFLORA. (Ice Plant.) Will some of our subscribers prepare a tincture from the Ice-plant, and test it in the cases named in the Dispensatory. We especially want to know its influence upon the nervous system, and its action as a sedative. It is claimed to be remedial in con- vulsions, epilepsy, chorea, etc. » MYRICA CERIFERA. 163 MYRICA CERIFERA. (Bayberry.) Preparation. — We prepare a tincture from the re- cent bark, in the proportion of oviij. to Alcohol 76° Oj. As the Bayberry deteriorates unless carefully kept, it would be better to test a tincture of the fresh bark of the root. The dose will range from gtt. j. to 5ss. I do not know that anything can be added to what is known of this agent. It has been exten- sively employed as a general stimulant, and as a special stimulant to mucous membranes, and with excellent results. Thomson recommended it in all cases where there was increased secretion from mucous membranes, whether it was catarrh or sore throat, bronchitis, disease of stomach or intestinal canal, or leucorrhcea. It is in these cases especially that it will be found of advantage. I have employed it in chronic gas- tritis in- small doses, associated with minute doses of Lobelia, with good success. The same combina- tion will prove very valuable in typhoid fever, in typhoid dysentery, and in diarrhoea with increased mucous secretion. The tincture prepared as above, will furnish a much better form for dispensing, as well as a more reliable remedy than much of the powder sold, and when once used, will become a prominent agent in the Office and the pocket case. 164 SPECIFIC MEDICATION. MOMORDICA BALSAMINA. (Balsam Apple.) The Balsam Apple is an annual climbing plant, grown in our gardens for its fruit, which is em- ployed in domestic practice as a vulnerary, and an application to old sores, chapped hands, piles, etc. It is commonly prepared for use with alcohol or whisky. It evidently possesses medicinal proper- ties, and I have seen good effects from its local use. It is claimed to be poisonous when taken inter- nally, yet I have known it taken with safety in doses of ten to thirty drops. Cures of dropsy are reported from its use. The limited use I have known made of it internally, was to relieve muscu- cular pains, lame back, and stiffness of joints ; in some cases it seemed to do good. As the agent is very common, and easily cultivated, it would be well to prepare a tincture from the fresh fruit Sviij. to Alcohol 76° Oj., and test it thoroughly, both as a local remedy, and used internally. Of such a preparation the dose would be quite small, say com- mencing Avith one drop. NABALUS ALBUS. (Lion's Foot). Preparation. — Prepare a tincture from the fresh plant, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. XX. This remedy has been but little employed. It was claimed to be specific to the poison of the rat- NICOTIANA TABACUM. 165 tlesnake, and to have been used Avith much success. It influences the nervous system directly, and ex- periment may develop a valuable use for it. It is not in the market, and we will therefore have to depend upon those who can procure it green, to de- termine its properties. NEPETA CATARIA. (Catnip.) Preparation. — Prepare a tincture from the fresh herb when in blossom, Sviij. to Alcohol 76° Oj. Catnip is a feeble remedy, and yet is as good as many in general use. Employed in the form named it will give satisfaction and well repay its prepara- tion. It is a mild diaphoretic, but associated with the hot-foot bath, it will be found to place the skin in a soft moist condition, and relieve nervous irrita- tion. It is especially to be recommended as a car- minative for children. A teaspoonful added to four tablespoonfuls of hot water and sweetened, may be given freely, and is better than a tea of the dried herb. NICOTIANA TABACUM. Dr. Unziker, of this city, recommends the prepa- ration of a tincture from the green plant, and its use as a sedative and in the treatment of diseases of the respiratory apparatus of children. We value the local use of tobacco as a fomenta- tion in cases of strangulated hernia, in some acute 166 SPECIFIC MEDICATION. local inflammations, and in pseudo-membranous croup when the danger is imminent. It will also prove the best application to wounds and injuries where there are symptoms of tetanus. In tetanus the alkaloid, Nicotine, has been em- ployed with marked success, and it is probably our most certain remedy. It is given in doses of half to one drop, or if not tolerated by the stomach, it may be used by hypodermic injection. If the alka- loid can not be procured, an infusion may be used by mouth, by injection, or if not retained in suffi- cient quantity in these ways, it may be given by hypodermic injection. NYMPHJEA ODORATA. (White Pond Lily.) Preparation. — Prepare a tincture from the fresh root of the White Pond Lily, in the proportion of gviij. to Alcohol 50° Oj. Dose from gtts. x. to 5j- My use of this remedy has been but limited, though from the reports of others, I deem it to pos- sess decided medicinal properties. The general term alterative will express the kind of action that may be obtained from it. It exerts a special influ- ence upon mucous tissues, and has been employed with advantage in diseases of the bronchise, the gas- trointestinal mucous surfaces, the bladder and the urethra. This will suggest the line of experiment, and we hope the remedy will be thoroughly tested and reported. ORIGANUM VULGARE. 167 OLEUM MORRHUJ& (Cod Liver Oil.) We employ a bland and slightly odorous Cod- liver Oil in practice; probably Caswell & Mack's will give most satisfaction. There is no doubt but benefit follows its use in appropriate cases, and sometimes the advantage is much greater than from the use of medicines. The principal indication for its use, is when an exalted temperature is maintained at the expense of the tissues. Cod-oil in such cases saves the tissues, and the burning of histogenetic food. I employ it in cases of tuberculosis, scrofula, and in many forms of chronic disease, when the above- indications exist. Especial attention is. called to its use in local disease, with cacoplastic or aplastic de- posits. As the increased temperature is associated with increased frequency of pulse, we commonly associate it with Yeratrum Viride. As a general rule the stomachic bitters are not advantageous at the same time. Many physicians fail to obtain advantage from the use of Cod-oil because they give tonics in excess at the same time. ORIGANUM VULGARE. (Origanum.) Preparation. — Prepare a tincture from the fresh herb, using Sviij. to Alcohol 76° Oj. Dose, gtts. x. to5j. 168 SPECIFIC MEDICATION. This agent is a stimulant diaphoretic, and influ- ences the reproductive organs of the female. It has been used in the treatment of colds, and in sup- pressed menstruation from cold. OROBANCHE VIRGINIANA. (Beech Drops.) Beech drops contain a large proportion of tannic and gallic acids, and may be used for the general purposes of an astringent. I do not know that there is any advantage in taking a crude material that is scarce and high priced, when we can obtain its med- ical action from that which is common and cheap. PiEONIA OFFICINALIS. Prepafhtion. — Prepare a tincture from the fresh root of the garden peony, in the proportion of sviij. to Alcohol 76° Oj. Dose from drops gtts. v. to 5ss. This remedy has been but little used, yet the evi- dence is pretty conclusive that it possesses a marked influence upon the nervous system. It has been em- ployed as an antispasmodic, and to relieve irritation of the nerve centers. Will some of our friends prepare a tincture in the summer and test it ? PANAX QUINQUEFOLIUM. (Ginseng.) Preparation. — Prepare a tincture from the fresh or recent root, in the proportion of Sviij. to Alcohol 50° Oj. Dose from gtts. v. to gtts. xx. PAPAVER SOMNIFERUM. 169 "We have laughed at the Chinese for their use of Ginseng, which we have deemed inert, but I am pretty well satisfied that in thi$ as in some other things, they have the advantage of us. A limited use of the article has given me a very favorable opinion of its influence. Its first use, and a very important one, is in the treatment of nervous dyspepsia. I have obtained more benefit from it in my own person, than from any other remedy, and I have employed it with others with equal advautage. It exerts a decidedly beneficial influence in exhaustion of the brain from oyer work, and it is probable that its influence is as much in this direction as upon the stomach. It is one of those remedies, however, that pro- duces no marked improvement at first, and must be continued for weeks to obtain its good effects. PAPAVEft SOMNIFEEUM. Before describing the action of Opium, I want to draw the attention of my readers to the importance of having it good, and of not using Morphia as a substitute. Never buy Opium in powder, and in selecting the gum, take that which when broken gives the characteristic odor. Lastly, prepare your own tincture of Opium. Opium in medicinal doses is a cerebral stimulant, and we will find this its most important use. From this stimulation comes sleep and rest to the nervous system. 15 170 SPECIFIC MEDICATION. Ill less degree it is a stimulant to the spinal-cord, and increases functional activity of all parts supplied from it. • Opium or its salts may be administered for the relief of pain, to produce sleep, or as a general stimulant to the vegetative processes, when the fol- lowing conditions are present : A soft, open pulse, or where there is not the element of hardness and smallness ; a soft (not dry) skin; a moist tongue; pallid face ; and eyes dull, immobile or dilated pupils. It is contra-indicated, where there is a dry, contracted skin ; small hard pulse ; dry tongue ; flushed face ; bright eye, with contracted pupils. ^ There is no remedy that has been so much or so badly used as this. It is highly prized by the pro- fession, and yet every physician can recall cases where its administration has proven injurious rather than beneficial. It has gained this extensive use because of the marked relief it gives from pain, and even though it fails so frequently, the successes are estimated, not the failures. I believe the reader, by cartfully studying the above indications and contra-indications, will be en- abled to use the remedy so as to obtain its full pal- liative and curative action; not having the. un- pleasantness of failure to accomplish the desired ob- ject, or injury to the patient, to regret. Hypodermic Use op Morphia. — In this connection y^we may consider the advantages to be obtained from the hypodermic use of Morphia. It has been ^ extensivelv employed for the relief of pain, and PAPAVER SOMNIFERUM. 171 many physicians would hardly practice medicine if forced to give up their hypodermic syringes. The advantages to be obtained from this use of Morphia has not been over-estimated. But every one who has employed it, will recollect cases of failure, sometimes of injury, which were very mor- tifying. Why the failure ? The indications for the hypodermic use of Mor- phia are the same as those just given for Opium, and where there is present the contra-indications, the use will not give the expected results, and may prove injurious. Fortunately, in the majority of cases of neuralgia, there is a soft, open pulse, the cool pallid skin, and the evidence of an enfeebled cerebro-spinal circulation. In such cases, the hypo- dermic use of Morphia gives present relief, and from its topical stimulation, may effect a radical cure. We never employ the hypodermic injection of Morphia where there is a hard, small pulse, dryness and constriction of skin, dry tongue, flushed face, bright eyes and contracted pupils. He who uses it in such cases, will very certainly be disappointed in its action. In many cases of fever and inflamma- tion, though the patient suffers pain, and the ordi- nary influence of Morphia in this way would be very desirable, we withhold it. 172 SPECIFIC MEDICATION. PEROXIDE OF HYDROGEN. Water receives au additional equivalent of oxygen, when it is presented to it in a nascent state. This combining with the hydrogen forms a deutoxide (H02.) It was first brought to the notice of the profes- sion by Dr. B. W. Bichardson, of London, in 1860, and since has been used to a limited extent. He employed it in acute and chronic rheumatism, and in chronic inflammation with aplastic deposits. It improved digestion and nutrition, increased waste, oxidation and excretion. PHOSPHORUS. Preparation. — We prepare a tincture of Phospho- rus, by taking gij. to Alcohol 98° Oj. The Phosphorus is divided under water, which being removed the Alcohol is poured on ; it is allowed to stand for ten days, when it is ready for use. We use an excess of the Phosphorus, because in the commercial article there is but a small por- tion which can be acted upon by Alcohol. When of full strength, the tincture will contain about four grains to the ounce. We prepare it for use by add- ing one or two drachms of the tincture to four ounces of water, of which the dose will be one tea- spoonful. We employ this preparation of Phosphorus prin- cipally for its action upon the urinary and repro- PHOSPHATE OF SODA. 173 ductive apparatus. It is especially useful to relieve vesical and prostatic irritation, especially when arising from or associated with sexual excess. We also use it as a nerve stimulant. In some cases its influence will be quite marked, relieving irritation and improving nutrition. THE HYPOPHOSPHITES. The Hypophosphites, when well prepared, gives us Phosphorus in the best form as a restorative. There is great difficulty, however, in obtaining re- liable preparations, and many have been disap- pointed on this account. I now use the Compound Syrup of the Hypophos- phites (Gordon's), and it has given good satisfaction. It is especially useful when it is desirable to improve the nutrition of the nerve centers, though it exerts a favorable influence over the entire process of nutrition. I usually prescribe it in doses of a tea- spoonful three times a day after meals. Its action is slow, like food, and time must be given to obtain its full benefit. PHOSPHATE OF SODA. We employ a pure article of Phosphate of Soda, and demand that it be finely powdered; probably Powers & Weightman's will give the most satisfac- tion. The Phosphate of Soda has two uses — as a re- storative, and for its influence upon the intestinal 174 SPECIFIC MEDICATION. tract. As a restorative I employ it extensively with children, in those cases where there is impaired nu- trition, with pallidity of tongue and mucous mem- branes. In these cases it will he found to exert a markedly beneficial influence. It is generally ad- ministered in milk in doses of one to three grains, four times a day. We occasionally find a case in the adult where it will prove beneficial. These are uniformly marked by the pallid mucous membranes, and inaction of the bowels. The dose will vary from five to fifteen grains. Its second use is as a laxative for children. We find cases of constipation that will yield to no reme- dies, the child suffers from indigestion, and occa- sionally from colic. In these cases Phosphate of Soda in doses of from three to iive grains, three times a day, will give permanent relief. Phosphate of Soda is also an excellent laxative for the adult, especially in cases of habitual consti- pation, with hardened feces. In this case twenty to thirty grains in a large glass of water, is taken on going to bed at night PHYTOLACCA DECANDEA. (Poke.) Preparation. — We prepare a tincture from the fresh root, §viij. to Alcohol 76° Oj. Dose gtts. ij. to oss. This is one of those remedies that loses its medi- cal properties by drying, and the crude article fur- PIPER NIGRUM. 175 nished from drug stores is wholly worthless, as are the preparations from it. The tincture of ike fresh root is one of my favor- ite remedies. It exerts a direct influence upon the processes of waste and nutrition, and therefore pos- sesses those properties called alterative in a high degree. I have used it in secondaiy syphilis, in chronic skin disease, and in scrofula, with excellent results. It has a direct influence upon the mammary glands, and will generally arrest inflammation if given in the early stage. I also employ it in cases of sore nipples, "both internally and locally, with good results. It has been considerably employed in diphtheria, and many believe it will be found a specific to the sore throat. In this disease it is given internally, and employed as a local application. It will be found a very valuable remedy, and as it is so common, I would advise every one to prepare them a tincture in the fall and test it in practice. PIPER NIGRUM. (Black Pepper.) We make a tincture of Black Pepper in the pro- portion of Sviij. to Alcohol 76° Oj. The Pepper should be finely ground and packed in the percola- tor, moistened with Alcohol and allowed to stand twenty-four hours, then run the remainder of the Alcohol through it. Dose, gtts. ij. to 5j. 176 SPECIFIC MEDICATION. Black Pepper is a remedy I value very highly. As a gastric stimulant it certainly has no superior, and for this purpose we use it in congestive chills, in cholera morbus, and other cases of a similar character. In atonic dyspepsia it maybe associated with Hydrastis or other stomachic bitter, or some- times with Nux Vomica or Strychnia. I have used it associated with Tincture of Macrotys in atonic amenorrhcea with advantage, and sometimes the same combination will be found beneficial in dys- menorrhea a. It may be used with excellent results in the treat- ment of intermittents, preparing the way for Quinia and associated with it. In these cases it is used in full doses. PIX LIQUIDA. (Tar.) We prepare a glycerole of tar for local use in the following way : Heat a pound of glycerine and of tar in separate vessels ; whilst heating, rub up an ounce of starch in a mortar with a portion of the glycerine, and stir it in until thoroughly mixed ; when hot pour the two together, boil for a moment, then stir until cool. Glycerole of tar prepared in this way is a specific for many forms of pruritus. In pruritus-ani it is so certain in its action, that I prescribe it with an almost positive certainty that it will not only give present relief, but will effect a radical cure. In eczema with pruritus, it has proven an admirable PODOPHYLLUM. 177 remedy, and has effected cures in protracted and very stubborn cases. The indication for its use is itching. Tar has been used internally, with reported good effects. To test it in chronic bronchial disease, and for the relief of cough, I would suggest one part of tar to nine parts of glycerine, combined with heat. PLANTAGO CORD ATA. (Water Plantain.) Preparation. — Prepare a tincture from the fresh root, Sviij. to Alcohol 76° Oj. Dose from gtts. x. to 5ss. This remedy has been but little used, yet from what we know of it, we think it deserves careful investigation. It exerts a direct influence upon the nervous system, allaying irritation and giving better innervation. It was employed in the cholera of 1832 with marked success, and Prof. Jones thinks it likely to prove one of the most certain remedies we have in that disease. Let some of our physi- cians prepare the remedy, and report. PODOPHYLLUM. (May Apple.) For common use, prepare a tincture from the root in the proportion of sviij. to Alcohol 76° Oj. Dose gtt. j. to 5ss. 178 SPECIFIC MEDICATION. I am satisfied that a trial of a tincture of Podo- phyllum will satisfy any one that it is preferable to Podophyllin in general practice. It makes no dif- ference whether it is#to be used as a stimulant to the digestive tract, as an alterative, for its general cathartic effect, or as an emeto-cathartic. For its stimulant influence and to improve diges- tion, I frequently use it in combination with the stomachic bitters, or lSTux Vomica, Quinia, and Iron ; necessarily the dose is small. As an altera- tive, a remedy to increase waste, it may be combined with other agents that act in the same direction, with the bitter tonics and restoratives, or many times with Yeratrum. A common prescription of mine is : 1^ Tincture of Yeratrum, 5ss. ; Tincture of Podophyllum, Tincture of JSTux Vomica, aa 5j. ; Water, §iv. A teaspoonful every four hours. In place of water, the vehicle may be simple syrup or glycerine, a tincture of Mentha Viridis or of Amyg- dalus. The case in hand will suggest the best vehicle. I am well satisfied that in small doses, associated with the bitter tonics and restoratives and good food, it is decidedly the best remedy we have in the treatment of old syphilitic lesions. Its action may be greatly aided sometimes by the use of the vapor- bath, or by sulphur and iodine baths. For common use in malarial fevers, where the tongue is uniformly coated yellow, I would suggest its combination with Yeratrum and Aconite, as in the following : ^ Tincture of Yeratrum, gtts. xx. ; PODOPHYLLIN. 179 Tincture of Aconite, gtts. x. ; Tincture of Podo- phyllum, 5ss. to 5j.; Water, 5iv. A teaspoonful every hour. For the ordinary routine of medicine, as a cathar- tic, combine it with neutralizing cordial, as Jfy Tinc- ture of Podophyllum, 5ij. to §ss. ; Compound Syrup of Rhubarb, §jss. A teaspoonful every two or three hours. The addition of a small portion of Tinctures of Lobelia or Ipecac will render its action more efficient and kindly. As an emeto-cathartic give it with a ginger-tea, or other stimulant taken freely. PODOPHYLLIN. To obtain the direct action of Podophyllin, we prepare it for use by thorough trituration with sugar of milk or white sugar. I prefer the trituration one part of Podophyllin to one hundred of sugar. The specific use of Podophyllin in this form is to arrest increased mucous secretion from the small intestine and give it power to perform its function. It will cure acute or chronic diarrhoea with mucous discharges, and in some cases of cholera infantum it " acts like a charm/'' No one who has used the trituration of Podophyllin in these cases would be willing to dispense with it, and many will find it of advantage in other cases. 180 SPECIFIC MEDICATION. POLEMONIUM REPTANS (Jacob's Ladder.) This remedy has been but little used, yet it might repay study. If some of our friends will prepare a tincture from the fresh root and test it, we would be glad to hear the report. POLYGALA SENEGA. (Senega.) Preparation. — Prepare a tincture from the recent dried root, Sviij. to Alcohol 50° Oj. Dose, gtts. ij. to gtts. xx. The stimulant influence of Senega upon the throat and bronchial mucous membrane is well known, and is probably its most important use. For this purpose I prefer to use it in the form of tincture to that of syrup so commonly employed. In chronic bronchitis with profuse secretion, it may be combined with small doses of Ipecac and Vera- trum. Its influence upon the kidneys and reproductive organs needs to be studied, and I have no doubt some important uses will be found for it. I have employed it in squamous disease of the skin, and like its action very much ; it is one of a very few remedies that influence these diseases. POLYTRICHUM JUNIPERUM. 181 POLYGONUM PUNCTATUM. (Water Pepper.) Preparation. — Prepare a tincture from the fresh herb, in the proportion of Sviij. to Alcohol 76° Oj, Dose gtts. ij. to 5ss. I regard the tincture of Water-Pepper as one of our most certain stimulant diaphoretics. It is also one of the best emmeoagogues, especially when the arrest is from cold. It influences the urinary and reproductive organs, but its action in these direc- tions needs to be studied. POLYPODIUM VULGARE. (Polypody.) This remedy is now but little used, yet will prob- ably repay study. For experiment, a tincture should be prepared from the fresh root with dilute alcohol, in the usual proportion POLYTRICHUM JUNIPERUM. (Hair-Cap Moss.) The hair-cap moss has been especially employed as a diuretic, and so long as it could be readily pro- cured without admixture, gave good satisfaction. I do not know that it has any direct inilueuce, other than to increase the secretion of water in the urine — a hydragogue diuretic ; but it might be well to study its action more closely. 182 SPECIFIC MEDICATION. POPULUS TREMULOIDES. (Poplar.) Preparation. — Prepare a tincture from the fresh bark of the white poplar, iu the proportion of Sviij. to Alcohol 76° Oj. Dose 5ss. to 5j. This remedy is so common and may be so easily prepared, that it should come into more general use as a tonic and stomachic. It improves the appetite and strengthens digestion, exerting its influence more especially upon the upper intestine. It influ- ences the urinary organs, but its action in this direc- tion needs to be studied. PRINOS VERTICILLATUS. (Black Alder.) Preparation. — Prepare a tincture from the recent bark of the Black Alder, in the proportion of 5viij. to Alcohol 50° Oj. Dose from gtts. v. to 5ss. This remedy is a stimulant to the digestive and blood-making organs, and may be advantageously employed for the general purposes of a tonic. But beyond this, it influences the vegetative processes, probably through the sympathetic system of nerves, strengthening the circulation, aiding nutrition, and the removal of waste. We have used it but little, yet the testimony in its favor is such, that we strongly recommend its trial. PTERIS TRIFOLIATA. 183 PRUNUS VIRGINIANA. (Wild Cherry.) The tincture of Prunus should be prepared from the fresh inner bark, in the proportion of oviij. to Alcohol 50° Oj. Dose from gtts. v. to 5ss. In addition to its tonic influence, which it pos- sesses in common with many of our indigenous bit- ters, it has other valuable medicinal properties. It allays irritation of mucous membrane, both of the gastro-intestinal canal, the respiratory tract, and urinary apparatus. This will probably prove its most important use. The influence upon the circu- lation and upon secretion is not decided, but in atonic states will sometimes be found very desirable. In some of these cases I have combined it with the Tincture of Nux Vomica or Solution of Strychnia, with excellent results. The remedy is so common, and so easily prepared, that it should find a place in every office, and I have no doubt that as it is employed, other uses than those named will be developed. PTELEA TRIFOLIATA. (Wafer Ash). » Preparation. — Prepare a tincture from the bark of the root, Sviij. to Alcohol 76° Oj. Dose gtts. x. to 5ss. Ptelea is an excellent tonic, hardly surpassed in its general uses by any agent of our Materia Medi- ca, if we except Hydrastis. It may be employed 184 SPECIFIC MEDICATION. in all atonic states of the stomach and upper intes- tinal canal, when it is desirable to increase the ap- petite and digestion. It is claimed to exert an in- fluence upon the respiratory apparatus, but we have never noticed any action other than as a tonic. PTERIS ATROPURPUREA. (Rock Brake.) A tincture should be prepared from the entire plant fresh, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to gtts. x. This remedy has been but little used except in domestic practice. It exerts a marked influence upon the excretory apparatus, controlling diar- rhoea, dysentery, night sweats, hemorrhages, etc. This may depend to some extent upon its tannic acid, but there is an influence beyond this. Will some of our practitioners prepare a tincture and test it, and report ? PETROLEUM. There are two varieties — the heavy and the light coal-oils, which differ as much in their medicinal properties as they do in use — probably the heavy should alone be used. A very pure and heavy oil, known as Mecca Oil from the well that yields it, is recommended. It is a dark, bland oil — not unpleasant to the taste, and is furnished by the gallon from our druggists at $2.00. PROPYLAMIN. 185 It has been employed with advantage in chronic bronchitis and laryngitis, and phthisis, with bron- chial irritation. Some contend that for bronchial disease it is unsurpassed. It has also been em- ployed in scrofula, chronic disease of the urinary apparatus, and in chronic skin diseases. It would be well to test it thoroughly in these cases, and also for its influence upon the nervous system. The dose will vary from one drop to a teaspoonful. PROPYLAMIN. The Propylamin of commerce is obtained from herring pickle, and is in the form of a colorless trans- parent liquid ; the muriate is in the form of powder and is about two-thirds of its strength. We pre- pare it for use by adding twenty-four drops, or thir- ty-six grains of the Muriate of Propylamin to six ounces of mint water, the dose of which will be from a tea to a tablespoonful. Investigation has determined that Propylamin is the same as the Secalin derived from Ergot. My use of the remedy clearly proved the analogy be- tween the Propylamin and Ergot in its poisonous effects. The remedy was introduced by Dr. Owenarius of St. Petersburgh, Russia, as a specific for rheuma- tism, and a large number of cases were reported in which it had proven curative in a short time. This was in 1856, and it was tested in this country as well as in Europe, but without very satisfactory results. 16 186 SPECIEIC MEDICATION. I employed it in quite a number of cases of rheu- matism, and at first thought very favorably of its action, but developing marked typhoid disease in some cases I became alarmed and dropped it. I am confident it possesses a marked influence upon the animal economy, but unless used with care, it is as likely to be for evil as good. I developed a typical typhoid fever with it, that ran a course of ■£lyq weeks, with intestinal irritation, rose-colored spots and typhomania. It was evidently due to the medicine, as when its administration was com- menced it was a case of simple inflammatory rheu- matism about the fifth day, and there was no such thing as typhoid fever that year. In employing the Propylamin in the treatment of rheumatism, I think it necessary to first bring the circulation fully under the influence of the seda- tives, and then establish secretion — now the remedy may be used with safety. In doses much smaller than named, I feel confi- dent the Propylamin will be found a stimulant to the entire vegetative functions. It strengthens the circulation, improves nutrition, and stimulates waste and secretion. In these directions it deserves thorough investigation. The proportions I would recommend would be gtts. v. to gtts. x. to mint water oiv., a teaspoonful every three or four hours. Or better, Tfy Muriate of Propylamin, grs. x. ; Sugar of Milk, grs. 1000 ; triturate thoroughly; dose one to Hve grains. PULMONAEIA OFFICINALIS. 187 PTEROSPORA ANDROMEDA. (Crawley.) Preparation, — Prepare a tincture from the fresh plant and root, Sviij. to Alcohol 76° Oj. Dose from gtts. j. to v. The Crawley is a very scarce article, and in the market commands a high price. When the practi- tioner can obtain it and prepare it himself, he will find it one of the most valuable of the Materia Medica. It possesses decided sedative properties, and may be employed for this purpose, but its prin- cipal use is to establish waste and secretion. Fol- lowing or associated with Veratrum or Aconite, there is no remedy that will more quickly and cer- tainly establish secretion from skin and kidneys. It is probable that other uses will be developed by experiment. PULMONARIA OFFICINALIS. (Lungwort.) Preparation, — Prepare a tincture from the fresh leaves, Sviij. to Alcohol 50° Oj. Dose, from ten drops to 5ss. The Lungwort has a popular reputation as a remedy in diseases of the chest. It would be well to test it thoroughly and determine its medicinal action in this direction. 188 SPECIFIC MEDICATION. PULSATILLA NIGRICANS. (Pulsatilla.) We employ the German tincture prepared from the fresh herb according to the Homoeopathic phar- macy. That prepared from the imported dried herb will not give good satisfaction. We usually prescribe it in this proportion : ^ Tincture of Pul- satilla, 5j. to 5\j. ; Water, §iv. A teaspoonful every four hours. The principal use of Pulsatilla is to relieve certain cerebral symptoms with difficulty relieved by other remedies. In some diseases of women, in sperma- torrhoea and prostatorrhoea, in heart disease, and some other chronic affections, we find certain head symptoms playing an important part, and giving a good deal of trouble. The patient is nervous, rest- less, has an active imagination for disease, a fear of impending danger, etc. These symptoms are very unpleasant, and not unfrequently prevent the cura- tive action of remedies. Pulsatilla reaches them and gives prompt and certain relief. I would not treat some cases of spermatorrhoea without I could employ this remedy. For with the unnatural excitement of the mind, no remedy would exert a curative influence. So in some cases of heart disease, the head symptoms are the most prominent and unpleasant features. Relieve the unpleasant mental sensations and dread of danger, and we have removed a permanent cause of excite- ment. PYRETHRUM PARTHENIUM. 189 Though Pulsatilla is the remedy for nervousness, it must not be given with any expectation of benefit when the excitement depends upon irritation and determination of blood. In this case it will either exert no influence or it will be unfavorable. The Pulsatilla exerts a marked influence upon the reproductive organs of both male and female. I regard it as decidedly the best emmenagogue, when the suppression is not the result of or attended by irritation and determination of blood ; where there is simple suppression from atony or nervous shock, it may be used with confidence. In male or female it lessens sexual excitement. It does not diminish sexual power, but rather strengthens it by lessening morbid excitement. There are other uses for the remedy, but those I have named are prominent ones, and readily recog- nized. I value the remedy very highly, and am satisfied from an experience of ten years in its use that I do not overestimate it. PYRETHRUM PARTHENIUM. (Feverfew.) Preparation. — Prepare a tincture from the fresh plant, Sviij. to Alcohol 50° Oj. Dose from gtts. v. to 5ss. The Feverfew has the reputation of being an ad- mirable tonic, at the same time being one of the most pleasant of its class. It influences the entire intestinal tract, improves the appetite and digestion, and stimulates secretion. It also exerts an influence 190 SPECIFIC MEDICATION. upon the skin and kidneys. This is one of the little used medicines that deserves careful study, and as it is cultivated in our gardeus it is within the reach of all. PYROLA ROTUNDIFOLIA. (False Wintergreen.) Preparation. — Prepare a tincture from the fresh plant, §viij. to Alcohol 50° Oj. Dose from gtts. v. to 5ss. This also is likely to prove a valuable remedy and deserves to be studied. It has marked tonic prop- erties, and exerts an influence upon the urinary organs, relieving irritation. It is claimed to exert an influence upon the nervous system, and to have been successfully employed in convulsions and epilepsy. PYRUS MALUS. (Apple Tree.) Preparation. — Prepare a tincture from the fresh root-bark of the apple-tree, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to 5ss. Though so common and easily prepared, this remedy has been but little studied. It possesses tonic and antiperiodic properties, and may be em- ployed in a great many cases instead of more costly remedies. The only use I have made of it was in intermittent fevers, and whilst it was not a substi- tute for Quinia, it evidently exerted a good influ- QUINIA SULPHAS. 191 ence upon the disease, especially in preventing a recurrence of the paroxysms. QUERCUS RUBRA. (Red Oak.) The Eed Oak is not only astringent from its tan- nic acid, but it possesses other properties that will render it useful in some cases. Among them is its tonic influence, and its action upon skin and kid- neys. I have used it in chronic eczema associated with Rumex, both as a local and internal remedy, with marked advantage. A combination of Quer- cus Rubra, Rumex and Alnus is my favorite remedy in obstinate cases of scrofula where there are old ulcers, feeble tissues and cicatrices. In these cases I use it as a local application and as an internal remedy. I have employed it principally in infusion and de- coction, but for experiment would recommend the preparation of a tincture, Sviij. of the fresh inner bark to Alcohol 76° Oj. Dose from gtts. v. to 5ss. QUINIA SULPHAS. (Quinine.) There is no occasion to give a lengthy description of the specific action of Quinine, as every one of my readers is thoroughly conversant with it. But it may be of use to some, to state the conditions neces- sary to its kindly and medicinal action. 192 SPECIFIC MEDICATION. Probably there is no remedy in the Materia Medica that gives so many failures as this, and I think we may be safe in assuming that it is given ten times where its specific action is obtained once. Every one wiU recollect cases in which it did not break up periodic disease, many more cases in which its influence was but temporary, a large number in which it produced unpleasant cerebral symptoms, and some in which a Quinia disease was developed, which was much worse than the original malady. Why is this ? Is it the fault of the remedy, the fault of the patient, or the fault of the practitioner? O, the doctor answers, it is from idiosyncrasy I So we believe, but wTe locate the idiosyncrasy in the doctor's head, and not in the patient. I have taught for years, that if we are to expect the kindly and curative actiou of Quinia, the stomach must be in condition to receive and absorb it, and the system in condition for its action. If we have a proper condition in these respects, we wTill hear nothing of roaring in the ears, vertigo, etc., but its action will be most kindly. The rule is very simple — Given, a soft and open pulse, a moist skin, moist and cleaning tongue, and Quinia will act kindly, antidote the malarial poison, or in small doses im- prove innervation. Always get this condition before prescribing the remedy, aud you will never be dis- appointed in its action. As an antiperiodic I believe in prescribing single doses. Put the stomach in proper condition, regu- late the circulation, establish secretion, and then QUINIA SULPHAS. 193 give one full dose of the remedy, (10 to 15 grs.) The best form of the remedy is in solution with one or two ounces of water, using a sufficient quantity of sulphuric acid. This is not only the most certain method of admin- istration, but I think it will be found the most pleasant. It is hardly necessary to impress upon the reader the necessity of determining the periodic element in disease. Whilst we may not know what it is, or how Quinine antidotes it, we know that its removal cures, or at least paves the way to a cure. But Quinine is not specific to all agues. We see it given day after day, week after week, in many cases, without any advantage. But on the contrary, it excites the nervous and vascular systems, and at last produces a chronic erythism of them, that is correctly named "the Quinine disease." From this, recovery is far more difficult than from the mala- rial affection. Is it possible then, to determine the cases in which Quinine will prove specific, and the cases in which it will fail ? I think it is. It antidotes the mala- rial poison only when kindly received and absorbed, and when the system is in such condition that it can be readily excreted. Given, the condition of pulse, skin and tongue; that we have already named, and its action is as certain as could be de- sired. In some cases, the general treatment directed to obtaining normal activity of the various functions, 17 194 SPECIFIC MEDICATION. is the most successful. In some cases Nux Vomica or Strychnia is preferable. In others minute doses of Arsenic antagonizes the malarial poison. Whilst in some rare cases, I have treated the disease most successfully with Aconite and Belladonna. As a stimulant to the cerebro-spinal centers, its use is very important. In many forms of disease, especially in the advanced stages, we find an im- paired innervation, preventing functional activity, or its restoration and continuance by the use of remedies. It is essential to success that innerva- tion be increased, not temporarily by the use of stimulants, but somewhat permanently. This we accomplish by the administration of small doses of Quinine (grs. J to grs. ij). Even here, we find it necessary to observe the rules for its administration already noticed — the patient must be prepared for its use. » It favorably influences the nutrition of the nerve centres, and hence is employed in the treatment of chronic disease with enfeebled innervation, with marked advantage. There are two classes of chronic disease in which it is useful — the one in which there is a malarial influence, with obscure periodicity, and the other the enfeebled innervation, as named above. Its general tonic and stomachic influence, (when obtained) is most certainly from this action upon the nervous system — the influence extending to the sympathetic ganglia, as well as to the cerebro-spinal centers. In some cases this action is very impor- POTASSII FERROCYANURETUM. 195 tant, improving digestion and blood-making, and nutrition, as well as waste and excretion — aiding " the renewal of life." POTASSII FERROCYANURETUM. (Prussiate op Potash.) The Prussiate of Potash was omitted in its proper place by mistake. It is a remedy I value highly, and though little used it is certain to become a favorite. We find it in market in the form of prismatic crystals of a clear lemon-yellow color, inodorous, possessed of a sweetish-bitter saline taste. If the salt is dirty, dark-colored, or parti-colored, it should be rejected. We prepare it for use by adding gss. to Water, §iv. Dose, one teaspoonful every three hours. In chronic disease where there is marked irrita- bility of the nervous system, with frequency of pulse, we will find it an excellent remedy. It les- sens irritation of the nervous system, and acts as a special sedative to the circulation. In chronic dis- ease of the reproductive organs in women, with hysterical manifestations, it exerts a direct and marked influence — so in hypochondriacal affections in the male. It exerts a decided influence upon mucous mem- branes. When they are pallid, lax, and give in- creased secretion, the Prussiate of Potash may be used with advantage. It makes little difference, whether of nose, throat, bronchial tubes, intestinal 196 SPECIFIC MEDICATION. mucous membrane, or chronic vaginitis with leu- corrhcea, the influence is the same. This will suggest to the practitioner the cases in which it may be tested : where there is excitation, but impaired nutrition of the nerve centres, and where there is feebleness of mucous membranes with in- creased secretion of mucus. RANUNCULUS BULBOSUS. (Crowfoot.) Preparation. — Prepare a tincture from the fresh root in the proportion of Sviij. to Alcohol 76° Oj. Dose, the fraction of a drop, very largely diluted with water. The remedy is exceedingly acrid, and must be used with care. Prof. King reports the cure of nursing sore mouth by its internal administration in small doses in in- fusion. It has also been employed as a stimulant to the vegetative processes, with reported good re- sults. It should be thoroughly tested, and we will be obliged to any one of our readers for a report. Prescribe it in about the following proportion : 1^ Tincture of Ranunculus, gtts. x. ; Water, oiv. Dose, a teaspoonful. RHAMNUS CATHARTICUS. (Buckthorn.) Two preparations of this agent may be used. Prepare a tincture from the fresh bark in the pro- portion of Sviij. to Alcohol 50° Oj. Dose, gtts. vj RHEUM PALMATUM. 197 to gtts. xxx. Prepare a tincture from the berries, in the proportion of Sviij. to Alcohol 76° Oj. Dose, from the fraction of a drop to two to five drops, largely diluted with water. Buckthorn berries have been employed as a cathartic, but their activity, attended with nausea, dryness of the throat, thirst and tormina, made their use limited. The tincture of the berries in small doses may be tested for its influence on the digestive apparatus, in diseases of the nose, throat, and respiratory organs, and as a stimulant to the vegetative processes. It is claimed that a preparation from the bark gives one of the most efficient alteratives of the Materia Medica. Dr. William Goltry claimed that a tea made of the bark or berries would cure cancer and scrofulous diseases generally. Dr. William S. Knight writes, " I have been using the Khamnus Catharticus in all forms of scrofulous disease for the last two years (1866) with good effect. I make an infusion from the bark and let the patient drink as much as he well can during the day, so as not to act too much upon the bowels." RHEUM PALMATUM. (Rhubarb.) Preparation. — Prepare a tincture from the best Russian, Turkey, or India Rhubarb, in the propor- tion of sviij. to Alcohol 50° Oj. Dose, from the fraction of a drop to ten drops. It is not worth while to speak of the common use 198 SPECIFIC MEDICATION. of Rhubarb, as there is no remedy better known and more used. But it will be noticed that we have recommended a wholly different preparation, and we propose to dispense it in small doses for its direct action. In the proportion of Ify Tincture of Rhubarb, 5j-, Water, §iv., a teaspoonful every half hour or hour, it will be found one of our best remedies to control irritation of the stomach, and arrest vomiting. In children it is especially useful, where there is ner- vous irritability, manifested by restlessness, screams, and convulsive contraction of muscles. In the same doses, less frequently repeated, it will prove an excellent tonic, strengthening the functions of both stomach and intestines, giving improved digestion. In indigestion, with some diarrhoea, of a papescent character, it will be found a good remedy. In some cases it will prove our best remedy in the treatment of obstinate constipation. The cases are those in which there is an unnatural sensation of constriction in stomach and bowels, and contraction of the abdominal muscles. I prescribe it in these cases in doses of ten drops in a large glass of water, on rising in the morning. In the severer cases it is associated with thorough fatty innunction over the abdomen, and friction. I employ it as a restorative, where there is special need of increased nutrition of nerve tissue. It is thus associated with the preparations of Phospho- rus, and with Cod Liver Oil. RHUS GLABRUM. 199 RHODODENDRON CHRYSANTHUM. (Rhododendron.) A tincture is prepared from the fresh leaves col- lected in September ; that we employ is imported from Germany. Two native species — the R. Maxi- mum and R. Punctatum possess similar properties, but much milder, and should be tested. The influence of the Rhododendron on the circu- lation is very marked. It undoubtedly acts like Veratrum and Aconite, stimulating the circulatory apparatus through the sympathetic, and diminish- ing the frequency of the pulse by increasing the power of the heart, and removing capillary obstruc- tion. Acting in this way, it has been employed with advantage in rheumatism, gout, syphilis, and some acute diseases. It is claimed to exert an influence upon the reproductive apparatus, being used in or- chitis, in suppression of gonorrhoea, and in hydro- cele. It has been but little employed in this coun- try, but our native specimens deserve a thorough examination. RHUS GLABRUM. (Sumach.) Preparation. — Prepare a tincture from the fresh root bark, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to gtts. xx. The Sumach as thus prepared exerts a direct in- fluence upon the processes of waste and repair — al- terative. It has not been much used, and we caii 200 SPECIFIC MEDICATION. not tell whether it will prove better than others of this class ; still it deserves a thorough trial. It is claimed to be antidotal to the action of mercury, especially in chronic mercurial disease, and has been employed in the treatment of secondary syphilis, after mercurialization, with advantage. RHUS TOXICODENDRON. (Poison Oak.) Prepare a tincture from the recent leaves, Sviij. to Alcohol 76° Oj. Added to water in the propor- tion of gtts. v. to gtts. x. to §iv., the dose is a teaspoonful. The R. Radicans, R. Venenata, and R. Pumilum may be prepared in the same manner, and deserve a thorough investigation. The Rhus is likely to prove one of our most valuable medicines, and will be highly prized when its use is learned. It is antidotal to such animal poisons (zymotic) as determine to the skin, in ery- sipelas or erysipeloid disease, or in low grades of inflammation of cellular tissue, or in low grades of inflammation of mucous membranes. A frequent, small pulse, redness of mucous membranes, brown sordes, bright superficial redness of skin, tympani- tis, acrid discharges from bowels or bladder, are in- dications for its use. So also is inflammatory action, presenting tumid, bright reddened tissues, deep seated or superficial burning pain, inflammation giving an ichorous discharge, in which the tissues seem to melt away without sloughing. Old ulcers, that present reddened, glistening edges, scrofulous RHUS TOXICODENDRON. 201 or syphilitic disease, with tumid-red, glistening swellings. I have preferred to thus point out distinctly the indications for the use of the Khus, without refer- ence to the disease, according to our present nomen- clature. It will he seen to point to erysipelas, typhoid fever and typhoid disease in general, and the entire list of zymotic diseases. Our Homoeopathic friends give the following in- dications for its use : " Affections of the ligaments, tendons and syno- vial membranes ; tensions, drawing and tearing in the limbs, worse during rest, and in the cold season, or at night, in bed, frequently attended with numb- ness of the affected part after moving it; creeping pains ; sensation in inner organs as if something would be torn loose ; lameness and paralysis, also hemiplegia ; vesicular erysipelas ; rhagades ; pus- tules which break and discharge a fluid ; hang- nails ; red, shining swelling ; violent and spasmodic yawning ; evening fever, with diarrhoea ; sweat dur- ing the pains, frequently with violent trembling ; illusions of the fancy, and delirium ; pain as if the brain would be torn ; painful creeping in the head ; swelling of the head ; phagedenic scald-head ; small, soft tumors on the hairy scalp ; swelling and in- flammation of the parotid glands; acne rosacea around the mouth and chin ; nightly discharge of yellowish, or bloody saliva ; ulcerative pain in the pit of the stomach as if something would be torn oft*, especially when stooping or making a false 202 SPECIFIC MEDICATION. step ; the small of the back feels as if bruised, es- pecially when lying still on it." BOBINIA PSEUIX)-ACACIA. (Black Locust.) Preparation. — Prepare a tincture from the fresh inner bark of the Black Locust, Bviij. to Alcohol 76° Oj. Dose from gtts. j. to gtts. x. This remedy has been but little used, yet its ac- tivity is such that we may reasonably expect that experiment will develop some valuable medicinal use. It acts on the stomach and bowels in large doses, and exerts an influence upon the nervous sys- tem. Will some of our readers test it and report ? RUMEX ACETOSELLA. (Sheep Sorrel) Preparation. — Prepare a tincture from the fresh sorrel, gviij. to Alcohol 50° Oj. Dose, from gtts. x. +o 5ss. It is employed locally in the treatment of cancer, the following formula being employed : " Cancer Balsam. — Take the common Sheep Sorrel when in bloom, bruise well in a mortar, and add a small quantity of water ; then press the weed so as to obtain all the juice, strain it and place in the sunshine in a pewter dish, and let it evaporate to the consistence of honey. It is then ready for use, and should be put up in sealed boxes or closely stopped bottles, in order to prevent evaporation." A tincture of the Sorrel has a very decided action RUMEX CRISPUS. 203 in those cases where there is a tendency to degene- ration of tissue. It makes no difference whether it is called syphilis, scrofula, or cancer, the indication for use is the replacement of tissue with lower or- ganizations. To what extent it opposes the pro- cess of degeneration we are unable to say, the use has been so limited, but it deserves a thorough in- vestigation. It influences the secretion of urine and urinary apparatus, but its medicinal action in this respect has yet to be determined. Its use in the treatment of cancer has been quite extensive, and if we can believe the reports given, it has proven fully as successful as any other reme- dy. A full description of this method of treatment will be found in the Eclectic Journal for May, 1870, jpage 142. RUMEX CRISPUS. (Yellow Dock.) Preparation. — Prepare a tincture from the fresh root, 5viij. to Alcohol 76° Oj. Dose gtts. x. to 5j. We employ Eumex in cases of bad blood with dis- ease of the skin ; in these cases it is certainly one of the most valuable alteratives we have. In these cases we not only use it internally, but as a local application. In scrofulous disease, with deposit in glands and cellular tissue, with tendency to break down and feeble repair, I think the Eumex un- equaled ; here also, we use it internally and locally. Dr. Hale reports cases of dyspepsia, with sensa- 204 SPECIFIC MEDICATION. tious of fullness and pressure in pit of stomach, pain in the chest, etc., cured by Rumex. Dr. Dunham employed it in catarrhal affections of the larynx, trachea and bronchia with advantage. I have used it in chronic sore throat with free secre- tion, and in broncorrhoea with good results. The general action of the remedy is to increase waste and improve nutrition. KUTA GHAVEOLENS. (Rue.) Preparation.~-Pre*pa.ve a tincture from the fresh plant, Sviij. to Alcohol 76° Oj. Dose gtts. j. to gtts. x., largely diluted with water. Though little used, this remedy will be found to possess valuable medicinal properties. It exerts a,, direct influence upon the nervous system, relieving irritation and pain, and in small doses, continued, improving nutrition of the nerve centers. It acts upon the urinary and reproductive apparatus, and has been employed with advantage as a stimulant to them. In large doses, it is capable of exciting menorrhagia, inflammation, and miscarriage. The Homoeopaths claim that it is a remedy " in eructa- tions of hysteric females ; prolapsus of the rectum, at every alvine evacuation ; frequent urging to uri- nate, with scanty emission, also of green urine, or with renewed ineffectual urging after micturition ; gravel ; miscarriage ; sterility ; corrosive leucor- rhcea after suppression of the menses." SALIX NIGRA. 205 SABBATIA ANNULARIS. (American Centaury.) Preparation. — Prepare a tincture from the fresh herb Sviij. to Alcohol 76° Oj. Dose, gtts. j. to gtts. xx. The Sabbatia has had a considerable reputation as a prophylactic against periodic diseases, and in their treatment — it would be well to thoroughly investigate this action. As a bitter tonic, it may be successfully employed in atonic states of the intes- tinal canal with increased mucous secretion. Prob- ably it will prove useful in all diseases of mucous membranes, where there is profuse secretion. It has been but little used of late, but it deserves study. SALIX NIGRA. (Black Willow). Preparation.- — Prepare a tincture from the recent bark, sviij. to Alcohol 50° Oj. Dose from gtts. v. to5j. Whilst this, as well as other varieties of the wil- low, possess feeble tonic and antiperiodic proper- ties, there are so many better remedies of this class that it would be well to dispense with its use alto- gether, had it no other action. But there is a class of cases in which the Salix is a very decided anti- periodic, and if these can be distinguished, the rem- edy will be valuable. I believe it is in those in which there is increased secretion from mucous membranes, and especially where there is the septic 206 SPECIFIC MEDICATION. tendenc}^ marked by fetid discharges, foul tongue, etc. In typhoid disease it may be employed both as a tonic and antiseptic, using the smaller dose named. The remedy is easily prepared, and may well replace some inferior articles that have hitherto been employed. SALVIA OFFICINALIS. (Sage.) Preparation. — Prepare a tincture from the fresh plant when in flower oviij. to Alcohol 76° Oj. Pose from gtts. j. to gtts. xx. The Sage exerts a specific tonic influence on the skin, and to a less extent upon the kidneys and mucous membranes. It is not an active remedy, and hence too much must not be expected from it. We employ it where the skin is soft and relaxed, with an enfeebled circulation and cold extremities. In the treatment of colliquative perspiration it an- swers an excellent purpose, if the condition above is maintained. If, however, the night sweat is pre- ceded with hectic fever, and a dry, harsh skin, it will be useless. It will prove a good remedy in increased secre- tion of urine of low specific gravity ; in such cases it may be associated with Belladonna. It may also be associated with the bitter tonics in all cases in which there is atony and increased secretion from mucous membranes. SAMBUCUS CANADENSIS. 207 SAMBUCUS CANADENSIS. (Elder.) Preparation. — Prepare a tincture from the fresh inner bark of the Elder, Sviij, to Alcohol 50° Oj. Dose gtts. ij. to gtts. x. The Elder is a stimulant to all the excretory or- gans increasing secretion. It may be employed for the general purposes of an alterative— increasing- waste, in syphilis, scrofula, and other diseases at- tended by deposits or depravation of tissues. It is especially useful in these cases where there is an oedematous condition, or fullness of tissue from an increased amount of water. We meet a case of chronic disease occasionally, in which the tissues are full and flabby, evidently from too much water ; in these Sambucus is a good remedy. It may be em- ployed in dropsy, though its action is not so decided as the Apocynum. As a local application the Sambucus is specific to those eruptions that arise on full tissues (as above), and are attended with abundant serous discharge. Thus in some forms of eczema, especially eczema infantilis or milk scall, and in the above form of the disease, it will alone effect a cure. We also employ it in indolent ulcers, with soft oedematous borders, and serous secretion, and in mucous patches with free secretion. An ointment is prepared by sim- mering the inner bark in fresh butter (old style), or a grycerole may be made, with the addition of the usual quantity of starch. 208 SPECIFIC MEDICATION. SANGUINAKLA CANADENSIS. (Blood Root.) Preparation. — Prepare a tincture from the recent dried root, Sviij, to Alcohol 76° Oj. Dose from a fraction of a drop to live drops. Nitrate of San- guinarina is a valuable preparation, and may be dis- pensed in syrup, in the proportion of grs. ij. to §j. Dose, gtts. x. to 5j. In full doses we employ the Sanguinaria as a stimulant to mucous membranes. This use is valu- able in bronchitis with increased secretion, and in atonic conditions of stomach and bowels with in- creased secretion of mucus. In minute doses we employ it in cases of cough with dryness of the throat and air passages, feeling of constriction in the chest, difficult and asthmatic breathing, with sensation of pressure. In the same doses it is a stimulant to the vegetative system of nerves, and under its use there is an improvement in the circu- lation, in nutrition, and secretion. As a remedy in diseases of the respiratory tract, I prefer the Nitrate of Sanguinarina to the tincture. SANICULA MARILANDICA. (Sanicle.) Preparation. — Prepare a tincture from the recent root in the proportion of oviij. to Alcohol 76° Oj. Dose from gtts. ij. to gtts. xx. The Sanicula has had considerable reputation as a domestic remedy, and like most of them it has SARRACENIA PURPUREA. 209 been employed for very different purposes. It evi- dently exerts a direct influence upon the nervous system, relieving irritation, and this probably ex- tends to the sympathetic. It would be well to give it a trial in those cases in which there is enfeebled function with nervous irritability. SARRACENIA PURPUREA. (SARRACENIA.) Preparation. — Prepare a tincture from the fresh root, in the proportion of oviij. to Alcohol 76° Oj. Dose from gtts. j. to gtts xx. The experiments of Dr. Porcher, of South Caro- lina, showed that it exerted a marked influence on the sympathetic. From a large dose there was congestion of the head, with irregularity of the heart's action, lasting several days. Following this first effect, the general vigor of the digestive appa- ratus was increased, and the appetite was unusually active. It is claimed that it has been successfully employed in chlorosis, and other diseases of a simi- lar character. It was introduced to the notice of the profession by Dr. W. Morris, of Halifax, in 1861, as an anti- dote to the virus of smallpox. He made the fol- lowing statements in a letter to the American Medi- cal Times: " Sir — You have by this time, in all probability, heard something of an extraordinary discovery for the. cure of smallpox, by the use of * Sarracenia Purpurea,' or Indian cup, a native plant of Nova 18 210 SPECIFIC MEDICATION. Scotia. I would beg of you, however, to give full publicity to the astonishing fact, that this same humble bog-plant of Nova Scotia is the remedy for smallpox, in all its forms, in twelve hours after the patient has taken the medicine. It is also as curious as it is wonderful that, however alarming and numerous the eruptions, or confluent and frightful they may be, the peculiar action of the medicine is such that very seldom is a scar left to tell the story of the disease. I will not enter upon a physiologi- cal analysis now ; it will be sufficient for my pur- pose to state, that it cures the disease as no other medicine does — not by stimulating functional re- agency, but by actual contact with the virus in the blood, rendering it inert and harmless ; and this I gather from the fact that if either the vaccine or variolous matter be washed with the infusion of the Sarracenia, they are deprived of their conta- gious properties. The medicine, at the same time, is so mild to the taste, that it may be mixed largely with tea or coffee, as I have done, and given to connoisseurs in these beverages to drink, without their being aware of the admixture. Strange, how- ever, to say, it is scarcely two years since science and the medical world were utterly ignorant of this great boon of Providence ; and it would be dishon- orable in me not to acknowledge that had it not been for the discretion of Mr. John Thomas Lane, of Lanespark, County Tipperary, Ireland, late of Her Majesty's Imperial Customs of Nova Scotia, to whom the Mec-Mac Indians had given the plant, SARRACENIA PURPUREA. 211 the world would not now be in possession of the secret. Kb medical man before me had ever put this medicine upon trial, but in 1861, when the whole Province of Kbva Scotia was in a panic, and patients were dying at the rate of twelve and a half per cent., from May to August, Mr. Lane, in the month of May, placed the ' Sarracenia ' in my hands to decide upon its merits ; and, after my trials then and since, I have been convinced of its astonishing efficacy. The only functional influence it seems to have, is in promoting the flow of urine, which soon becomes limpid and abundant, and this is owing perhaps to the defecated poison or changed virus of the disease exclusively escaping through that channel. The ' Sarracenia/ I have reason to believe a powerful antidote for all contagious dis- eases, lepra, measles, varicella, plague, contagious typhus, and even syphilis, also a remedy in jaun- dice. 1 am strongly inclined to think it will one day play an important part in all these." This report was confirmed by Dr. Herbert Miles, of the British Army, and Captain Hardy of the Royal Artillery. The evidence in its favor from physicians and residents of Sbva Scotia would seem to be complete, that the Sarracenia has a direct prophylactic influence, and a direct and prompt curative action when the disease is devel- oped. The remedy, however, has been thoroughly tried by a number of physicians in the United States, and by physicians in private practice, and in the hospi- 212 SPECIFIC MEDICATION. tals in England, with the report that if not entirely inert, it has no such antidotal power as has been ascribed to it. The evidence against it is just as positive as that in its favor. What conclusion can we come to then? The only way we can reconcile these opposing state- ments is, that the same agent was not employed in both cases. In Nova Scotia, where the plant is abundant, we may suppose it was used fresh; in the United States and in England, it was dried and so old that it had lost its medical properties. I am confirmed in this opinion by my experience. Wish- ing to try this remedy, I obtained three samples, and neither of these possessed in the least degree the physical properties attributed to Sarracenia. When fresh, it is bitter and astringent, leaving a somewhat pungent impression on the fauces. The specimens I obtained had no taste. In order to give the remedy a fair trial, let us have it prepared from the fresh root, obtained at the proper season. If an antidote to smallpox, its value can not be over-estimated ; if it only exerts the influence over the sympathetic first named, it will prove a valuable remedy. SCUTELLARIA LATERIFLORA. (Skullcap.) Preparation. — Prepare a tincture from the fresh herb, gathered whilst in flower, Sviij. to Alcohol 76° Oj. Dose, from gtt. j. to gtts. xx. SECALE CORNUTUM. 213 We have here another remedy that loses its medical properties by drying, until by age they are entirely dissipated. I have seen specimens furnished physicians by the drug trade that were wholly worthless — no wonder they were disappointed in its action. The Scutellaria exerts a direct influence upon the cerebro-spinal centers, controlling irritation. It is possible that it may also exert a tonic influence, favoring nutrition. It has been employed with suc- cess in chorea, convulsions, epilepsy, mania, etc., and especially in hysteria, monomania, and that un- defined condition that we call " nervousness." I value the remedy highly, but only recommend it when prepared from the fresh plant as above. SECALE CORNUTUM. (Ergot.) Preparation. — Prepare a tincture from recent Ergot Sviij. to Alcohol 50° Oj. Dose from the frac- tion of a drop to 5j. (Ergot loses its properties with age, and it is essential, if we wish its specific action, that the tincture be prepared from the grains of the present season.) The Ergot may be taken as the type of a specific medicine. Its action on the uterus, when fresh and good is so certain and decided, that no one can fail to see that at least one remedy acts directly. It is true, that there have been many failures in obtain- ing this action, but this can be attributed to worth- less medicine ; a large amount of that furnished 214 SPECIFIC MEDICATION. physicians from drug-houses being inert from age. Ergot may be employed in two ways, to facilitate labor. In quite small doses, say — 1^ Tincture of Ergot, 5j. ; Water, 5ij. ; a teaspoonful every half hour or hour, it exerts a stimulant influence, strengthening uterine contractions, and aiding dila- tation of the os. It is especially useful in those cases in which there is a feeble circulation, with pufhness of face, and oedema of the feet — among the worst cases we are called to treat. Associated with small doses of Lobelia, it is an admirable rem- edy in rigidity, the os being thick and doughy. Its common use in large doses, in the second stage of labor, is so well known that it need not be de- scribed. We employ Ergot in small doses, in the latter months of gestation, when there are false pains, with weight and pressure in the pelvis, fullness of labia with uneasiness, oedema, and especially if there is dullness and hebetude, with tendency to coma. In these cases no remedy will give greater satisfaction. Ergot is a spinal stimulant, and influences the vegetative system of nerves. In some respects its action is similar to Belladonna, especially upon the circulation. ISTot unfrequently, we find it necessary to alternate them in order to maintain this influence. In auy case, marked by an enfeebled capillary circulation, with tendency to congestion, especially of the nervous centers, Ergot may be prescribed with advantage. SCROPHULARIA MARILANDICA. 215 This stimulant influence upon the spinal-cord and sympathetic is manifested in contraction of non- striated muscular liber. Hence Ergot becomes an important remedy in hemorrhage when dependent upon atony. SCILLA MARITIME (Squill.) Preparation. — Prepare a tincture rroni the bulb gviij. to Alcohol 50° Oj. Dose from gtt. j. to gtts. x. In the larger dose, the Squill is a stimulant to mucous membranes, especially those of the air pas- sages, and may be employed to check profuse secre- tion. In minute doses it relieves irritation of mucous tissues and stimulates secretion. In dropsy, presenting a dry, harsh skin, parched tongue, fevered lips, and contraction of features, the Squill may be employed as a diuretic. In the majority of cases it has been used* with Digitalis, the dose being large, but it then proved beneficial in the opposite class of cases — where the circula- tion was feeble. Though it has been so extensively employed, it needs to be re-studied. SCROPHULARIA MARILANDICA. (FlGWORT.) Preparation. — Prepare a tincture from the leaves and root, gviij. to Alcohol 76° Oj. Dose from gtts. v. to gtts. xx. 216 SPECIFIC MEDICATION. The Scrophularia stimulates waste and excretion, and is probably as certain in its action as any of our vegetable alteratives. Beyond this it seems to exert a marked influence in promoting the removal of cacoplastic deposits. We employ it in scrofula, in secondary syphilis, in chronic inflammation with exudation of material of low vitality, and in chronic skin diseases. In the latter case it is frequently used as a local application, as well as an internal remedy. It exerts an influence upon the urinary and re- productive organs, and has been employed in some obscure affections of these with advantage. Still it is feeble and slow, and too much must not be ex- pected from it. SENECIO AUREUS. (Life Root.) Preparation. — Prepare a tincture from the fresh herb and root, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. x. (Much disappointment has been experienced from the purchase of the crude article when old, and from worthless preparations. I would advise the practitioner, when it can be ob- tained, to prepare his own tincture from the fresh plant.) The Senecio exerts a specific influence upon the reproductive organs of the female, and to a less extent upon the male. It relieves irritation and strengthens functional activity. Hence it has ac- SILPHIUM PERFOLIATUM. 217 quired the reputation of a " uterine tonic." It may be prescribed in all cases in which there is an atonic condition of ovaries or uterus, with derangement of function. It makes little difference whether it is anienorrhcea, dysmenorrhea or monorrhagia, or whether it-takes the form of increased mucous or purulent secretion, or displacement. The remedy acts slowly, and sufficient time must be given. In the male we prescribe it in cases of fullness and weight in the perineum, dragging sensations in the testicle, and difficult or tardy urination. In both male and female we sometimes use it with ad- vantage in painful micturition with tenesmus. SILPHIUM PERFOLIATUM. (Indian Cup-Plant) Pivparation. — Prepare a tincture from the fresh root, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. x. in water. The action of this variety of Silphium, if we are to believe the reports of the few who use it, is very direct and certain upon the chylopoietic vis- cera. It is claimed that it is one of the best reme- dies in the treatment of ague-cake, and congestion of liver and spleen, so frequently associated with chronic intermittents. It is but little employed, but deserves thorough investigation. 19 218 SPECIFIC MEDICATION. SILPHIUM GUMMNIFERUM. (Rosin Weed.) Preparation. — Prepare a tincture from the fresh plant, Sviij. to Alcohol 76° Oj. Dose, from gtt. j. to gtts. x. The tincture of the root may be em- ployed in some cases of cough, but is not so good as from the plant. The Rosin Weed exerts a direct influence upon the respiratory tract, especially upon the nerve cen- ters controlling the function. Its principal use thus far has been in the treatment of asthma, in some cases of which its action has been very decided. I think the cases in which it has proven most bene- ficial, are those in which there is a spasmodic dry cough, with sensations of dryness and constriction in the throat. I have not found it beneficial in lymphatic persons, or where there was congestion of mucous membranes, or profuse secretion. I have employed it in the treatment -of cough, with some advantage, but can not specify the cases in which it was useful or those in which it failed. It deserves thorough investigation, and will proba- bly prove a valuable remedy. The tincture of the root has been furnished the profession by druggists, and tlfe want of success with it is no evidence that the preparation from the plant is not anti-asth- matic. SODiE HYPOSULPHIS. 219 SODM HYPOSULPHIS. (Hyposulphite of Soda.) SOD^ SULPHIS. (Sulphite of Soda.) It is well to procure these salts of reliable manu- facturers (say Powers & Weightman), as there are many imperfect specimens in the market. The first is in the form of large colorless transparent crystals, freely soluble in water, the second in white pris- matic crystals soluble in four parts of cold water : a want of solubility should cause the preparation to be rejected. It should be kept tightly corked, for it changes by exposure to the air. Dose, grs. x. to grs. xxx. every two or three hours. In the first part of this work (Alkalies), will be found the general indication for the use of alkaline salts. They are very distinct, and can not be mis- taken— pallid mucous membranes, and white coat- ing on the tongue. We employ the Sulphite and Hyposulphite of Soda as antizymotics, where there are the indica- tions for the use of an alkaline salt as above. As a general rule, the indications for these salts will be — pallidity of mucous membranes, with 41* thick, pasty, white or dirty-white fur upon the tongue. The influence of zymotic causes of disease on the fluids and solids is not well understood, but we know that it impairs their life, even if it does not cause more rapid sepsis. In some cases this im- 220 SPECIFIC MEDICATION. pairnient of vital power is all the change that can be noted, retrograde metamorphosis progressing more slowly than in health or ordinary disease. But the remedies we are studying are more than antiseptics — they antagonize the zymotic cause whether it produces sepsis or not. In local diseases from a zymotic cause, as diph- theria, cynanche maligna, some forms of catarrh and influenza, erysipelas, surgical fever, etc., these remedies exert their specific action when locally employed, as well as in their internal administra- tion. The indications, however, must be as named above — pallidity, with pasty exudates upon tongue. Their action in arresting the growth of micro- scopic fungi, and during diseases arising from this cause, is specific. In yeasty vomiting, presenting sarcina ventriculi, the disease is speedily checked by the Sulphites. In some forms of apthous sore mouth and throat, speedy relief is given by their local application. Some chronic skin diseases are rendered very stubborn by these minute growths, and here also the Sulphites will prove valuable. SULPHUROUS ACID. We consider the Sulphurous Acid here, rather than under the head of Acids, from its relations to the Sulphites just noticed. We employ it as an anti- zymotic, and a parasiticide, and not for the common purposes of an acid, though here, as in the cases of the Alkaline Sulphites, there must be the SULPHUROUS ACID. 221 general indications for an acid, as there was with them for an alkali. The Sulphurous Acid, like the Alkaline Sul- phites, specifically antagonizes zymotic causes of disease. It is well to keep in mind the fact that this is something more than simply arresting or modifying the septic process, for we have al- ready seen that the zymotic influence frequently destroys the life of the* fluids and solids without producing putrescency. We prescribe Sulphurous Acid as an anti-zymotic in those cases which present reddened mucous membranes, with brownish coatings of tongue and sordes. Given, the indications for the use of an anti-zymotic, with the indications for the use of an acid, we select the Sulphurous Acid. Sulphurous Acid may be employed in yeasty vom- iting, in apthous mouth and throat, or wherever the presence of microscopic fungi is suspected, with the same certainty as the Sulphite of Soda. "We also use it in porrigo, trichosis of scalp, ptyriasis versi- color, with excellent results. As a local application it should be diluted with from two to six parts of water. I wish to call especial attention to its use in some diseases of the throat, by the spray or atomizing apparatus. In diphtheria, with dark-redness of mucous membranes, and fullness with relaxation, there is no local remedy equal to Sulphurous Acid spray. It is equally beneficial in those cases of cynanche maligna, with dark-redness of mucous 222 SPECIFIC MEDICATION. membranes. Whilst in ordinary sore throat from cold, with dusky discoloration, it offers one of the best local applications in the Materia Medica. SOLAN UM DULCAMARA. (Bittersweet). Preparation. — Prepare a tincture from the fresh twigs gathered in the fall, when the leaves have fallen, gviij. to Alcohol 70° Oj. Dose, from gtt. j. to gtts. X. The Bittersweet has the reputation of being a good alterative, in cutaneous diseases, syphilis, scrofula and inflammatory deposits, and we con- clude that it increases waste and excretion. It ex- erts a marked influence upon the cerebro-spinal centers, when used in large doses, but this has not been studied. I would advise the employment of the remedy in small doses in those cases of chronic disease in which the circulation is feeble, the hands and feet cold and purplish, with fullness of tissues and ten- dency to oedema. I do not know that it will prove better than other remedies, but it deserves investi- gation. SPONGIA USTA. (Burnt Sponge). Take of ordinary sponge a sufficient quantity, cut it in pieces, and burn it in a close iron vessel until it is brown and can be pulverized without much SPONGIA URTA. 223 trouble. Now, take of this powder four ounces, pack in a percolator, and gradually add Alcohol 76° Oj Dose of the tincture from the fraction of a drop to 5ss. I give the formula for the preparation of a tinc- ture of burnt sponge, not because I think it pos- sesses all the properties attributed to it by Homoeo- paths, but that it may be tested. I have used it in some cases with seeming advantage, and have seen results following its prescription by others, that in the ordinary use of medicine we would call remark- able cures. A quotation from Jahr's Repertory will show the Homoeopathic uses : " Diseases of the lymphatic vessels and glands ; heat, with dry, hot skiu, thirst, headache and de- lirium ; redness of the eyes, with burning and lachrymation ; frequent eructations, with cutting and tearing in the stomach ; relaxed feeling in the stomach, as if the stomach were open ; orchitis ; in- duration of the testes; pain in the larynx on touch- ing it and turning the head ; burning in the larynx and trachea ; dryness, husky and hoarse voice ; inflam- mation of the larynx, trachea and bronchi ; croup ; laryn- geal and, tracheal phthisis ; cough, deep from the chest, with soreness and burning, or chronic cough with yellowish expectoration and hoarseness ; wheezing inspirations ; asthma with amenorrhoea ; goitre ; hard goitre.' 224 SPECIFIC MEDICATION. STAPHYLEA TRIFOLIA. (Bladder Nut.) Preparation. — Prepare a tincture from the bark of the root, Sviij. to Alcohol 76° Oj. Dose from gtts. v. to 5j. The Staphylea has been confounded with the Ptelea, until we hardly know whether a writer in the olden times was describing one or the other. The probabilities are, however, that the articles de- scribed by Prof. I. G. Jones, and valued so highly by him as a tonic, was the article under considera- tion. At least it would be well for some of our friends who know the article, to procure specimens and thoroughly test it. Dr. Jones claimed that it was a pure unirritating tonic, having a soothing influence upon mucous membranes. He employed it in the convalescence after fevers and inflammations, and whenever the stomach was feeble and irritable. STILLINGIA SYLVATIOA. (Stillingia.) Preparation. — Prepare a tincture from the recent dried root, Sviij; to Alcohol 98° Oj. Dose from gtt. j. to gtts x. Stillingia increases waste and excretion, but its principal action probably is upon the lymphatic sys- tem, favoring the formation of good lymph, hence good blood and nutrition. Experience shows that it favorably influences the system in secondary STILLINGIA SYLVATICA. 225 syphilis, in some forms of scrofula, and in cases of chronic disease where the tissues are feeble and not readily removed and renewed. I believe it to be more especially useful in those cases where there is predominant affection of mucous membranes, and secondly, where the skin is involved. In these cases I have used the simple tincture as above, largely diluted with water, with much better results than I have obtained from any of the compounds of Stillingia or alterative syrups. Evidently in the ordinary manufacture of " Com- pound Syrup of Stillingia," the virtues of Stillingia, if it has any, are wholly lost, simply because water or dilute alcohol is not a proper menstruum. Stillingia exerts a specific influence upon the mucous membranes of the throat, larynx, and bron- chii, relieving irritation and favoring^iormal nutri- tion and functional activity. Some cases of chronic pharyngitis of years' standing, have been relieved by this remedy, after other treatment had failed. It is an excellent remedy in the treatment of some cases of chronic laryngitis, speedily relieving the irritation and cough, and we also employ it in chronic bronchitis with like good results. Now if it is possible to determine the class of cases in which it is thus beneficial, the reader may use it with advantage. So far as my experience extends, they are those with tumid, red, glistening mucous membranes, with scanty secretion. This condition indeed seems to be the index for the use of the remedy for every 226 SPECIFIC MEDICATION. purpose. In syphilis, in scrofula, in chronic inflam- mation with deposits, the same red glistening color, with scanty secretion, is my guide to the use of Stillingia. STRYOHNOS NUX VOMICA. (Nux Vomica.) Preparation. — Prepare a tincture from freshly powdered seeds, Sviij. to Alcohol 76° Oj. Dose, from the fraction of a drop to five drops. A solu- tion of Strychnia may be prepared after the follow- ing formula : Jfy Sulphate of Strychnia, grs. iv. ; Water, §iy, ; dose, gtts. v. -^ gr. to gtts. xx. ^ gr. Nux Vomica exerts a specific influence upon the intestinal canal and associate viscera that renders it a most valuable remedy. In minute doses we employ it to arrest nausea and vomiting, when this arises from gastric irritabil- ity and not from irritant material in the stomach. The cases are those in which there is feebleness of the organs, and not where there is irritation and in- flammation. For this purpose we employ it in cholera infantum with marked benefit, and in cholera morbus and Asiatic cholera to relieve this symptom. It is the remedy in all cases of congestion of liver, spleen, or portal circle. Given, a feeling of fullness in right hypochondrium, pain in side or shoulder, sallowness of face, yellowness of eyes, yellow coat on tongue, I prescribe JStix Vomica with a certainty that I never felt in the olden time. STRYCHNOS NUX VOMICA. 227 If an intermittent fever presents these evidences of visceral derangement, £Tux Vomica is the antipe- riodic, or at least it prepares the way for the kindly and curative action of Quinine. In bilious remittent fevers with these symptoms, J^ux Vomica is the first remedy indicated. In diarrhoea with these symp- toms we prescribe it with the certainty that the dis- charges will be speedily arrested, and the stomach and intestinal canal left in good condition. In dys- pepsia with these symptoms, we obtain speedy and permanent relief from the use of the remedy. It is here, as we have found it in the considera- tion of other remedies, if you can once determine the exact indication for its use, you may employ it whenever you find these indications, no matter what may be the name of the disease, or the condition of the patient otherwise. The influence of Kux Vomica and Strychnia upon the spinal cord is well known, and this seems to be its principal use in medicine. "Whilst I think it better, in the majority of cases, to restrict its use as above, there are some in which we employ it for its influence upon the nervous system alone. These are : — In typhoid and asthenic disease, where there is impairment of spinal innervation, and in conse- quence imperfect or enfeebled respiration, we give Strychnia or Nux Vomica with advantage. Indeed, in those cases in which the respiratory function can only be carried on under the influence of the will, it is the only remedy we can rely on. 228 SPECIFIC MEDICATION. In the same classes of disease, the tendency to retention of urine is met by the use of the same remedy. In some cases of the same diseases, where a feeble circulation is associated with general impairment of muscular power, and inability to co-ordinate muscular movement, we use Eux Vomica with ad- vantage. Nux Vomica or Strychnia should never be em- ployed in the treatment of paralysis so long as any evidence of inflammatory action exists ; neither should it be used, if there are marked evidences of cerebro-spinal congestion, until this is removed. It is the first remedy employed in cases of paralysis presenting the symptoms of visceral derangement we have already named. In other cases it is only em- ployed as a nerve stimulant, when the nerve centers are free from disease. SULPHUR. Preparation. — Prepare Sulphur for dispensing, by thorough trituration with two parts of Sugar of Milk. Dose from gr. j. to 5ss. We employ Sulphur as a restorative in those cases in which there is a deficiency of this element in the blood. "All the protein-compounds contain Sul- phur, which seems to be one of their essential con- stituents, not capable of entire separation without the complete destruction of the organic substance," (Carpenter). There are few, probably, who have SULPHUR. 229 thought of Sulphur in this relation ; they supply Iron as the "basis of red corpuscles, Phosphorus for the nutrition of the nervous system, but the protein tissues must get their supply of Sulphur from the food, or do without. The indication for the use of Sulphur as a resto- rative is, enfeebled nutrition associated with de- coloration of tissues, aud secretions. The skin is blanched, the iris loses color, the hair is lighter in color in the young, changes rapidly to gray in the middle aged, and the urine is light colored as is the feces. The presence of cystine in the urine is an indication for the administration of Sulphur. We also employ Sulphur in those cases in which there is excessive fetor of the excretions. We will occasionally find a case of chronic disease, in which the breath, the secretion from the skin, the urine, and the feces have a peculiar cadaverous odor, and we notice that with this there is a remarkable ten- dency to decomposition, and to breaking down of tissue. It is possible that this may be explained, by the necessity of Sulphur in the formation of the tau- rine of the bile. If this secretion of the liver is the normal antiseptic, and controls putrescency in the body, we can see why a deficiency of Sulphur may lead to the condition above named, and its ad- ministration be directly curative. 230 SPECIFIC MEDICATION. SYMPLOCARPUS FCETIDUS. (Skunk Cabbage.) Preparation. — Prepare a tincture from the fresh root, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. v. Though the Skunk Cabbage has been extensively used, it has been in combination with other reme- dies, and the reports are so vague that we can not estimate its remedial action. It exerts a very de- cided influence upon the nervous system, relieving irritation and preventing normal functional activity. This, probably, will be its principal use. The remedy deserves to be thoroughly studied. TANACETUM VULGARE. (Tansy.) Preparation. — Prepare a tincture from the fresh herb gathered in August, using oviij. to Alcohol 76° Oj. Dose gtts. j. to gtt. xx. As a local ap- plication to the throat use one part of the tincture to four to ten parts of hot water, with, a spray appa- ratus ; or not having this, vaporize the fluid and let the patient inhale the steam. In small doses the tincture as above prepared will furnish a cheap and agreeable stomachic, reliev- ing irritation and improving functional activity. It exerts a decided stimulant influence upon the female reproductive organs, and may be employed in functional diseases when such influence is desir- able. TELA ARANE^:. 231 As a local application by spray or inhalation, it is a very valuable remedy in the treatment of diph- theria, and some forms of acute inflammation of the throat, and in epidemic catarrh. I have em- ployed it in these cases with most marked advan- tage, and value it very highly. TARAXACUM DENS LEONIS. (Dandelion.) Preparation. — Prepare a tincture from the fresh root gathered in July or August, sviij. to Alcohol 76° Oj. Dose from gtts. v. to oss. The Taraxacum loses its medical properties by drying, hence that usually supplied by the drug- trade is wholly inert. Prepared as above, it will prove a valuable remedy. It exerts a stimulant influence upon the entire gastro-intestinal tract, promoting functional activity. Whilst its action is feeble, it is very certain, and will frequently prove more desirable than the more active remedies. TELA ARANE^]. (Spider's Web.) From the web of the common house spider, pre- pare a tincture by macerating §ij. in Alcohol 98° Oj. for ten days. Dose, gtt. j. to gtts. x. It is claimed to be a very certain remedy in the cure of intermittents. I give a formula for its preparation, that it may be tested. The tincture of 232 SPECIFIC MEDICATION. the Aranea Diadema is employed in Germany by some Homoeopaths, and cases reported in which the cure was speedy and permanent. THUJA OCCIDENTALIS. (Arbor Vit^e.) Preparation. — Prepare a tincture from the fresh leaves, oviij. to Alcohol 76° Oj Dose from gtt. j. to gtts. XX. The leaves of the Arbor Vitse has been a popular remedy in the treatment of intermittent and re- mittent fever, rheumatism, scurvy, etc. It would be well for some of our practitioners to prepare a tincture and test it. TRIFOLIUM PRATENSE. (Red Clover.) Preparation. — Prepare a tincture from the recently dried blossoms of Ked Clover, Sviij. to Alcohol 50° Oj. Dose from gtt. j. to gtts. x. The Red Clover exerts a specific influence in some cases of whooping cough, and in the cough of measles. It is not curative in all, but when it does good, the benefit is speedy and permanent. It may also be prescribed in other cases of spasmodic cough, in laryngitis, bronchitis and phthisis. We should be able to tell the exact condition where it proves beneficial, and where it fails, but thus far the use has been wholly empirical. In the farther use of the remedy all the symptoms should be noted. URTICA DIOICA. 233 It has given much satisfaction thus far, and is likely to prove a very valuable remedy. TRILLIUM PENDULUM. (Bethroot.) Preparation. — Prepare a tincture from the fresh root, Sviij. to Alcohol 76° Oj. Dose from gtt. j. to gtts. x. The common use of Trillium in large doses ob- tained its astringent influence, possibly from the tannin it eontaius. The preparation from the fresh root named above, is but slightly astringent. We would employ it in disease of mucous mem- branes with increased secretion, and expect decided benefit. In the earlier part of my practice I used Trillium in chronic bronchitis, in chronic catarrh, in cough with free expectoration, with excellent re- sults. It needs to be thoroughly studied, and it will probably supply a want in our Materia Medica. URTICA DIOICA. (Common Nettle.) Preparation. — Prepare a tincture from the fresh plant, Sviij. to Alcohol 76° Oj. Dose from gtts. j. to gtts. x. The Urtica has been employed in some diseases of the bowels, with reported good results. An old practitioner informs me, that in chronic disease of the large intestine with increased mucous secretion, 20 234 SPECIFIC MEDICATION. he has never found anything so beneficial as this remedy. It has also been used in diseases of the urinary organs. \ It is now but little used, but deserves investiga- tion. VALERIANA OFFICINALIS. (Valerian.) Preparation, — Prepare a tincture from the root (as recent as can be obtained), gviij. to Alcohol 50° Oj. JDose from gtts. ij. to gtts. xx. Valerian is a cerebral stimulant, and may be em- ployed wherever a remedy of this character is indi- cated. It allays nervous irritability, modifies or arrests pain, promotes rest, and favors sleep, where these conditions result from an enfeebled cerebral circulation. It is very extensively used, and many times without benefit, as the condition of the ner- vous centers is very rarely taken into consideration. VERATRUM VIRIDE. (Veratrum.) Preparation. — Prepare a tincture from the recent root, not fully dried, oviij. to Alcohol 76° Oj. Dose from the fraction of a drop to three drops. Vera- trum from Western New York furnishes an excel- lent remedy, as is that from North Carolina aud Northern Georgia. Specimens I have seen from the Western States were worthless. The root should be dug in August or September, freed from VERATRUM. 235 dirt, and dried sufficiently to permit of shipment to the place of manufacture. Now, it should be immediately crushed, and the year's supply of tinc- ture prepared. As commonly prepared for the drug trade, (Nor- wood's excepted), it is made of the dried root kept in stock from year to year, and possesses very feeble, if any medical properties. In this case, as with some other remedies, the process of drying destroys that finer medical action upon which we depend to influence the sympathetic nervous system. We employ the Veratrum to lessen the frequency of the heart's action. When properly used it not only lessens the frequency of the pulse, but it re- moves obstruction to the free circulation of the blood, and thus gives slowness, regularity, freedom, and an equal circulation in all parts of the body. This action we call arterial sedation, though the name is not a good one. To obtain this action it is necessary that the remedy be used in small doses, frequently repeated, and that sufficient time be given to accomplish the object without disturbing function or producing depression. Veratrum is sedative in large doses, and its influ- ence upon the heart may be speedily obtained in this way. But in this case its influence is depress- ing. It evidently causes slowness of the pulse by paralyzing the cardiac nerves. If the influence is continued there is impairment of the circulation, with tendency to congestion. As a general rule, 236 SPECIFIC MEDICATION. the influence of large doses can not be maintained ; either the remedy produces irritation of the stomach, so that it will no longer be tolerated, or its depressing influence upon the circulation becomes so great that it must be suspended. . In small doses the Veratrum is a stimulant to all the vegetative processes. Acting through the sym- pathetic or ganglionic system of nerves, it removes obstruction to the capillary circulation, gives tone to the vascular system, and strength to the heart. As the obstacles to a free circulation are removed, and the vessels through which the blood is distrib- uted and returned, regain their normal, condition, there is less necessity for increased action upon the part of the heart ; and as the power of the heart is increased, there is less necessity for frequent con- traction. I give this as a theory of the action of Veratrum, but whether true or not, there is no question with regard to the facts as abgve stated. Veratrum is the remedy for sthenia, where there is a frequent but free circulation. It is also the remedy where there is an active capillary circula- tion, both in fever and inflammation. A full and bounding pulse, a full and hard pulse, and a corded or wiry pulse, if associated with inflammation of serous tissues, call for this remedy. As was remarked when describing Aconite, the Veratrum exerts a similar influence in acute inflam- mation, and directly controls the inflammatory pro- cess in its first stages. As a rule, the remedies VERATRUM. 237 that will cure fever will cure inflammation. To this I believe there are no exceptions, if a proper diagnosis is made, and we are governed by the same indications for prescribing. Aconite, Yeratrum, Gelseminum, Belladonna, E"ux Vomica, Quinia, and other direct remedies, may be prescribed with the same certainty in inflammation as in fever. There is the same necessity for securing a good condition of stomach and upper intestine for digestion, and giving proper food. The same necessity for secur- ing normal waste and excretion, and having the tis- sues renewed from good blood. The pallid tongue calls for alkalies, the dark redness of mucous mem- branes for acids, the pasty white coat for the sul- phites, etc. My experience teaches me that local inflamma- tions are reached directly by this direct medication, and with a certainty a hundred times greater than by the old routine of internal and external counter- irritation. It makes no difference where its loca- tion, how great or how little, the treatment is ex- actly the same as for a fever presenting the same symptoms or indications for remedies. It must not be expected that the indications for remedies will be as pronounced in the case of in- flammation as in fever, but they are always suffi- cient. I have treated inflammation of the lungs with Veratrum alone, Yeratrum with Gelseminum, Yera- trum with Ipecac, Ipecac alone, Aconite alone, with a success I nevpr saw obtained from the use of nau- 238 SPECIFIC MEDICATION. seants and counter-irritation. Other cases required the use of the Sulphites, of Quinia, or the mineral acids. I am not alone in this experience, for scores of our more recent students, who have learned this practice in lectures, give testimony to its success. The local application of Veratrum, in the early stages of a superficial inflammation, will not {infre- quently arrest its progress. In this way we use it in erysipelas, in phlegmous inflammation of cellular tissue, in felons, diseases of the bones, tonsilitis, etc. "We employ Veratrum in the treatment of chronic disease for its stimulant influence upon the vegeta- tive processes. Properly used, we find that it lessens the frequency of the pulse, giving a free and uni- form circulation ; it lessens the temperature ; it in- creases waste and excretion ; and finally it stimu- lates digestion and nutrition. My friend, Prof. Howe, regards it as one of the most direct and certain " Alteratives " in the Mate- ria Medica, and in this opinion he is supported by a large number of practitioners. If the remedy has the action above named, we can readily see how it favorably influences chronic disease, and how fre- quently it may be employed with advantage. VEKBASCUM THAPSUS. (Mullein.) Preparation. — Prepare a tincture from the fresh tops and smaller leaves when the plant is in flower, Sviij. to Alcohol 50° Oj. Dose from gtts. v. to 5j- VIBURNUM PRUNIFOLIUM. 239 The Verbascurn exerts a mild influence upon the nervous system, quieting irritation and promoting sleep. It also allays bronchial irritation, and checks cough. It is very feeble, and has but a limited use. VIBURNUM OPULUS. (High Cranberry.) Preparation. — Prepare a tincture from the recent bark, gviij. to Alcohol 50° Oj. Dose, from gtts. v. to gtts. xx. The Viburnum has been employed as an anti- spasmodic with reported success, hence its name, cramp bark. If we are to be guided by the descrip- tions of our earlier practitioners, we would conclude that it exerted a direct influence in controlling spinal irritation, and spasmodic action arising from this. I have never used it, though I think it worthy a trial. VIBURNUM PRUNIFOLIUM. (Black Haw.) Preparation. — Prepare a tincture from the recent bark of the root, gviij. to Alcohol 50° Oj. Dose from gtts. v. to gtts. xx. It is claimed in the Southern States that the Viburnum is a specific against abortion. I have been told by several parties, that it was a common practice among planters to make their slaves drink an infusion of the Viburnum daily whilst preg- nant, to prevent abortion from taking the Cotton- 240 SPECIFIC MEDICATION. root. A physician from Texas assured me, that from an observation of fifteen years, he was confi- dent that it exerted this influence, and that he had prescribed it in many cases without a failure. If it exerts this influence upon the uterus, it will prove a valuable remedy, not only as anti-abortive, but in diseases of the reproductive organs. XANTHOXYLUM FRAXINEUM. (Prickly Ash.) Preparation. — Prepare a tincture from the berries, Sviij. to Alcohol 98° Oj. Dose from the fraction of a drop to five drops. The Xanthoxylum has been employed as a diffu- sible and topical stimulant. Its general stimulant action is not very marked, and there are many other remedies preferable. But as a stimulant to mucous tissues it has no equal in the Materia Medica. Whenever it is desirable to obtain such influence, whether of the throat, the gastrointesti- nal tract, the mucous membranes of the air-passages, or of the urinary organs, we are rarely disappointed in its action. Upon the throat, the stomach, and upon the intestines, it exerts a topical influence be- fore absorption. In small doses we occasionally employ it in chronic diseases of mucous surfaces, with good re- sults. The cases are as above, when the mucous membranes are enfeebled and relaxed, with hyper- secretion. INDEX. Analysis of Disease , 11 Administration of Medicines 24 Atony of Stomach.. 40 Alkaline Sulphites 47 Abies Canadensis 54 JEsculus Glabra... 54 iEsculus Hippocastanum 56 Acids 57 Alkalies 58 Achillea Millefolium.. 60 Aconitum Napellus 61 Actsea Alba 64 Agave Americana 65 Agrimonia Eupatoria. 66 Agrimony , 66 Aletris Farinosa , , 6 7 Alnus Kubra 67 Aloes 68 Ammonium, Bromide of 69 " • Iodide of. 70 Ampelopsis Quinquefolia 70 Amygdalus Persica 71 Anagallis Arvensis 71 Anemone Nemorosa 72 Apocynum Cannabinum 72 Aralia Hispida 74 Arnica Montana 74 Artemesia Absinthium 76 Artemesia Santonica , 76 Asclepias 77 21 242 INDEX. Asclepias Tuberosa 77 Aspidium Filix Mas 78 Asafsetida 79 Atropa Belladonna 79 Atropia 79 Apis Mellifica 82 Agaric r 83 Ash 126 American Coffee Tree 133 Apple Tree 190 American Centaury 205 Arbor Vitse 232 Best Menstruum for Medicines 28 Blood Poisons 47 Buckeye 54 Bromide of Ammonium 69 Belladonna 79 Boletus Laricis 83 Baptisia Tinctoria 86 Benzoic Acid 88 Berberis Vulgaris 89 Barberry 89 Bebeerina Sulphas 89 Bismuth 90 Bromide of Potassium 91 Bromine 91 Bidens Bipinnata 92 Bryonia 92 Brayera Anthelmintica 92 Blue Cohosh 99 Balmony 101 Bush Honeysuckle 115 Boneset , 122 Bowman's Boot 123 Balsam Apple 164 Black Hellebore 137 Blue Flag 146 Butternut 147 INDEX. 243 Blackroot . 151 Button Snakeroot. 153 Bugle Weed 156 Bayberry 163 Beech Drops 168 Black Pepper 1*75 Black Alder 182 Buckthorn * 196 Black Locust 202 Black Willow 205 Blood Boot 208 Bittersweet 222 Burnt Sponge 222 Bladder Nut 224 Beth Boot, 233 Condition of Digestive Organs 17 Classification of Medicines 37 Condition of the Stomach 39 Circulation 41 Chloral Hydrate 104 Cardiac Stimulants 45 Cohosh "White , 64 " Black 64 " Blue 99 Century Plant 65 Calendula Officinalis 92 Calx 93 Camphor 93 Cannabis Sativa 94 Cantharis Vesicatoria 95 Cactus Grandiflorus 95 Capsicum 97 Cayenne Peppei 97 Carbo Ligni 98 Charcoal 98 Cassia Acutifolia 99 Caulophyllum 99 Ceanothus Americanus 101 244 INDEX. Celastrus Scandens 101 Chelone Glabra 101 Chimaphilla Umbellata 101 Cb-ionantlius Yirginica 102 Chloroform 103 Chloral Hydrate 104 Cistus Canadensis 108 Cinnamon 109 Clematis Yirginiana 110 Coffee 110 Collinsonia Canadensis 110 Colchicum Ill Colocynth 112 Cypripedium Pubescens 113 Canada Fleabane 119 Columbo 125 Cleavers 127 Cranesbill 130 Cotton 132 Catnip 165 Cod Liver Oil 167 Crawley 187 Crowfoot 196 Disease, Analysis of 11 Diagnosis Specific 14 Disease, Rule for Measuring 15 Digestive Apparatus, Condition of 17 Difference from Homoeopathy 21 Dose of Medicine 30 Differential Therapeutics of Acconite and Yeratrum 62 Dwarf Elder 74 Datura Stramonium 114 Delphinum Staphisagria 114 Delphinum Consolida 115 Diervilla Canadensis 115 Digitalis Purpurea 115 Dioscorea Yillosa 116 Drosera Eotundifolia 117 INDEX. 245 Excretion 20 Epigea Kepens lis Epilobium Palustre 118 Erechthites Hieracifolius 119 Erigeron Canadense 119 Eryngium Aquaticum 120 Euonymus Atropurpureus, 120 Eupatorium Aromaticum 121 Eupatorium Teucrifolium 121 Eupatorium Purpureum 122 Eupatorium Perfoliatum 122 Euphorbia Corollata 123 Elecampane 142 Elaterium 162 Elder 207 Ergot 213 Ferrum 123 Frasera Carolinensis 125 Fraxinus Sanibucifolia. 126 False Bittersweet 101 Fringe Tree 102 Foxglove 115 Fireweed 119 Fleabane 119 Five Fingers 70 Fresh Medicines , 32 Form of Medicine 27 Feverfew '.. 186 False Wintergreen 190 Figwort , 215 Good Nursing * 24 Galium Aparine 126 Gaultheria Procuinbene 127 Gelseminum Sempervirens 127 Gentiana Lutea 129 Gentian , 129 Geranium Maculatum ..130 Gerardia Pedicularia 130 Gillenia Trifoliata 130 246 index. Gillenia Stipulacea 130 Glycerine 131 Gnaphalium Polycephaluni 132 Gossypium Herbaceum 132 Guaiacum Officinale 133 Gymnocladus Canadensis 133 Golden Seal 139 Ginseng 168 Glycerole of Tar 176 Hemlock 54 Horse Chestnut 56 Hemp, Indian 72 Honey Bee 82 Hemp 94 Hamamelis Yirginica , 134 Hedeoma Pulegioides ' 136 Helianthemum Canadense 136 Helleborus Niger 137 Helonias Dioica 137 Hepatica Americana 138 Heracleum Lanatum 138 Hydrangea Aborescens 139 Hydrastis Canadensis 139 Hyoscyamus Niger 140 Henbane -140 Hoarbound 159 Hypodermic Use of Morphia 170 Hypophosphites 173 Hair-Cap Moss 181 High Cranberry 239 Haw, Black 239 Irritation of Stomach 39 Innervation 50 Inula Helenium 142 Iodine 142 Iodide of Potassium 142 " " Sodium 143 " " Ammonium 70,143 « " Starch 144 INDEX. 247 Ipecacuanha 144 Ipomcea Jalapa 145 Iris Versicolor 146 Iron 123 Iron by Hydrogen 123 Iron, Tincture of Chloride of 123 Indian Physic 130 Ice Plant 162 Indian Cup-Plant 217 Jamestown Weed 114 Jalap 145 Jeffersonia Diphylla 147 Juglans Cinerea ...f 147 Juniperus Sabina 148 Jacob's Ladder 188 Kalmia Latifolia ./. 148 Life, Kenewal of „ ' 18 Laws of Cure 21 Liquor Bismuth 90 Lime 93 Lady's Slipper. 113 Larkspur 115 Liverleaf 138 Laurus Sassafras 149 Larix Americana 150 Lavandula Vera 150 Lavender „ 150 Leonurus Cardiaca 151 Leptandra Virginica 151 Leptandrin 153 Liatris Spicata , 153 Liquidambar Styraciflua 153 Liriodendron Tulipifera .'..154 Lobelia Inflata 154 Lycopus Virginicus ....156 Lion's Foot 164 Lungwort 187 Life Root 216 248 INDEX. Measuring Disease 15 Medicines, Administraiion of 24 " Should act slowly 26 " Pleasant 29 " Dose of 30 " Proportion of 31 Malaria 49 Maguey 65 Milkweed 77 Marigold 92 Masterwort 138 Motherwort 151 Magnesia, Sulphite of 157 Magnolia 159 Marrubium Yulgare 159 Maruta Cotula 160 Mayweed 160 Menispernum Canadense 160 Mentha Viridis 160 Mitchella Eepens 161 Manatropa Uniflora 162 Myrica Cerifera 163 Momordica Balsarnina 164 Male Fern 78 Morphia 170 May Apple 177 Mullein 238 Nosology 11 Nutritive Processes 53 Night Blooming Cereus 95 Nabalus Albus « 164 Nepeta Cataria 165 Nicotiana Tabacum 165 Nympilsea Odorata 166 Nux Vomica ! 226 Nettle 233 Opposition to Disease 9 Opponens Opponenda 22 INDEX. 249 Onething at a time 25 Office Pharmacy 35 Objects of Treatment 38 Oleum Morrhuse 167 Origanum Yulgare 167 Orobanche Yirginiana 168 Opium, s 169 Proper Food 19 Percolation 36 Physical Properties of Kemedies 34 Pharmacy, Office .' 35 Peach Tree 71 Polyporus Officinalis 83 " Pinicola , 84 Pipsissewa 101 Pennyroyal 136 Partrigeherry 161 Pseonia Officinalis 168 Panax Quinquefolium 168 Papaver Somniferum 169 Peroxide of Hydrogen : — 172 Phosphorus 172 Phosphate of Soda 173 Phytolacca Decandra 174 Poke 174 Piper Nigrum 175 Pix Liquida 176 Plantago Cordata 177 Podophyllum 177 Podophyllum 177 Polemonium Beptans 180 Polygala Senega ; 180 Polygonum Pun ctatum 181 Polypodium Vulgare 181 Polytrichum Juniperum 181 Populus Tremuloides ■ 182 Poplar 182 Prinos Verticillatus 182 250 INDEX. Primus Virginiana 183 Ptelea Trifoliata 183 Pteris Atropurpurea .184 Petroleum 184 Propylamin 185 Pterospora Andromeda 187 Pulinonaria Officinalis 187 Pulsatilla Nigricans 188 Pulsatilla 188 Pyrethrum Parthenium 189 Pyrola Eotundifolia , 190 Pyrus Malus 190 Potassii Ferrocyanuretum 195 Prussiate of Potash 195 Poison Oak 200 Queen of the Meadow 122 Quercus Eubra 191 Quinia Sulphas 191 Eule for Measuring Disease 15 Bemoval of "Worn-out Tissue 17 Eetrograde Metamorphosis 52 Ked Chickweed 71 Eed Eoot 101 Eock Eose 136, 108 Rock Brake 184 Eed Oak 191 Ranunculus Bulbosus 196 Ehamnus Catharticus. 196 Eheum Palmatum 197 Ehubarb 197 Bhododendron Chrysanthum 199 Bhododendron 199 Ehus Glabrum 199 Ehus Toxicodendron 200 Eobinia Pseudo- Acacia 202 Eumex Acetosella 202 Eumex Crispus 203 Euta G-raveolens 204 INDEX. 251 Eue 204 Bosin-weed 218 Eed Clover 232 Specific Medication, Theory of 9 " Use of the Word 10 Selection of Eemedies 13 Specific Diagnosis 14 Single Eemedies 16 Similia Similibus 21 Strength of Fluid Eemedies 33 Sedation, Theory of 44 Santonine 76 Silkweed 77 Spanish Fly 95 Spanish Needles 92 Senna 99 Stone Eoot 110 Staphysagria 114 Sundew 177 Seven Barks 139 Savin -148 Sweet Gum 153 Spearmint 160 Senega 180 Sumach 199 Sheep Sorrel 202 Sabbatia Angularis 205 Salix Nigra ....205 Salvia Officinalis 206 Sage 206 Sambucus Canadensis 207 Sanguinaria Canadensis 208 Sanicula Marilandica 208 Sanicle 208 Sarracenia Purpurea 209 Scutellaria Lateriflora „ 212 Skull Cap 212 Secale Cornutum 213 252 INDEX. Scilla Maritima 215 Squill 215 Scrophularia Marilandica 215 Senecio Aureus 216 Silphium Perfoliatum 21? Silphium Gumniferum 218 Sodae Hyposulphis 219 Sodse Sulphis 219 Sulphurous Acid 220 Solarium Dulcamara 222 SpongiaUsta 222 Staphyllea Trifoliata , 224 Stillingia Sylvatica 224 Strychnos Nux Yomica 226 Strychnia 227 Sulphur * 228 Symplocarpus Foetidus 230 Skunk Cabbage 230 Theory of Specific Medication 9 " " Sedation 44 Temperature 46 Tag Alder 67 Trailing Arbutus 118 Twinleaf 147 Tobacco , 165 Tar 176 Thuja Occidentalis 232 Trifolium Pratense 232 Trillium Pendulum ." 233 Tanacetum Yulgare 233 Use of the Word Specific 10 Unicorn Poot 136 Urtica Dioica 233 Virgin's Bower 110 Vegetative Processes 50 Valeriana Officinalis 234 Valerian , 234 Veratum Viride 234 mDBX. 253 Verbascum Thapsis 238 Viburnum Opulus 289 Viburnum Prunifolium 239 Want of Vital Power 42 Waste and Excretion 48, 51 White Cohosh 64 Wind Flower 72 Wormseed 76 Wormwood 76 Wild Indigo 86 Wild Yam 116 Water Eryngo 120 Wahoo 120 White Snakeroot 121 Wild Hoarhound 121 Wild Ipecao •- 123 Wintergreen 127 White Balsam 132 Witch Hazel 134 White Pond Lilly 166 Water Pepper 181 Wild Cherry 183 Wafer Ash 183 Xanthoxylum Fraxineum 240 Yellow Jessamine 127 Yellow Poplar 154 Yellow Parilla 160 Yellow Dock 203 Zymotic Causes of Disease 47 Dr. Job T. Dickins, 8 Pleasant Street, Newburyport. -•'---■•■• |gUKj» MMfak