St. John's Wort
Scientific Name: Hypericum perforatum
Botanical and Historical Origin
Europe and North Africa.
Evolution of Historical Use
Used in the Middle Ages to drive away evil spirits ('Fuga Daemonum').
Traditional Cultivation and Harvesting
Hardy perennial. Small perforated glands in the leaves contain the active hypericin.
Historical Medicinal Profile
Historical Internal Use
nerve pain, melancholy
Historical External Use
nerve damage, burns
Safety and Modern Toxicology
Induces the CYP3A4 enzyme in the liver, drastically accelerating the metabolism of modern pharmaceuticals (birth control, heart meds, antidepressants), rendering them useless and causing systemic failure. Interacts dangerously with many pharmaceuticals. Causes photosensitivity.
Circular Codex References
This ingredient is also documented in our livestock-focused Plant Codex, where you can find detailed information on its identification, veterinary safety, and farmstead management.
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